Üreterolitotripsi Sonrası Distal Üreter Taşlarında Taş Fragmanlarının Çıkarılması İçin Flush-out Tekniği ve Basketin Karşılaştırılması: Prospektif Randomize Çalışma
Yıl 2025,
Cilt: 17 Sayı: 3, 157 - 163, 30.09.2025
Metin Savun
,
Ertuğrul Arıkız
,
Harun Özdemir
,
Emin Taha Keskin
,
Murat Şahan
,
Halil Lütfi Canat
Öz
Amaç: Bu prospektif, randomize çalışmada, distal üreter taşı olan hastalarda semi-rigid üreteroskopi sırasında taş fragmanlarının çıkarılması için basket ve flush-out tekniği karşılaştırılmıştır.
Gereç ve Yöntemler: Distal üreter taşı olan 84 hasta eşit olarak iki gruba ayrıldı. Grup 1’e nitinol basket kullanılarak taş çıkarma işlemi uygulanırken, Grup 2’ye irrigasyon basıncıyla üreteroskopun geri çekilmesi yoluyla pasif olarak taş fragmanlarının çıkarılmasını içeren flush-out tekniği uygulandı. Demografik veriler, taş özellikleri, operasyon sonuçları ve komplikasyon oranları kaydedildi.
Bulgular: Demografik veriler ve taş özellikleri iki grup arasında benzerdi. Grup 2, Grup 1’e kıyasla anlamlı derecede daha kısa median operasyon süresi (30’a karşı 45 dakika, p=0,020) ve taş çıkarma süresi (1’e karşı 10 dakika, p=0,001) gösterdi. Ameliyat sonrası birinci gündeki taşsızlık oranları gruplar arasında benzerdi (%97,6’ya karşı %100, p=1,000). Ameliyat sırasında ve sonrasındaki komplikasyon oranları benzerdi ve Satava, Clavien-Dindo sınıflandırmalarının dağılımında anlamlı bir fark yoktu.
Sonuç: Flush-out tekniği, distal üreter taşları için basket yöntemine güvenli ve etkili bir alternatif olup, daha kısa ameliyat süresi ve taş çıkarma süreleri ile karşılaştırılabilir klinik sonuçlar sunmaktadır. Basitliği ve uygun maliyeti, özellikle yüksek hacimli ve sınırlı kaynaklara sahip kliniklerde günlük üroloji pratiğinde daha yaygın bir şekilde uygulanmasını destekleyebilir.
Etik Beyan
Başakşehir Çam ve Sakura Şehir Hastanesi Klinik Araştırma Etik Kurulu Tarih: 29 Aralık 2021 Karar No: 287.
Destekleyen Kurum
Yazarlar, sunulan çalışma için herhangi bir kuruluştan destek almamıştır.
Kaynakça
-
1. Skolarikos A, Jung H, Neisius A, Petrik A, Kamphuis GM, Davis NF, et al. European Association of Urology Guidelines on Urolithiasis. Arnhem, The Netherlands: EAU Guidelines Office; 2025. ISBN: 978-94-92671-29-5. Available from: https://uroweb.org/guidelines
-
2. Khoder WY, Bader M, Sroka R, Stief C, Waidelich R. Efficacy and safety of Ho:YAG laser lithotripsy for ureteroscopic removal of proximal and distal ureteral calculi. BMC Urol. 2014;14:62. https://doi.org/10.1186/1471-2490-14-62
-
3. Matlaga BR, Chew B, Eisner B, Humphreys M, Knudsen B, Krambeck A, et al. Ureteroscopic Laser Lithotripsy: A Review of Dusting vs Fragmentation with Extraction. J Endourol. 2018;32(1):1–6. https://doi.org/10.1089/end.2017.0641
-
4. Santiago JE, Hollander AB, Soni SD, Link RE, Mayer WA. To Dust or Not To Dust: a Systematic Review of Ureteroscopic Laser Lithotripsy Techniques. Curr Urol Rep. 2017;18(4):32. https://doi.org/10.1007/s11934-017-0677-8
-
5. Tapiero S, Ghamarian P, Clayman R. A Technique to Flush Out Stone Fragments Through a Ureteral Access Sheath During Retrograde Intrarenal Surgery. J Endourol Case Rep. 2019;5(4):161–3. https://doi.org/10.1089/cren.2019.0059
-
6. Panah A, Masood J, Zaman F, Papatsoris AG, El-Husseiny T, Buchholz N. A technique to flush out renal stone fragments during percutaneous nephrolithotomy. J Endourol. 2009;23(1):5–6. https://doi.org/10.1089/end.2008.0296
-
7. Tepeler A, Resorlu B, Sahin T, Sarikaya S, Bayindir M, Oguz U, et al. Categorization of intraoperative ureteroscopy complications using modified Satava classification system. World J Urol. 2014;32(1):131–6. https://doi.org/10.1007/ s00345-013-1054-y
-
8. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13. https://doi.org/10.1097/01. sla.0000133083.54934.ae
-
9. Rukin NJ, Somani BK, Patterson J, Grey BR, Finch W, McClinton S, et al. Tips and tricks of ureteroscopy: consensus statement Part I. Basic ureteroscopy. Cent European J Urol. 2015;68(4):439–46. https://doi.org/10.5173/ ceju.2015.605a
-
10. Rukin NJ, Somani BK, Patterson J, Grey BR, Finch W, McClinton S, et al. Tips and tricks of ureteroscopy: consensus statement. Part II. Advanced ureteroscopy. Cent European J Urol. 2016;69(1):98–104. https://doi.org/10.5173/ ceju.2016.605b
-
11. Savun M, Korkmaz E, Atar FA, Özdemir H, Keskin ET, Şimşek A, et al. Flush out technique for retrieving stone fragments in distal ureteral stones. Presented at: 7th Urolithiasis Days; 2022 Dec 2–3; İstanbul, Türkiye.
-
12. Schatloff O, Lindner U, Ramon J, Winkler HZ. Randomized trial of stone fragment active retrieval versus spontaneous passage during holmium laser lithotripsy for ureteral stones. J Urol. 2010;183(3):1031–5. https://doi. org/10.1016/j.juro.2009.11.013
-
13. Chugh S, Pietropaolo A, Montanari E, Sarica K, Somani BK. Predictors of Urinary Infections and Urosepsis After Ureteroscopy for Stone Disease: a Systematic Review from EAU Section of Urolithiasis (EULIS). Curr Urol Rep. 2020;21(4):16. https://doi.org/10.1007/s11934-020-0969-2
-
14. Sevinc C, Balaban M, Ozkaptan O, Yucetas U, Karadeniz T. The management of total avulsion of the ureter from both ends: Our experience and literature review. Arch Ital Urol Androl. 2016;88(2):97–100. https://doi.org/10.4081/ aiua.2016.2.97
-
15. de la Rosette JJ, Skrekas T, Segura JW. Handling and prevention of complications in stone basketing. Eur Urol. 2006;50(5):991–8; discussion 998–9. https://doi.org/10.1016/j.eururo.2006.02.033
Comparison of the Flush-out Technique and the Basket for Retrieving Stone Fragments in Distal Ureteral Stones After Ureterolithotripsy: A Prospective Randomized Study
Yıl 2025,
Cilt: 17 Sayı: 3, 157 - 163, 30.09.2025
Metin Savun
,
Ertuğrul Arıkız
,
Harun Özdemir
,
Emin Taha Keskin
,
Murat Şahan
,
Halil Lütfi Canat
Öz
Objective: This prospective randomized study evaluated the efficacy and safety of the flush-out technique in comparison with conventional basket retrieval for the clearance of stone fragments during semi-rigid ureteroscopy in patients with distal ureteral stones.
Materials and Methods: Eighty-four patients diagnosed with distal ureteral stones were randomly assigned to two equal groups. Group 1 underwent stone retrieval using a nitinol basket. In contrast, group 2 was treated with the flush-out technique, which entails passive fragment expulsion facilitated by irrigation pressure and strategic withdrawal of the ureteroscope. Demographic data, stone characteristics, operative outcomes, and complication rates were recorded.
Results: Demographic data and stone characteristics were comparable between the two groups. The Group 2 exhibited a significantly reduced median operation time (30 vs. 45 minutes, p=0.020) and stone retrieval time (1 vs. 10 minutes, p=0.001) in comparison to the Group 1. The stone-free rates on postoperative day one were similar between the groups (97.6% vs. 100%, p=1.000). Intraoperative and postoperative complication rates were analogous, with no significant differences observed in the distribution of the Satava and Clavien-Dindo classifications.
Conclusion: The flush-out technique is a safe and efficacious alternative to basket retrieval for managing distal ureteral stones, yielding comparable clinical outcomes while reducing both operative and stone retrieval times. Its simplicity and cost-effectiveness may facilitate broader adoption in routine urological practice, particularly in high-volume and resource-constrained settings.
Etik Beyan
This prospective, randomized study was conducted in accordance with the principles outlined in the Declaration of Helsinki by the World Medical Association, titled "Ethical Principles for Medical Research Involving Human Subjects." Başakşehir Çam and Sakura City Hospital Clinical Research Ethics Committee Date: December 29, 2021 Decision No: 287.
Destekleyen Kurum
The authors did not receive support from any organization for the submitted work.
Kaynakça
-
1. Skolarikos A, Jung H, Neisius A, Petrik A, Kamphuis GM, Davis NF, et al. European Association of Urology Guidelines on Urolithiasis. Arnhem, The Netherlands: EAU Guidelines Office; 2025. ISBN: 978-94-92671-29-5. Available from: https://uroweb.org/guidelines
-
2. Khoder WY, Bader M, Sroka R, Stief C, Waidelich R. Efficacy and safety of Ho:YAG laser lithotripsy for ureteroscopic removal of proximal and distal ureteral calculi. BMC Urol. 2014;14:62. https://doi.org/10.1186/1471-2490-14-62
-
3. Matlaga BR, Chew B, Eisner B, Humphreys M, Knudsen B, Krambeck A, et al. Ureteroscopic Laser Lithotripsy: A Review of Dusting vs Fragmentation with Extraction. J Endourol. 2018;32(1):1–6. https://doi.org/10.1089/end.2017.0641
-
4. Santiago JE, Hollander AB, Soni SD, Link RE, Mayer WA. To Dust or Not To Dust: a Systematic Review of Ureteroscopic Laser Lithotripsy Techniques. Curr Urol Rep. 2017;18(4):32. https://doi.org/10.1007/s11934-017-0677-8
-
5. Tapiero S, Ghamarian P, Clayman R. A Technique to Flush Out Stone Fragments Through a Ureteral Access Sheath During Retrograde Intrarenal Surgery. J Endourol Case Rep. 2019;5(4):161–3. https://doi.org/10.1089/cren.2019.0059
-
6. Panah A, Masood J, Zaman F, Papatsoris AG, El-Husseiny T, Buchholz N. A technique to flush out renal stone fragments during percutaneous nephrolithotomy. J Endourol. 2009;23(1):5–6. https://doi.org/10.1089/end.2008.0296
-
7. Tepeler A, Resorlu B, Sahin T, Sarikaya S, Bayindir M, Oguz U, et al. Categorization of intraoperative ureteroscopy complications using modified Satava classification system. World J Urol. 2014;32(1):131–6. https://doi.org/10.1007/ s00345-013-1054-y
-
8. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004;240(2):205–13. https://doi.org/10.1097/01. sla.0000133083.54934.ae
-
9. Rukin NJ, Somani BK, Patterson J, Grey BR, Finch W, McClinton S, et al. Tips and tricks of ureteroscopy: consensus statement Part I. Basic ureteroscopy. Cent European J Urol. 2015;68(4):439–46. https://doi.org/10.5173/ ceju.2015.605a
-
10. Rukin NJ, Somani BK, Patterson J, Grey BR, Finch W, McClinton S, et al. Tips and tricks of ureteroscopy: consensus statement. Part II. Advanced ureteroscopy. Cent European J Urol. 2016;69(1):98–104. https://doi.org/10.5173/ ceju.2016.605b
-
11. Savun M, Korkmaz E, Atar FA, Özdemir H, Keskin ET, Şimşek A, et al. Flush out technique for retrieving stone fragments in distal ureteral stones. Presented at: 7th Urolithiasis Days; 2022 Dec 2–3; İstanbul, Türkiye.
-
12. Schatloff O, Lindner U, Ramon J, Winkler HZ. Randomized trial of stone fragment active retrieval versus spontaneous passage during holmium laser lithotripsy for ureteral stones. J Urol. 2010;183(3):1031–5. https://doi. org/10.1016/j.juro.2009.11.013
-
13. Chugh S, Pietropaolo A, Montanari E, Sarica K, Somani BK. Predictors of Urinary Infections and Urosepsis After Ureteroscopy for Stone Disease: a Systematic Review from EAU Section of Urolithiasis (EULIS). Curr Urol Rep. 2020;21(4):16. https://doi.org/10.1007/s11934-020-0969-2
-
14. Sevinc C, Balaban M, Ozkaptan O, Yucetas U, Karadeniz T. The management of total avulsion of the ureter from both ends: Our experience and literature review. Arch Ital Urol Androl. 2016;88(2):97–100. https://doi.org/10.4081/ aiua.2016.2.97
-
15. de la Rosette JJ, Skrekas T, Segura JW. Handling and prevention of complications in stone basketing. Eur Urol. 2006;50(5):991–8; discussion 998–9. https://doi.org/10.1016/j.eururo.2006.02.033