Kolorektal premalign polipler ile mide premalign lezyonları arasındaki ilişki

Yıl 2020, Cilt: 28 Sayı: 2, 42 - 46, 30.08.2020

Harun Erdal Armağan Günal Bülent Çelik Yusuf Sakin Cemal Erçin Ahmet Uygun Mustafa Gülşen

https://doi.org/10.17940/endoskopi.795866

Öz

Giriş ve Amaç: Kolorektal premalign lezyonların en önemlisi poliplerdir. Poliplerin histopatolojisi ve boyutlarına göre malignite riski değişmektedir. Ayrıca mide mukozasında displazi, atrofi, intestinal metaplazi, polip ve Helicobacter pylori gibi faktörler de mide için prekanseröz durumlardır. Çalışmamızın amacı; kolorektal poliplerin yerleşimi, boyutu, sayısı ve patolojisi ile midenin premalign lezyonları arasındaki ilişkiyi ortaya koymaktır.
Gereç ve Yöntem: Çalışmamız Ekim 2016 ile Ekim 2019 tarihleri arasında 18 yaş ve üzeri hastalara aynı gün yapılan özofagogastroduodenoskopi ve kolonoskopi verilerinin değerlendirildiği retrospektif bir çalışmadır. İnflamatuvar barsak hastalığı olan, mide kanseri ve kolorektal kanser tanısı alan, mide biyopsisi alınmayan, barsak temizliği yetersiz olan ve işlemi tamamlayamayan hastalar çalışmaya dahil edilmemiştir.
Bulgular: İki yüz elli yedi hastanın %58.0’i erkek ve %80.9’u 50 yaşın üzerindeydi. Kolorektal poliplerin çoğunluğu distal yerleşimliydi (%59.1). İleri adenomatöz polip (İAP) sıklığı %24.9 olup ileri adenomatöz polip varlığı ile 50 yaş altı ve üzeri hastalar arasında ve cinsiyete göre istatistiksel fark yoktu (p: 0.659 ve p: 0.747). Helicobacter pylori, atrofi, intestinal metaplazi, displazi ve polip gibi midenin premalign lezyonları ile ileri adenomatöz polip arasında istatistiksel olarak anlamlı bir ilişki gözlenmedi (p: 0.301 ).
Sonuç: Kolorektal poliplerin yeri, sayısı ve ileri adenomatöz polip ile premalign mide lezyonları arasında ilişki saptanmamıştır.

Anahtar Kelimeler

Kolorektal polip, premalign, prekürsör, mide lezyonu

Relationship between premalignant colorectal polyps and premalignant gastric lesions

Öz

Background and Aims: Polyps are the most important premalignant colorectal lesions. The risk for malignancy with polyps differs with its histopathology and size. Moreover, factors in the gastric mucosa such as dysplasia, atrophy, intestinal metaplasia, polyp, and Helicobacter pylori are precancerous conditions for the stomach. In this study, we studied the relationship between the location, size, number, and pathology of colorectal polyps and premalignant gastric lesions. Material and Methods: This was a retrospective study that analyzed the data of patients of age ≥18 years who underwent esophagogastroduodenoscopy and colonoscopy on the same day between October 2016 and October 2019. Patients with a history of an inflammatory bowel disease, diagnosis of gastric cancer and colorectal cancer, those who did not undergo gastric biopsy, and those in whom sufficient colonic irrigation was not performed and who could not complete the procedure were excluded from the study. Results: Of the 257 patients, 58% were men and 80.9% were >50 years of age. The location of the majority of colorectal polyps was distal (59.1%). The incidence of Advanced Adenomatous Polyp was 24.9%, with no statistical difference in the presence of Advanced Adenomatous Polyp between the ages younger and older than 50 years according to their gender (p=0.659 and p=0.747). No statistically significant relationship was observed between Advanced Adenomatous Polyp and premalignant gastric lesions, such as Helicobacter pylori, atrophy, intestinal metaplasia, dysplasia, and polyp (p=0.301). Conclusions: No relationship was observed among the location, number, and Advanced Adenomatous Polyp rate of colorectal polyps and premalignant gastric lesions.
Keywords: , , ,

Anahtar Kelimeler

Colorectal polyp, premalignant, precursor, gastric lesion

Kaynakça

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