Inherited Diseases That Threaten Cattle Breeding

Öz

-

Anahtar Kelimeler

• Kalıtsal hastalıklar, moleküler mekanizma, sığır

Sığır Yetiştiriciliğini Tehdit Eden Kalıtsal Hastalıklar

Öz

Kalıtsal hastalıklar çiftlik hayvanlarında önemli verim ve ekonomik kayıplara sebep olan önemli bir hastalık grubudur. Kalıtsal hastalıkların moleküler mekanizmalarını anlamak, hastalıkları sürüden uzaklaştırmada önemli avantajlarsağlamaktadır. Hastalıkların gen düzeyinde moleküler tekniklerle teşhis yöntemlerine önem verilmesi ile kalıtsal hastalıklar ucuz ve pratik olarak teşhis edilirken ekonomik kayıplar azaltılabilir. Bu derlemede sığır kalıtsal hastalıkları hakkında bilgi vermek amaçlanmıştır

Anahtar Kelimeler

• Kalıtsal hastalıklar, moleküler mekanizma, sığır

Kaynakça

1. Ackermann MR, Kehril ME, Morfitt DC, 1993. Ventral dermatitis and vasculitis in a calf with bovine leukocyte adhesion deficiency. J Am Vet Med Assoc, 202: 413-415.
2. Agerholm S, Bendixen C, Andersen O, 2001. Arnbjerg malformation in Holstein calves. J Vet Diagn Invest, 13: 283–289. Complex vertebral
3. Agerholm JS, Bendixen C, Arnbjerg J, Andersen O, 2004. Morphological variation of “complex vertebral malformation” in Holstein calves. J Vet Diagn Invest, 16: 548–553.
4. Akyüz B, Kul BÇ, 2009. Türkiye’de Holştayn ırkı ineklerde üridin monofosfat senteaz eksikliğinin (DUMPS) belirlenmesi. Üniv Vet Fak Derg, 56: 231-232. Ankara
5. Akyüz B, Ertuğrul O, 2008. Türkiyede Holştsyan ve yerli sığırlarda üridin monofosfat senteaz eksikliğinin (DUMPS) belirlenmesi. Ankara Üniv Vet Fak Derg, 55: 57-60.
6. Akyüz B, Ertuğrul O, 2006. Detection of bovine leukocyte adhesion deficiency (BLAD) in Turkish native and Holstein cattle. Acta Vet Hung, 54: 173-178.
7. Andresen E, Basse A, Brummerstedt E, 1974. Lethal trait A 46 in cattle. Additional genetic investigations. Nord Vet Med, 26: 275-278.
8. Andresen E, Flagstad T, Basse A, 1970. Evidence of lethal trait A 46 in Black Pied Danish cattle of Friesian descent. Nord Vet Med, 22: 473-485.

9. Aprison MH, Daly EC, Shank RP, Mc Bride WJ, 1976. Neurochemical evidence for glycine as a transmitter and a model for its intra synaptosomal compartmentation. In metabolic compartmentation Anim Genet, 56: 37-63. neurotransmission.
10. Arthur PF, Renand G, Krauss D, 2001. Genetic and phenotypic relationships among different measures of growth and feed efficiency in young Charolais bulls. Lives Prod Sci, 68: 131–139.
11. Ayers J, Leipod HW, Padgett GA, 1988. Lession in Brangus cattle with chediak-higashi syndrome. Vet Pathol, 25: 432-436.
12. Başaran N, 1996. Tıbbi Genetik. Altıncı Baskı. İstanbul: Bilim Teknik Yayınevi, s. 49.
13. Batt CA, Wagner P, Wiedmann M, Luo J, Gilbert R, 1994. Detection of bovine leukocyte adhesion deficiency by nonisotopic ligase chain reaction. Anim Genet, 25: 95-98.
14. Berg T, Healy PJ, Tollersrud OK, Nilssen O, 1997. Molecular heterogeneity for bovine α- mannosidosis: detection of breed-specific mutations. Res Vet Sci, 63: 279–282. based assays for
15. Berg T, Tollersrud OK, Walkley SU, Siegel DA, Nilssen O, 1997. Purification of feline lysosomal a-mannosidase, determination of its cDNA sequence and identification of a mutation causing a-mannosidosis in Persian cats. Biochem J, 328: 863–870.
16. Brush PJ, Anderson PH, Gunning RF, 1987. The identification of factor XI deficiency in Holstein-Friesian cattle in Britain. Vet Rec, 121: 14–17.
17. Citek J, Rehout V, Hajkova J, Pavkova J, 2006. Monitoring of the genetic health of cattle in the Czech Republic. Vet Med Czech, 51(6): 333–339.
18. Citek J, Rehout V, Vecerek L, Hajkova J, 2007. Genotyping glycogen storage disease type II and type V in cattle reared in the Czech Republic. J Vet Med, 54: 257-259.
19. Craznik U, Grzybowski G, Kaminski S, Prusak B, Zabolewicz T, 2007. Effectiveness of a program aimed at the elimination of BLAD- carrier bulls from Polish Holstein-Fresien cattle. Vet Rec, 43: 56-70.
20. Curtis DR, Jhonston GAR, 1974. Amino acid transmitters in the mammalian central nervous system. Ergebn Physiol, 69: 97-189.
21. Dennis JA, Healy PJ, 1999. Definition of the mutation responsible for maple syrup urine disease in Poll Shorthorns and genotyping Poll Shorthorns and Poll Herefords for maple syrup urine disease alleles. Res Vet Sci, 67 (1): 1–6.
22. Dennis JA, Healy PJ, Beadudet AL, O’Brien WE, 1989. Molecular definition of bovine argininosuccinate synthase deficiency. Proc Natl Acad Sci, 86: 7947–7951.
23. Distl O, 2005. The use of molecular genetics in eliminating of inherited anomalies in cattle. Arch Tierz Dummerstorf, 48(3): 209-218.
24. El-Hamidi M, Leipold HW, Vestweber JG, Saperstein G, 1989. Spinal muscular atrophy on Brown Swiss calves. J Vet Med, 36: 731- 738.
25. Gentry PA, Black WD, 1980. Prevalence and inheritance thromboplastin antecedent) deficiency in cattle. J Dairy Sci, 63: 616-620. XI (plasma
26. Ghanem ME, Nakao T, Nishibori M, 2006. Deficiency syntheses (DUMPS) and X-chromosome deletion in fetal mummification in cattle. Anim Reprod Sci, 91: 45-54. monophosphate
27. Gilbert RO, Rebhun WC, Kim CA, Kehril ME, Schuster DE, Ackermann MR, 1993. Clinical manifestations deficiency in cattle: 14 cases (1977-1991). J Am Vet Med Assoc, 202: 445-449. adhesion
28. Grobet L, Martin RLJ, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A, Dunner S, Menissier F, Massabanda J, Fries R, Hanset R, Georges M, 1997. A deletion in the myostatin gene causes double-muscling in cattle. Nat Genet, 17: 71-74.
29. Grupe S, Dietle G, Schwerin M, 1996. Population survey of citrullinaemia on German Holsteins. Livest Prod Sci, 45: 35–38.
30. Gundlach AL, 1990. Disorder of the inhibitory glycine receptor inherited myoclonus in Poll Hereford calves. FASEB J, 4: 2761-2767.
31. Gutierrez JP, Canon JP, Goyache F, 1997. Estimation of direct and maternal genetic parameters for preweaning traits in the Asturiana de los Vallesbeef cattle breed through animal and sire models. J Anim Breed Genet, 114: 261-266.
32. Hanset R, Michaux C, 1985. On the genetic determinism of muscular hypertrophy in the Belgian White and Blue cattle breed. Genet Sel Evol, 17: 359-368.
33. Harper PA, Healy PJ, Dennis JA, Obrine JJ, Rayward DH, 1986. Citrullinaemia as a cause of death in neonatal Friesian calves. Aust Vet J, 63: 378.
34. Harper PAW, Walder KH, Healy PJ, 1988. Neurovisceral ceroid-lipofuscinosis in blind Devon cattle. Acta Neuropathol, 75: 632–636.
35. Healy PJ, 1996. Testing for undesirable traits in cattle: an Australian perspective. J Anim Sci, 74: 917–922.
36. Hirano T, Hirotsune S, Thomsen B, Horn P, Panitz F, Bendixen A, Petersen AH, Holm LE, Nielsen VH, Agerholm JS, Arnbjerg J, Bendixen C, 2006. A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N- acetylglucosamine complex vertebral malformation. Res, 16: 97-105. transporter causes Genome
37. Hocking JD, Jolly RD, Batt RD 1972. Deficiency of a-mannosidase in Angus cattle: an inherited lysosomal storage disease. Biochem J, 128: 69–78.
38. Houweling P, Cavanagh J, Palmer D, Frugier T,Mitchell NL, Windsor PA, Raadsma HW, Tammen lipofuscinosis in Devon cattle is caused by a single base duplication (c.662dupG) in the bovine CLN5 gene. Biochim Biophys Acta, 1762: 890–897. Neuronal ceroid
39. Inaba M, Yawata A, Koshino I, Sato K, Takeuchi M, Takakuwa Y, Manno S, Yawata Y, Kanzaki A, Sakai J, Ban A, Ono K, Maede Y, 1996. Defective anion transport and marked instability caused by hereditary total deficiency of red cell band 3 in cattle due to a nonsense mutation. J Clin Invest, 97: 1804-1817.
40. Inaba M, 2000. Red blood cell membrane defects. Feldman BF. Zinkl JG. Jain NC. eds. Schalm’s Philadelphia: Lippincott Williams & Wilkins, pp. 1012-1019. Hematology.
41. Jánosa Á, Baranyai B, Dohy J, 1999. Comparison of milk production of the progeny
42. Kalıtsal hastalıkların gösterdikleri klinik belirtilerin
43. hastalığa özgü olmaması nedeni ile klinik teşhis
44. yöntemleri yetersiz kalmaktadır. Ayrıca, kalıtsal
45. hastalıkların yayılmasında hastalıkların otozomal
46. çekinik olmalarından dolayı taşıyıcı bireyler önem
47. lidir. Çünkü hiçbir klinik belirti göstermeyen taşıyı
48. cıların genotiplerinde bulunan mutant allel, kullanı
49. lan suni tohumlama ve embriyo nakli ile çok kısa
50. sürede popülasyona yayabilmektedir.
51. Moleküler analiz yöntemleri kalıtsal hastalıkların
52. teşhisinde hızlı ve kesin sonuçlar vermesi nedeniy
53. le son derece önemlidir. Tüm bu veriler göz önüne
54. alınacak olursa henüz Türkiye’de kalıtsal hastalık
55. lar ile ilgili araştırmalara ve kalıtsal hastalıkların
56. sebep olabileceği ekonomik kayıplara gereken
57. önemin verilmediği ortaya çıkmaktadır. Hastalıkla
58. rın moleküler teknikler kullanılarak gen düzeyinde
59. teşhisine önem verilmesi ile kalıtsal hastalıklar
60. ucuz ve pratik olarak teşhis edilirken ekonomik
61. kayıplar da azaltılabilir. Damızlık olarak seçilen
62. hayvanların damızlık olarak kullanılmasından önce
63. o ırkta en sık görülen kalıtsal hastalıklar yönünden
64. taranması ve taşıyıcı olup/olmadıklarının belirlen
65. mesi gerekmektedir. Kaynaklar
66. Ackermann MR, Kehril ME, Morfitt DC, 1993. Ventral dermatitis and vasculitis in a calf with bovine leukocyte adhesion deficiency. J Am Vet Med Assoc, 202: 413-415.
67. Agerholm S, Bendixen C, Andersen O, 2001. Arnbjerg malformation in Holstein calves. J Vet Diagn Invest, 13: 283–289. Complex vertebral
68. Agerholm JS, Bendixen C, Arnbjerg J, Andersen O, 2004. Morphological variation of “complex vertebral malformation” in Holstein calves. J Vet Diagn Invest, 16: 548–553.
69. Akyüz B, Kul BÇ, 2009. Türkiye’de Holştayn ırkı ineklerde üridin monofosfat senteaz eksikliğinin (DUMPS) belirlenmesi. Üniv Vet Fak Derg, 56: 231-232. Ankara
70. Akyüz B, Ertuğrul O, 2008. Türkiyede Holştsyan ve yerli sığırlarda üridin monofosfat senteaz eksikliğinin (DUMPS) belirlenmesi. Ankara Üniv Vet Fak Derg, 55: 57-60.
71. Akyüz B, Ertuğrul O, 2006. Detection of bovine leukocyte adhesion deficiency (BLAD) in Turkish native and Holstein cattle. Acta Vet Hung, 54: 173-178.
72. Andresen E, Basse A, Brummerstedt E, 1974. Lethal trait A 46 in cattle. Additional genetic investigations. Nord Vet Med, 26: 275-278.
73. Andresen E, Flagstad T, Basse A, 1970. Evidence of lethal trait A 46 in Black Pied Danish cattle of Friesian descent. Nord Vet Med, 22: 473-485.
74. Aprison MH, Daly EC, Shank RP, Mc Bride WJ, 1976. Neurochemical evidence for glycine as a transmitter and a model for its intra synaptosomal compartmentation. In metabolic compartmentation Anim Genet, 56: 37-63. neurotransmission.
75. Arthur PF, Renand G, Krauss D, 2001. Genetic and phenotypic relationships among different measures of growth and feed efficiency in young Charolais bulls. Lives Prod Sci, 68: 131–139.
76. Ayers J, Leipod HW, Padgett GA, 1988. Lession in Brangus cattle with chediak-higashi syndrome. Vet Pathol, 25: 432-436.
77. Başaran N, 1996. Tıbbi Genetik. Altıncı Baskı. İstanbul: Bilim Teknik Yayınevi, s. 49.
78. Batt CA, Wagner P, Wiedmann M, Luo J, Gilbert R, 1994. Detection of bovine leukocyte adhesion deficiency by nonisotopic ligase chain reaction. Anim Genet, 25: 95-98.
79. Berg T, Healy PJ, Tollersrud OK, Nilssen O, 1997. Molecular heterogeneity for bovine α- mannosidosis: detection of breed-specific mutations. Res Vet Sci, 63: 279–282. based assays for
80. Berg T, Tollersrud OK, Walkley SU, Siegel DA, Nilssen O, 1997. Purification of feline lysosomal a-mannosidase, determination of its cDNA sequence and identification of a mutation causing a-mannosidosis in Persian cats. Biochem J, 328: 863–870.
81. Brush PJ, Anderson PH, Gunning RF, 1987. The identification of factor XI deficiency in Holstein-Friesian cattle in Britain. Vet Rec, 121: 14–17.
82. Citek J, Rehout V, Hajkova J, Pavkova J, 2006. Monitoring of the genetic health of cattle in the Czech Republic. Vet Med Czech, 51(6): 333–339.
83. Citek J, Rehout V, Vecerek L, Hajkova J, 2007. Genotyping glycogen storage disease type II and type V in cattle reared in the Czech Republic. J Vet Med, 54: 257-259.
84. Craznik U, Grzybowski G, Kaminski S, Prusak B, Zabolewicz T, 2007. Effectiveness of a program aimed at the elimination of BLAD- carrier bulls from Polish Holstein-Fresien cattle. Vet Rec, 43: 56-70.
85. Curtis DR, Jhonston GAR, 1974. Amino acid transmitters in the mammalian central nervous system. Ergebn Physiol, 69: 97-189.
86. Dennis JA, Healy PJ, 1999. Definition of the mutation responsible for maple syrup urine disease in Poll Shorthorns and genotyping Poll Shorthorns and Poll Herefords for maple syrup urine disease alleles. Res Vet Sci, 67 (1): 1–6.
87. Dennis JA, Healy PJ, Beadudet AL, O’Brien WE, 1989. Molecular definition of bovine argininosuccinate synthase deficiency. Proc Natl Acad Sci, 86: 7947–7951.
88. Distl O, 2005. The use of molecular genetics in eliminating of inherited anomalies in cattle. Arch Tierz Dummerstorf, 48(3): 209-218.
89. El-Hamidi M, Leipold HW, Vestweber JG, Saperstein G, 1989. Spinal muscular atrophy on Brown Swiss calves. J Vet Med, 36: 731- 738.
90. Gentry PA, Black WD, 1980. Prevalence and inheritance thromboplastin antecedent) deficiency in cattle. J Dairy Sci, 63: 616-620. XI (plasma
91. Ghanem ME, Nakao T, Nishibori M, 2006. Deficiency syntheses (DUMPS) and X-chromosome deletion in fetal mummification in cattle. Anim Reprod Sci, 91: 45-54. monophosphate
92. Gilbert RO, Rebhun WC, Kim CA, Kehril ME, Schuster DE, Ackermann MR, 1993. Clinical manifestations deficiency in cattle: 14 cases (1977-1991). J Am Vet Med Assoc, 202: 445-449. adhesion
93. Grobet L, Martin RLJ, Poncelet D, Pirottin D, Brouwers B, Riquet J, Schoeberlein A, Dunner S, Menissier F, Massabanda J, Fries R, Hanset R, Georges M, 1997. A deletion in the myostatin gene causes double-muscling in cattle. Nat Genet, 17: 71-74.
94. Grupe S, Dietle G, Schwerin M, 1996. Population survey of citrullinaemia on German Holsteins. Livest Prod Sci, 45: 35–38.
95. Gundlach AL, 1990. Disorder of the inhibitory glycine receptor inherited myoclonus in Poll Hereford calves. FASEB J, 4: 2761-2767.
96. Gutierrez JP, Canon JP, Goyache F, 1997. Estimation of direct and maternal genetic parameters for preweaning traits in the Asturiana de los Vallesbeef cattle breed through animal and sire models. J Anim Breed Genet, 114: 261-266.
97. Hanset R, Michaux C, 1985. On the genetic determinism of muscular hypertrophy in the Belgian White and Blue cattle breed. Genet Sel Evol, 17: 359-368.
98. Harper PA, Healy PJ, Dennis JA, Obrine JJ, Rayward DH, 1986. Citrullinaemia as a cause of death in neonatal Friesian calves. Aust Vet J, 63: 378.
99. Harper PAW, Walder KH, Healy PJ, 1988. Neurovisceral ceroid-lipofuscinosis in blind Devon cattle. Acta Neuropathol, 75: 632–636.
100. Healy PJ, 1996. Testing for undesirable traits in cattle: an Australian perspective. J Anim Sci, 74: 917–922.
101. Hirano T, Hirotsune S, Thomsen B, Horn P, Panitz F, Bendixen A, Petersen AH, Holm LE, Nielsen VH, Agerholm JS, Arnbjerg J, Bendixen C, 2006. A missense mutation in the bovine SLC35A3 gene, encoding a UDP-N- acetylglucosamine complex vertebral malformation. Res, 16: 97-105. transporter causes Genome
102. Hocking JD, Jolly RD, Batt RD 1972. Deficiency of a-mannosidase in Angus cattle: an inherited lysosomal storage disease. Biochem J, 128: 69–78.
103. Houweling P, Cavanagh J, Palmer D, Frugier T,Mitchell NL, Windsor PA, Raadsma HW, Tammen lipofuscinosis in Devon cattle is caused by a single base duplication (c.662dupG) in the bovine CLN5 gene. Biochim Biophys Acta, 1762: 890–897. Neuronal ceroid
104. Inaba M, Yawata A, Koshino I, Sato K, Takeuchi M, Takakuwa Y, Manno S, Yawata Y, Kanzaki A, Sakai J, Ban A, Ono K, Maede Y, 1996. Defective anion transport and marked instability caused by hereditary total deficiency of red cell band 3 in cattle due to a nonsense mutation. J Clin Invest, 97: 1804-1817.
105. Inaba M, 2000. Red blood cell membrane defects. Feldman BF. Zinkl JG. Jain NC. eds. Schalm’s Philadelphia: Lippincott Williams & Wilkins, pp. 1012-1019. Hematology.
106. Jánosa Á, Baranyai B, Dohy J, 1999. Comparison of milk production of the progeny of BLAD-carrier and healthy Holstein bulls in Hungary. Acta Vet Hung, 47(3): 283-289.
107. Jhonstone AD, McSporran KD, Kenny JE, Anderson IL, MacPherson GR, Jolly RD, 2004. Myophosphorylase deficiency (glycogen storage disease Type V) in a herd of Charlolais cattle Conformation by PCR-RFLP testing. N Z Vet in J, 52(6): 404-408. New Zealand:
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