Araştırma Makalesi
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Köpeklerde Oral Kavitedeki Patolojik Lezyonlarının Retrospektif Değerlendirilmesi

Yıl 2022, Cilt: 19 Sayı: 2, 129 - 135, 01.08.2022
https://doi.org/10.32707/ercivet.1142611

Öz

Köpeklerde oral neoplaziler ve neoplastik olmayan lezyonlar sıklıkla karşılaşılan patolojilerdir. Bu lezyonların histo-patolojik incelemesi tanı koymak ve klinisyen hekimleri uygun tedaviye yönlendirmek için gereklidir. Bu çalışmada, köpeklerin ağız boşluğunda yaygın olarak gözlenen patolojik lezyonları retrospektif olarak belgelemek amaçlandı. Bu kapsamda 2010-2020 yılları arasında farklı ırk, cinsiyet ve yaş gruplarındaki köpeklerde 167 oral patoloji vakası ince-lendi. Oral patolojiler hematoksilen ve eozin boyama yöntemi ile teşhis edilen histopatolojik özelliklere göre neoplastik (benign ve malign neoplazmalar) ve neoplastik olmayan lezyonlar olarak sınıflandırıldı. Bulgularda malign (%46.10; 77/167) ve iyi huylu neoplazmların (%40.11; 67/167) baskın olduğu, ancak neoplastik olmayan lezyonların (%13.77; 23/167) kısıtlı olduğu tespit edildi. En sık görülen malign neoplazm, malign melanom (%50.64; 39/77) iken, odontojenik neoplazmlar en sık görülen benign neoplazmlar olarak belirlendi (%74.62; 50/67). Etkilenen hasta profilleri değerlendi-rildiğinde, erkeklerin oral patolojilere daha yatkın olduğunu (E/D: %62.87/%35.32; 105/59), en çok etkilenen yaşam evresinin ileri yaş (%79.48; 31/39) olduğu ve büyük safkan köpeklerin en sık rastlanan köpek ırkları (%49.10; 82/167) olduğu, bunu karma ırkların (%19.76; 33/167) izlediği tespit edildi. Bu bulgular ki-kare testi ile istatistiksel olarak anlamlı farklılıklar gösterdi. Ayrıca oral kavitede en sık etkilenen bölgenin dişeti olduğu (%30.76; 12/39) bulundu. Sonuç olarak, bu çalışma cinsiyet, yaş, cins ve etkilenen bölge açısından en sık görülen oral patolojiler hakkında literatür bilgisine katkı sağlamaktadır.

Kaynakça

  • Bergman PJ.Canine oral melanoma. Clin Tech Small Anim Pract 2007; 22(2): 55-60.
  • Bonfanti U,Bertazzolo W,Gracis M,Roccabianca P, Romanelli G, Palermo G, Zini E. Diagnostic value of cytological analysis of tumours and tumour-like lesions of the oral cavity in dogs and cats: A pro-spective study on 114 cases. Vet J 2015; 205(2): 322-7.
  • Brønden LB, Eriksen T, Kristensen AT. Oral malig-nant melanomas and other head and neck neo-plasms in Danish dogs-data from the Danish Vet-erinary Cancer Registry. Acta Vet Scand 2009; 51(1): 1-6.
  • Cray M, Selmic LE, Ruple A. Demographics of dogs and cats with oral tumors presenting to teaching hospitals: 1996-2017. J Vet Sci 2020; 21: 5.
  • Creevy KE, Grady J, Little SE, Little SE, Moore GE, Strickler BG, Thompson S, Webb JA. 2019 AAHA canine life stage guidelines. J Am Anim Hosp Assoc 2019; 55(6): 267-90.
  • Fiani N, Verstraete FJ, Kass PH, Cox DP. Clinico-pathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995-2005). J Am Vet Med Assoc 2011; 238(4): 495-500.
  • Fulton A, Arzi B, Murphy B, Naydan DK, Verstraete FJ. The expression of calretinin and cytokeratins in canine acanthomatous ameloblastoma and oral squamous cell carcinoma. Vet Comp Oncol 2014; 12(4): 258-65.
  • Goldschmidt MH. Benign and malignant melanocytic neoplasms of domestic animals. Am J Dermato-pathol 1985;7: 203-12.
  • Head KW, Cullen JM, Dubielzig RR, Else WR, Mis-drop W, Patnaik AK, Tateyama S, Van der Gaag I. Histological classification of tumors of the alimentary system in domestic animals. In: WHO International Histological Classification of Tumors of Domestic Animals Armed Forces Institute of Pathology, American Registry of Pathology. Second Edition. Washington: World Health Organization, 2003; pp. 29-57.
  • Lange CE, Favrot C. Canine papillomaviruses. Vet Clin Small Anim 2011; 41(6): 1183-95.
  • Liptak JM, Withrow SJ. Oral tumours. Withrow SJ. Vail DM. eds. In: Withrow &Mac Ewen’s Small Animal Clinical Oncology. Philadelphia: Elsevier Saunders, 2013; pp. 381-98.
  • Lommer MJ. Oral inflammation in small animals. Vet Clin Small Anim 2013; 43(3): 555-71.
  • Mikiewicz M, Paździor-Czapula K, Gesek M, Lemi-shevskyi V, Otrocka-Domagała I. Canine and feline oral cavity tumours and tumour-like lesions: a retrospective study of 486 cases (2015-2017). J Comp Pathol 2019; 172: 80-7.
  • Munday JS, Löhr CV, Kiupel M. Tumors of the ali-mentary tract. Meuten DJ. ed. In: Tumors in Do-mestic Animals. Iowa: John Wiley & Sons, Inc. Ames, 2017; pp.500-43.
  • Niemiec BA. Oral pathologies. Top Companion Anim Med 2008; 23(2): 59-71.
  • Poulet FM, Valentine BA, Summers BA. A survey of epithelial odontogenic tumors and cysts in dogs and cats. Vet Pathol 1992; 29(5): 369-80.
  • Putnová B, Burová J, Georgiou M, Fichtel T, Stehlík L, Frgelecová L, Škorič M. Occurrence site of canine oral lesions: a retrospective study of 659 cases. Acta Vet Brno 2020; 89(2): 179-87.
  • Ramos-Vara JA, Beissenherz ME, Miller MA, John-son GC, Pace LW, Fard A, Kottler SJ. Retrospec-tive study of 338 canine oral melanomas with clinical, histologic, and immunohistochemical re-view of 129 cases. Vet Pathol 2000; 37(6): 597-608.
  • Sundberg JP, Smith EK, Herron AJ, Jenson AB, Burk RD, Van Ranst M. Involvement of canine oral papillomavirus in generalized oral and cutaneous verrucosis in a Chinese Shar Pei dog. Vet Pathol 1994; 31(2): 183-7.
  • Svendenius L, Warfvinge G. Oral pathology in Swe-dish dogs: A retrospective study of 280 biopsies. J Vet Dent 2010; 27(2): 91-7.
  • Uzal FA, Plattner BL, Hostetter JM. Alimentary sys-tem. Maxie M. ed. In: Jubb, Kennedy, and Palm-ers` Pathology of Domestic Animals. Missouri: Elsevier, 2016; pp. 2-28.
  • Verhaert L. Oral proliferative lesions in the dog and cat. Eur J Companion Anim Pract 2010; 20(3): 1-3.
  • Vos JH, Van der GaagI. Canine and feline oral‐pharyngeal tumours. J Vet MedA 1987; 34(1-10): 420-7.
  • Vural SA, Keleş H, Özsoy ŞY, Özkul IA. Köpek ve kedilerde 1977-2005 yılları arasında saptanan orofaringeal bölge tümörleri: Retrospektif çalışma. Ankara Univ Vet Fak Derg2007; 54(3): 197-203.
  • Wingo K. Histopathologic diagnoses from biopsies of the oral cavity in 403 dogs and 73 cats. J Vent Dent 2018; 35(1): 7-17.
  • Yoshida K, Yanai T, Iwasaki T, Sakai H, Ohta J, Kati S, Mikami T, Lackner AA, Masegi T. Clinicopatho-logical study of canine oral epulides. J Vet Sci 1999; 61(8): 897-902.

Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs

Yıl 2022, Cilt: 19 Sayı: 2, 129 - 135, 01.08.2022
https://doi.org/10.32707/ercivet.1142611

Öz

Oral neoplasms and non-neoplastic lesions are commonly encountered pathologies in dogs. The histopatho-logical examination of these lesions is required to make a diagnosis and lead the practitioners to appropriate treatment. This study aims to retrospectively document pathological lesions commonly observed in the oral cavity of dogs. In this context, 167 oral pathology cases were investigated in dogs of different breeds, genders, and age groups in the years between 2010 and 2020. Oral pathologies were classified as neoplastic (benign and malignant neoplasms) and non-neoplastic lesions according to the histopathological features diagnosed by the hematoxylin and eosin staining method. The results showed that malign (46.10%; 77/167) and benign neoplasms (40.11%; 67/167) were predominant, but non-neoplastic lesions (13.77%; 23/167) were restricted. The most common malignant neoplasm was malignant melanoma (50.64%; 39/77), while odontogenic neoplasms were determined as the most common benign neoplasms (74.62%; 50/67). When the affected patient profiles were evaluated, the results showed that males were more prone to oral pa-thologies (M/F: 62.87%/35.32%; 105/59), mostly affected life stage was senior (79.48%; 31/39), and large pure breed dogs were the most commonly encountered dog breeds (49.10%; 82/167), followed by mixed breeds (19.76%; 33/167). These findings showed statistically significant differences by the chi-square test. In addition, the most common affected area in the oral cavity was found to be the gingiva (30.76%; 12/39). As a result, this study contributes to the knowledge about the most common oral pathologies in terms of gender, age, breed, and affected area.

Kaynakça

  • Bergman PJ.Canine oral melanoma. Clin Tech Small Anim Pract 2007; 22(2): 55-60.
  • Bonfanti U,Bertazzolo W,Gracis M,Roccabianca P, Romanelli G, Palermo G, Zini E. Diagnostic value of cytological analysis of tumours and tumour-like lesions of the oral cavity in dogs and cats: A pro-spective study on 114 cases. Vet J 2015; 205(2): 322-7.
  • Brønden LB, Eriksen T, Kristensen AT. Oral malig-nant melanomas and other head and neck neo-plasms in Danish dogs-data from the Danish Vet-erinary Cancer Registry. Acta Vet Scand 2009; 51(1): 1-6.
  • Cray M, Selmic LE, Ruple A. Demographics of dogs and cats with oral tumors presenting to teaching hospitals: 1996-2017. J Vet Sci 2020; 21: 5.
  • Creevy KE, Grady J, Little SE, Little SE, Moore GE, Strickler BG, Thompson S, Webb JA. 2019 AAHA canine life stage guidelines. J Am Anim Hosp Assoc 2019; 55(6): 267-90.
  • Fiani N, Verstraete FJ, Kass PH, Cox DP. Clinico-pathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995-2005). J Am Vet Med Assoc 2011; 238(4): 495-500.
  • Fulton A, Arzi B, Murphy B, Naydan DK, Verstraete FJ. The expression of calretinin and cytokeratins in canine acanthomatous ameloblastoma and oral squamous cell carcinoma. Vet Comp Oncol 2014; 12(4): 258-65.
  • Goldschmidt MH. Benign and malignant melanocytic neoplasms of domestic animals. Am J Dermato-pathol 1985;7: 203-12.
  • Head KW, Cullen JM, Dubielzig RR, Else WR, Mis-drop W, Patnaik AK, Tateyama S, Van der Gaag I. Histological classification of tumors of the alimentary system in domestic animals. In: WHO International Histological Classification of Tumors of Domestic Animals Armed Forces Institute of Pathology, American Registry of Pathology. Second Edition. Washington: World Health Organization, 2003; pp. 29-57.
  • Lange CE, Favrot C. Canine papillomaviruses. Vet Clin Small Anim 2011; 41(6): 1183-95.
  • Liptak JM, Withrow SJ. Oral tumours. Withrow SJ. Vail DM. eds. In: Withrow &Mac Ewen’s Small Animal Clinical Oncology. Philadelphia: Elsevier Saunders, 2013; pp. 381-98.
  • Lommer MJ. Oral inflammation in small animals. Vet Clin Small Anim 2013; 43(3): 555-71.
  • Mikiewicz M, Paździor-Czapula K, Gesek M, Lemi-shevskyi V, Otrocka-Domagała I. Canine and feline oral cavity tumours and tumour-like lesions: a retrospective study of 486 cases (2015-2017). J Comp Pathol 2019; 172: 80-7.
  • Munday JS, Löhr CV, Kiupel M. Tumors of the ali-mentary tract. Meuten DJ. ed. In: Tumors in Do-mestic Animals. Iowa: John Wiley & Sons, Inc. Ames, 2017; pp.500-43.
  • Niemiec BA. Oral pathologies. Top Companion Anim Med 2008; 23(2): 59-71.
  • Poulet FM, Valentine BA, Summers BA. A survey of epithelial odontogenic tumors and cysts in dogs and cats. Vet Pathol 1992; 29(5): 369-80.
  • Putnová B, Burová J, Georgiou M, Fichtel T, Stehlík L, Frgelecová L, Škorič M. Occurrence site of canine oral lesions: a retrospective study of 659 cases. Acta Vet Brno 2020; 89(2): 179-87.
  • Ramos-Vara JA, Beissenherz ME, Miller MA, John-son GC, Pace LW, Fard A, Kottler SJ. Retrospec-tive study of 338 canine oral melanomas with clinical, histologic, and immunohistochemical re-view of 129 cases. Vet Pathol 2000; 37(6): 597-608.
  • Sundberg JP, Smith EK, Herron AJ, Jenson AB, Burk RD, Van Ranst M. Involvement of canine oral papillomavirus in generalized oral and cutaneous verrucosis in a Chinese Shar Pei dog. Vet Pathol 1994; 31(2): 183-7.
  • Svendenius L, Warfvinge G. Oral pathology in Swe-dish dogs: A retrospective study of 280 biopsies. J Vet Dent 2010; 27(2): 91-7.
  • Uzal FA, Plattner BL, Hostetter JM. Alimentary sys-tem. Maxie M. ed. In: Jubb, Kennedy, and Palm-ers` Pathology of Domestic Animals. Missouri: Elsevier, 2016; pp. 2-28.
  • Verhaert L. Oral proliferative lesions in the dog and cat. Eur J Companion Anim Pract 2010; 20(3): 1-3.
  • Vos JH, Van der GaagI. Canine and feline oral‐pharyngeal tumours. J Vet MedA 1987; 34(1-10): 420-7.
  • Vural SA, Keleş H, Özsoy ŞY, Özkul IA. Köpek ve kedilerde 1977-2005 yılları arasında saptanan orofaringeal bölge tümörleri: Retrospektif çalışma. Ankara Univ Vet Fak Derg2007; 54(3): 197-203.
  • Wingo K. Histopathologic diagnoses from biopsies of the oral cavity in 403 dogs and 73 cats. J Vent Dent 2018; 35(1): 7-17.
  • Yoshida K, Yanai T, Iwasaki T, Sakai H, Ohta J, Kati S, Mikami T, Lackner AA, Masegi T. Clinicopatho-logical study of canine oral epulides. J Vet Sci 1999; 61(8): 897-902.
Toplam 26 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Hazal Ozturk-gurgen Bu kişi benim 0000-0003-2748-6189

Pembe Dilara Kecıcı Bu kişi benim 0000-0003-1151-179X

Kivilcim Sonmez Bu kişi benim 0000-0001-8256-9943

Aydin Gurel Bu kişi benim 0000-0002-0266-8771

Yayımlanma Tarihi 1 Ağustos 2022
Gönderilme Tarihi 16 Ekim 2021
Kabul Tarihi 4 Nisan 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 19 Sayı: 2

Kaynak Göster

APA Ozturk-gurgen, H., Kecıcı, P. D., Sonmez, K., Gurel, A. (2022). Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, 19(2), 129-135. https://doi.org/10.32707/ercivet.1142611
AMA Ozturk-gurgen H, Kecıcı PD, Sonmez K, Gurel A. Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs. Erciyes Üniv Vet Fak Derg. Ağustos 2022;19(2):129-135. doi:10.32707/ercivet.1142611
Chicago Ozturk-gurgen, Hazal, Pembe Dilara Kecıcı, Kivilcim Sonmez, ve Aydin Gurel. “Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 19, sy. 2 (Ağustos 2022): 129-35. https://doi.org/10.32707/ercivet.1142611.
EndNote Ozturk-gurgen H, Kecıcı PD, Sonmez K, Gurel A (01 Ağustos 2022) Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 19 2 129–135.
IEEE H. Ozturk-gurgen, P. D. Kecıcı, K. Sonmez, ve A. Gurel, “Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs”, Erciyes Üniv Vet Fak Derg, c. 19, sy. 2, ss. 129–135, 2022, doi: 10.32707/ercivet.1142611.
ISNAD Ozturk-gurgen, Hazal vd. “Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi 19/2 (Ağustos 2022), 129-135. https://doi.org/10.32707/ercivet.1142611.
JAMA Ozturk-gurgen H, Kecıcı PD, Sonmez K, Gurel A. Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs. Erciyes Üniv Vet Fak Derg. 2022;19:129–135.
MLA Ozturk-gurgen, Hazal vd. “Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs”. Erciyes Üniversitesi Veteriner Fakültesi Dergisi, c. 19, sy. 2, 2022, ss. 129-35, doi:10.32707/ercivet.1142611.
Vancouver Ozturk-gurgen H, Kecıcı PD, Sonmez K, Gurel A. Retrospective Evaluation of Pathological Lesions of the Oral Cavity in Dogs. Erciyes Üniv Vet Fak Derg. 2022;19(2):129-35.