Serum Concentrations of Zinc, Copper, Manganese in Young Cattle with Dermatophytosis

Öz

This study aimed to evaluate serum zinc (Zn), copper (Cu) and manganese (Mn) levels in young cattle with dermatophytosis. Used in this study was a total of 36 Holstein young cattle between 4-18 month of age and different sex (12 male, 24 female) from the animal husbandry operations in and around Kayseri. Following the clinical examination, Group I (10 animals) served as noninfective controls. Cattle showing all clinical sings of dermatophytosis and diagnosed as dermatophytosis by mycological examination of samples taken at suitable conditions were served as Group II (26 animals). Median serum Zn, Cu and Mn levels were found 124, 129.8 and 68.4 µg/dl in Group I, respectively and median serum Zn, Cu and Mn levels were found 127, 122 and 68.5 µg/dl in Group II, respectively. No significant difference were observed between Group I and Group II in serum Zn, Cu and Mn levels (p>0.05). As a result of this study, it was determined that serum Zn, Cu and Mn levels were not influenced by dermatophytosis in young cattle. 

Anahtar Kelimeler

• Bakır
• çinko
• dermatofitozis
• mangan
• sığır
• T. verrucosum

Dermatofitozisli Genç Sığırlarda Serum Çinko, Bakır ve Mangan Seviyeleri

Öz

Bu çalışmada, dermatofitozisli genç sığırlarda serum çinko (Zn), bakır (Cu) ve mangan (Mn) seviyelerinin belirlenmesi amaçlanmıştır. Çalışmanın materyalini, Kayseri yöresinde bulunan hayvancılık işletmelerinden holştayn, heriki cinsiyetten (12 erkek ve 24 dişi) ve yaşları 4-18 aylık arasında değişen toplam 36 genç sığır kullanılmıştır. Hayvanlar, yapılan klinik muayenelere göre enfekte olmayan kontrol Grup I (10 adet) ve dermatofitozisin tüm klinik belirtilerinigösteren ve uygun koşullarda alınan numunelerin mikolojik incelemelerinde dermatofitozis olduğu tespit edilen Grup II(26 adet) olacak şekilde iki gruba ayrıldı. Çalışmaya alınan sağlıklı hayvanların kan serum Zn, Cu ve Mn seviyelerininmedian değerleri sırasıyla 124, 129.8 ve 68.4 µg/dl, dermatofitozisli hayvanların kan serum Zn, Cu ve Mn median değerleri sırasıyla 127, 122 ve 68.5 µg/dl olarak belirlendi. Her iki gruptaki kan serum Zn, Cu ve Mn seviyeleri arasında istatistiksel olarak herhangi bir fark bulunamadı (p>0.05). Sonuç olarak; genç dermatofitozisli sığırlarda serum Zn, Cuve Mn seviyelerinin etkilenmediği belirlendi

Anahtar Kelimeler

• Bakır
• çinko
• dermatofitozis
• mangan
• sığır
• T. verrucosum

Kaynakça

1. Al-Ani FK, Younes FA, Al-Rawasshden FO, 2002. Ringworm infection in cattle and horses in Jordan. Acta Veterinaria Brno, 71: 55-60.
2. Al-Qudah KM, Gharaibeh AA, Al-Shyyab MM, 2009. Trace minerals status and antioxidant enzymes dermatophytosis. Biol Trace Elem Res, doi. 10.1007/s12011-009-8525-4. calves with
3. Anindita D, Bhowmik MK, Biswas P, 2006. Dermatophytosis Trichophyton haemato-biochemical and pathomorphological changes. Indian J Vet Pathol, 30(2). due occurrence,
4. Arda M, 2000.Temel Mikrobiyoloji. Ankara: Medisan Yayınevi, p.333-335.
5. Caban˜es FJ, Abarca ML, Bragulat MR, 1997. Dermatophytes animals in Barcelona, Spain. Mycopathol, 137: 107–113. from domestic Mycopathol,
6. Colombini S, 1999. Canine zinc-responsive dermatosis. Vet Clin North Am Small Anim Pract, 29: 1373-1383.
7. Dilek N, Yücel AY, Dilek AR, Saral Y, Tora- man ZA, 2009. Fırat Üniversitesi Hastanesi Dermatoloji Kliniği’ne Başvuran Hastalardaki Dermatofitoz Etkenleri - Orijinal Araştırma. Turkish Journal of Dermatology, 3: 27-31
8. Gross KL, Wedekind KJ, Cowell CS, Schoenherr WD, Jewell DE, Zicker SC, Debraekeleer J, Frey RA, 2000. Nutrients. Hand MS. Tacther CD. Remillard RL. Roudebush P. eds. Small Animal Clinical Nutrition. Fourth Edition. Missouri: Walsworth Publishing Company, p. 21.

9. Gudding R, Lund A, 1995. Immunoprophylaxis of bovine dermatophytosis. Can Vet J, 36: 302-306.
10. Halley LD, Standard PG, 1973. Laboratory Methods in Medical Mycology.3th Ed. US Department of Health, Education and Welfare, Center of Disease Control, Atlanta, pp 41-57.
11. İmren HY, Şahal M, 1994. Trikofiti. Alaçam E. Şahal M. eds. Veteriner İç Hastalıkları. 3. bas- kı. Ankara: Medisan, pp. 213-215.
12. Karapehlivan M, Uzlu E, Kaya N, Kankavi O, Ural K, Citil M, 2007. Investigation of some biochemical parameters and the antioxidant system in calves with dermatophytosis. Turk J Vet Anim Sci, 31(2):85–89. 15. Khosravi AR, Mahmoudi M, 2003. Dermatophytes animals in Iran. Mycoses, 46(5-6): 222-225. from domestic
13. Kırmızıgül AH, Gökçe E, Özyıldız Z, Büyük F, Şahin M, 2009. Sığırlarda dermatofitozis teda- visinde enilconazole’ün (%10) topikal kullanı- mı: klinik, mikolojik ve histopatolojik bulgular. Kafkas Univ Vet Fak Derg,15 (2): 273-277.
14. Koçoğlu E, Karabay O, Kırmusaoğlu S, 2007. Yüzeyel mantar etkeni olarak izole edilen mantarlar: iki yıllık verilerin değerlendirilmesi. Klimik XIII. Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Kongresi, p.296
15. Kojouri GA, Ebrahimi A, Zaheri M, 2009. Zinc and selenium dermatophytosis. Comp Clin Pathol, 18:283- 286. in cows with
16. Medleau L, Ristic Z, White-Weithers NE, 1993. Fungal Dermatoses. Howard JL. Ed. Current Veterinary Therapy 3 & Food Animal Practice. Company, pp. 890-894. WB Saunders
17. Moriello KA, 2001. Diagnostic techniques for dermotophytes. Clin Tech Small Anim Pract, 16: 219-224.
18. Nevoralova Z, 2006. transmitted from animals. Cas Lek Cesk, 145: 959-963. Dermatophytoses
19. Nisbet C, Yarim GF, Ciftci G, Arslan HH, Ciftci A, 2006. Effects of trichophytosis on serum zinc levels in calves. Biol Trace Elem Res, 113: 273-280.
20. Norris D, (1985). Zinc and cutaneous inflammation. Arch Dermatol, 121: 985.
21. Or E, Bakırel U, 2002. Dermatomikozis. Gül Y, ed. Geviş Getiren Hayvanların İç Hastalıkları. Ankara: Özkan Matbaacılık Ltd. Şti., pp. 385- 386.
22. Or ME, Bakırel U, Tuncel H, Arun S, Karakoç Y, Dodurka HT, Barutçu ÜB, 2002. Deri hasta- lıklı köpeklerde serum çinko ve bakır düzeyleri ile histopatolojik değişikliklerin ilişkisi. İstanbul Üniv Vet Fak Derg, 28(2): 337-345.
23. Papini R, Nardoni S, Fanelli A, Mancianti F, 2009. High infection rate of Trichophyton verrucosum in calves from central Italy. Zoonoses Public Health, 56(2): 59-64.
24. Scott DW, Miller WH, Griffin CE, eds., 1995. Muller&Kirk’s Small Animal Dermatology. Fifth Edition. Philadelphia: WB Saunders Company, p. 890.
25. Songer JG, Post KW, 2005. Veterinary Microbiology. Missouri: Elsevier, p.360-365.
26. Stockdale PM, 1953. Nutritional requirements of the dermatophytes. Biol Rev, 28(1): 84-104.
27. Takatori K, Takahashi A, Kawai S, Ichijo S, Hasegawa A, 1993. Isolation of Trichophyton verrucosum from lesional and non-lesional skin in calves. J Vet Med Sci. 55: 343-344.
28. Ural K, Karakurum MÇ, Duru Ö, Cıngı CÇ, Haydardedeoğlu AE, 2009. Serum zinc concentrations in dogs with canis dermatophytosis: a pilot study. Turk J Vet Anim Sci, 33(4): 279-283 Microsporum
29. Wabacha JK, Gitau GK, Bebora LC, Bwanga CO, Wamuri ZM, Mbithi PM, 1998. Occurence of Trichophyton verrucosum in dairy calves and its spread to animal attendants. J S Afr Vet Assoc, 69: 172-183. (ringworm) due to
30. Watson TDG, 1998. Diet and skin diseases in dogs and cats. J Nutr, 128(12): 2783-2789.
31. Weber A, 2000. Mycozoonoses with special regard to ringworm of cattle. Mycoses, 43: 20- 22.
32. White SD, Bourdeau P, Rosychuk RA, Cohen B, Bonenberger T, Fieseler KV, Ihrke P, Chapman PL, Schultheiss P, Zur G, Cannon A, Outerbridge C, 2001. Zinc-responsive dermatosis in dogs: 41 cases and literature review. Vet Dermatol, 12(2):101-109.
33. Al-Ani FK, Younes FA, Al-Rawasshden FO, 2002. Ringworm infection in cattle and horses in Jordan. Acta Veterinaria Brno, 71: 55-60.
34. Al-Qudah KM, Gharaibeh AA, Al-Shyyab MM, 2009. Trace minerals status and antioxidant enzymes dermatophytosis. Biol Trace Elem Res, doi. 10.1007/s12011-009-8525-4. calves with
35. Anindita D, Bhowmik MK, Biswas P, 2006. Dermatophytosis Trichophyton haemato-biochemical and pathomorphological changes. Indian J Vet Pathol, 30(2). due occurrence,
36. Arda M, 2000.Temel Mikrobiyoloji. Ankara: Medisan Yayınevi, p.333-335.
37. Caban˜es FJ, Abarca ML, Bragulat MR, 1997. Dermatophytes animals in Barcelona, Spain. Mycopathol, 137: 107–113. from domestic Mycopathol,
38. Colombini S, 1999. Canine zinc-responsive dermatosis. Vet Clin North Am Small Anim Pract, 29: 1373-1383.
39. Dilek N, Yücel AY, Dilek AR, Saral Y, Tora- man ZA, 2009. Fırat Üniversitesi Hastanesi Dermatoloji Kliniği’ne Başvuran Hastalardaki Dermatofitoz Etkenleri - Orijinal Araştırma. Turkish Journal of Dermatology, 3: 27-31
40. Gross KL, Wedekind KJ, Cowell CS, Schoenherr WD, Jewell DE, Zicker SC, Debraekeleer J, Frey RA, 2000. Nutrients. Hand MS. Tacther CD. Remillard RL. Roudebush P. eds. Small Animal Clinical Nutrition. Fourth Edition. Missouri: Walsworth Publishing Company, p. 21.
41. Gudding R, Lund A, 1995. Immunoprophylaxis of bovine dermatophytosis. Can Vet J, 36: 302-306.
42. Halley LD, Standard PG, 1973. Laboratory Methods in Medical Mycology.3th Ed. US Department of Health, Education and Welfare, Center of Disease Control, Atlanta, pp 41-57.
43. İmren HY, Şahal M, 1994. Trikofiti. Alaçam E. Şahal M. eds. Veteriner İç Hastalıkları. 3. bas- kı. Ankara: Medisan, pp. 213-215.
44. Karapehlivan M, Uzlu E, Kaya N, Kankavi O, Ural K, Citil M, 2007. Investigation of some biochemical parameters and the antioxidant system in calves with dermatophytosis. Turk J Vet Anim Sci, 31(2):85–89. 15. Khosravi AR, Mahmoudi M, 2003. Dermatophytes animals in Iran. Mycoses, 46(5-6): 222-225. from domestic
45. Kırmızıgül AH, Gökçe E, Özyıldız Z, Büyük F, Şahin M, 2009. Sığırlarda dermatofitozis teda- visinde enilconazole’ün (%10) topikal kullanı- mı: klinik, mikolojik ve histopatolojik bulgular. Kafkas Univ Vet Fak Derg,15 (2): 273-277.
46. Koçoğlu E, Karabay O, Kırmusaoğlu S, 2007. Yüzeyel mantar etkeni olarak izole edilen mantarlar: iki yıllık verilerin değerlendirilmesi. Klimik XIII. Türk Klinik Mikrobiyoloji ve İnfeksiyon Hastalıkları Kongresi, p.296
47. Kojouri GA, Ebrahimi A, Zaheri M, 2009. Zinc and selenium dermatophytosis. Comp Clin Pathol, 18:283- 286. in cows with
48. Medleau L, Ristic Z, White-Weithers NE, 1993. Fungal Dermatoses. Howard JL. Ed. Current Veterinary Therapy 3 & Food Animal Practice. Company, pp. 890-894. WB Saunders
49. Moriello KA, 2001. Diagnostic techniques for dermotophytes. Clin Tech Small Anim Pract, 16: 219-224. 21. Nevoralova Z,
50. Dermatophytoses
51. transmitted from animals. Cas Lek Cesk, 145: 959-963.
52. Nisbet C, Yarim GF, Ciftci G, Arslan HH, Ciftci A, 2006. Effects of trichophytosis on serum zinc levels in calves. Biol Trace Elem Res, 113: 273-280.
53. Norris D, (1985). Zinc and cutaneous inflammation. Arch Dermatol, 121: 985.
54. Or E, Bakırel U, 2002. Dermatomikozis. Gül Y, ed. Geviş Getiren Hayvanların İç Hastalıkları. Ankara: Özkan Matbaacılık Ltd. Şti., pp. 385- 386.
55. Or ME, Bakırel U, Tuncel H, Arun S, Karakoç Y, Dodurka HT, Barutçu ÜB, 2002. Deri hasta- lıklı köpeklerde serum çinko ve bakır düzeyleri ile histopatolojik değişikliklerin ilişkisi. İstanbul Üniv Vet Fak Derg, 28(2): 337-345.
56. Papini R, Nardoni S, Fanelli A, Mancianti F, 2009. High infection rate of Trichophyton verrucosum in calves from central Italy. Zoonoses Public Health, 56(2): 59-64.
57. Scott DW, Miller WH, Griffin CE, eds., 1995. Muller&Kirk’s Small Animal Dermatology. Fifth Edition. Philadelphia: WB Saunders Company, p. 890.
58. Songer JG, Post KW, 2005. Veterinary Microbiology. Missouri: Elsevier, p.360-365.
59. Stockdale PM, 1953. Nutritional requirements of the dermatophytes. Biol Rev, 28(1): 84-104.
60. Takatori K, Takahashi A, Kawai S, Ichijo S, Hasegawa A, 1993. Isolation of Trichophyton verrucosum from lesional and non-lesional skin in calves. J Vet Med Sci. 55: 343-344.
61. Ural K, Karakurum MÇ, Duru Ö, Cıngı CÇ, Haydardedeoğlu AE, 2009. Serum zinc concentrations in dogs with canis dermatophytosis: a pilot study. Turk J Vet Anim Sci, 33(4): 279-283 Microsporum
62. Wabacha JK, Gitau GK, Bebora LC, Bwanga CO, Wamuri ZM, Mbithi PM, 1998. Occurence of Trichophyton verrucosum in dairy calves and its spread to animal attendants. J S Afr Vet Assoc, 69: 172-183. (ringworm) due to
63. Watson TDG, 1998. Diet and skin diseases in dogs and cats. J Nutr, 128(12): 2783-2789.
64. Weber A, 2000. Mycozoonoses with special regard to ringworm of cattle. Mycoses, 43: 20- 22.
65. White SD, Bourdeau P, Rosychuk RA, Cohen B, Bonenberger T, Fieseler KV, Ihrke P, Chapman PL, Schultheiss P, Zur G, Cannon A, Outerbridge C, 2001. Zinc-responsive dermatosis in dogs: 41 cases and literature review. Vet Dermatol, 12(2):101-109.