Japon Bıldırcınlarda (Coturnix Coturnix Japonica) Xylazine-Ketamine ve Medetomidine-Ketamine Anestezisinin Klinik Olarak Karşılaştırmalı Değerlendirilmesi
Yıl 2017,
Cilt: 14 Sayı: 3, 169 - 176, 15.12.2017
Mustafa Barış Akgül
Nihat Şındak
,
Ali Gülaydın
,
Doğukan Özen
Öz
Bu çalışmanın amacı bıldırcınlarda xylazine-ketamine ve medetomidine-ketamine kombinasyonlarının kullanımı-nı klinik parametreleri izleyerek karşılaştırmaktır. Çalışma, klinik olarak sağlıklı ve yetişkin olan 20 adet Japon bıldırcını her grupta 10 adet olacak şekilde iki gruba ayrılmıştır. Xylazine-Ketamine grubuna (n=10) 8mg/kg Xylazine HCl ve 50mg/kg Ketamine HCl kombinasyonu intramusküler (IM) olarak verildi. Medetomidine-Ketamine grubuna (n=10) ise 0.1ml/kg Medetomidine ve 50 mg/kg Ketamine HCl kombinasyonu intramusküler (IM) yolla verildi. Her bir hayvan moni-törize edilerek kalp atım sayısı, solunum sayısı, kloakal ısı değerleri kayıt edildi. MK grubunun anesteziye girme süresi XK grubuna göre daha hızlı iken, uyanma süreleri bakımından XK grubunda daha kısa sürede oluştuğu gözlendi. Her iki grupta da kalp frekansının zaman içerisinde yükselmiş, solunum sayısı ve kloakal ısı ise zaman içerisinde azalmıştır ve bu değişim istatistiksel açıdan anlamlı bulunmuştur (p<0.001). Sonuç olarak her iki grupta da uygulanan anestezi protokolünün inhalasyon anestezisi uygulanması mümkün olmayan koşullar altında, bıldırcınlarda ve diğer kanatlı türle-rinde çalışmanın konusu olan anestezik kombinasyonların güvenli ve etkin sonuçlarından dolayı kullanılabileceği sonu-cuna varılmıştır.
Kaynakça
- 1. Bennett RA. Basic anesthesia and surgery in avian patients. Proceedings of the North American Veterinary Conference. January, 16-21, 1993; Orlando-USA.
2. Coles BH. Anaesthesia. Essentials of Avian Medicine and Surgery. Third Edition. Oxford: Blackwell Publishing, 2007; p. 133- 5.
3. Curro TG. Anesthesia of pet birds. JEPM 1998; 7(1): 11- 4.
4. Durrani UF, Ashraf M, Khalid A. Comparative efficacy of detomidine and detomidine-ketamine cocktail in quails. Pakistan Vet J 2005; 25(4): 197- 9.
5. Durrani UF, Khan MA, Ahmad SS. Compara-tive efficacy (sedative and anaesthetic) of detomidine, ketamine and detomidine-ketamine cock tail in pigeons (Columba livia). Pakistan Vet J 2008; 28(3): 115- 8.
6. Durrani UF, Ashraf M, Khan MA. A compari-son of the clinical effects associated with xylazine, ketamine, and a xylazine-ketamine cocktail in pigeons (Columba livia). Turk J Vet Anim Sci 2009; 33(5): 413- 7.
7. Gunkel C, Lafortune M. Current Techniques in Avian Anesthesia. JEPM 2005; 14(4): 263- 76.
8. Hoffman PE. Clinical evaluation of xylazine as a chemical restraining agent, sedative and analgesic in horses. J Am Vet Med As-soc 1974; 164(1): 42- 5.
9. Kamiloglu A, Yayla S, Kamiloglu NN, Ozay-
din I, Kurt B. Clinical evaluation of intramus-cular and intraosseous xylazine-ketamine anesthesia in quails (Coturnix coturnix japo-nica). Erciyes Üniv Vet Fak Derg 2014; 11(3): 169- 74.
10.Kılıç N, Paşa S. Cardiopulmonary effects of propofol compared with those of a medeto-midine-ketamine combination in the common buzzards (Buteo buteo). Revue Med Vet 2009; 160(3): 154- 9.
11.Kılıç N. A Comparison between medetomidi-ne-ketamine and xylazine-ketamine anaest-hesia in rabbits. Turk J Vet Anim Sci 2004; 28: 921- 6.
12.Lierz M, Korbel R. Anesthesıa and analgesia in birds. JEPM 2012; 21(1): 44-58.
13.Moghadam AZ, Sadegh AB, Sharifi S, Habi-bian S. Comparison of intranasal administra-tion of diazepam, midazolam and xylazine in pigeons: Clinical evaluation. IJVST 2009; 1(1): 19-26.
14.Salonen JS. Pharmacokinetics of detomidi-ne. Acta Vet Scand Suppl 1986; 82: 59- 66.
15.Valverde A, Bienzle D, Smith DA, Valliant AE. Intraosseous cannulation and drug admi-nistration for induction of anesthesia in chic-kens. Vet Surg 1993; 22(3): 240- 4.
16.Yayla S, Kamiloğlu NN, Kamiloğlu A, Özay-dın İ, Ermutlu CŞ. Comparison of the effects of ıntramuscular and ıntraosseal administra-tion of detomidine/ ketamine combination for general anaesthesia in quails (Coturnix coturnix japonica). Bulg J Agric Sci 2015; 21(1): 220- 4.
17.Yayla S, Kamiloglu N, Kamiloglu A, Ozaydin I. Comparision of intravenous and intraosse-ous administration of propofol-ketamine com-bination for anesthesia in quails (Coturnix coturnix japonica). Kocatepe Vet J 2014; 7(1): 11- 6.
Clinical Evaluation of Xylazine-Ketamine and Medetomidine-Ketamine Anesthesia in Japanese Quails (Coturnix coturnix japonica)
Yıl 2017,
Cilt: 14 Sayı: 3, 169 - 176, 15.12.2017
Mustafa Barış Akgül
Nihat Şındak
,
Ali Gülaydın
,
Doğukan Özen
Öz
The aim of this study was to compare the use of xylazine-ketamine and medetomidine-ketamine combina-tions in quails by monitoring clinical parameters. In the study, 20 japanese quail that were clinically healthy and adult were divided into two groups of 10 in each group. The combination of 8mg/kg Xylazine HCl and 50mg/kg Ketamine HCl in the Xylazine-Ketamine (XK) group (n=10) was given intramuscularly (IM). In the Medetomidine-ketamine (MK) group (n=10), the combination of 0.1ml/kg Medetomidine and 50mg/kg Ketamine HCl was administered intramuscularly (IM). Each animal was monitored and the heart rate, respiratory rate, cloacal temperature values were recorded. Medetomi-dine-ketamine (MK) group sedation time was faster than the xylazine-ketamine (XK) group while in terms of recovery time it was observed to occur in a shorter time than the XK group. Both groups heart rates were increase but respirato-ry rates and cloacal heat were decrease in time and it is a significant difference (P<0.001). As a result of the implemen-tation of inhalation anesthesia in impossible conditions in quail and other avian species, both groups also concluded that anesthetic combinations protocol used in anesthesia was safe and effective.
Kaynakça
- 1. Bennett RA. Basic anesthesia and surgery in avian patients. Proceedings of the North American Veterinary Conference. January, 16-21, 1993; Orlando-USA.
2. Coles BH. Anaesthesia. Essentials of Avian Medicine and Surgery. Third Edition. Oxford: Blackwell Publishing, 2007; p. 133- 5.
3. Curro TG. Anesthesia of pet birds. JEPM 1998; 7(1): 11- 4.
4. Durrani UF, Ashraf M, Khalid A. Comparative efficacy of detomidine and detomidine-ketamine cocktail in quails. Pakistan Vet J 2005; 25(4): 197- 9.
5. Durrani UF, Khan MA, Ahmad SS. Compara-tive efficacy (sedative and anaesthetic) of detomidine, ketamine and detomidine-ketamine cock tail in pigeons (Columba livia). Pakistan Vet J 2008; 28(3): 115- 8.
6. Durrani UF, Ashraf M, Khan MA. A compari-son of the clinical effects associated with xylazine, ketamine, and a xylazine-ketamine cocktail in pigeons (Columba livia). Turk J Vet Anim Sci 2009; 33(5): 413- 7.
7. Gunkel C, Lafortune M. Current Techniques in Avian Anesthesia. JEPM 2005; 14(4): 263- 76.
8. Hoffman PE. Clinical evaluation of xylazine as a chemical restraining agent, sedative and analgesic in horses. J Am Vet Med As-soc 1974; 164(1): 42- 5.
9. Kamiloglu A, Yayla S, Kamiloglu NN, Ozay-
din I, Kurt B. Clinical evaluation of intramus-cular and intraosseous xylazine-ketamine anesthesia in quails (Coturnix coturnix japo-nica). Erciyes Üniv Vet Fak Derg 2014; 11(3): 169- 74.
10.Kılıç N, Paşa S. Cardiopulmonary effects of propofol compared with those of a medeto-midine-ketamine combination in the common buzzards (Buteo buteo). Revue Med Vet 2009; 160(3): 154- 9.
11.Kılıç N. A Comparison between medetomidi-ne-ketamine and xylazine-ketamine anaest-hesia in rabbits. Turk J Vet Anim Sci 2004; 28: 921- 6.
12.Lierz M, Korbel R. Anesthesıa and analgesia in birds. JEPM 2012; 21(1): 44-58.
13.Moghadam AZ, Sadegh AB, Sharifi S, Habi-bian S. Comparison of intranasal administra-tion of diazepam, midazolam and xylazine in pigeons: Clinical evaluation. IJVST 2009; 1(1): 19-26.
14.Salonen JS. Pharmacokinetics of detomidi-ne. Acta Vet Scand Suppl 1986; 82: 59- 66.
15.Valverde A, Bienzle D, Smith DA, Valliant AE. Intraosseous cannulation and drug admi-nistration for induction of anesthesia in chic-kens. Vet Surg 1993; 22(3): 240- 4.
16.Yayla S, Kamiloğlu NN, Kamiloğlu A, Özay-dın İ, Ermutlu CŞ. Comparison of the effects of ıntramuscular and ıntraosseal administra-tion of detomidine/ ketamine combination for general anaesthesia in quails (Coturnix coturnix japonica). Bulg J Agric Sci 2015; 21(1): 220- 4.
17.Yayla S, Kamiloglu N, Kamiloglu A, Ozaydin I. Comparision of intravenous and intraosse-ous administration of propofol-ketamine com-bination for anesthesia in quails (Coturnix coturnix japonica). Kocatepe Vet J 2014; 7(1): 11- 6.