Optimizing and Modeling of Microwave Assisted Extraction of Phenolics from Dandelion (Taraxacum officinale) by Response Surface Methodology

Yıl 2022, Cilt: 38 Sayı: 1, 128 - 136, 30.04.2022

Nilay Beğiç

Öz

Abstract: Modelling microwave assisted extraction (MAE) of phenolics from dandelion (Taraxacum officinale) was carried out via response surface methodology in this study. Face-centered composite design was used to optimize the MAE factors as temperature of extraction, time of extraction, concentration of solvent and ratio between solid and solvent. Process factors of the MAE were optimized for maximum total phenolic content (TPC) of the dandelion extract. When the relationship between independent parameters and response was examined, the model calculated for TPC was found to be significant (p<0.0001). It was determined that the most significant factor is extraction temperature for the extraction of phenolics from the dandelion by MAE. The most insignificant parameter was determined as solid-to-solvent ratio parameter in MAE. Experimentally found and predicted data were found to be compatible with each other. It shows success of both the model and the optimization. The TPC yield was obtained as 1.26 mmol TR/g-dried sample in optimum MAE conditions. Consequently, the modeled method can be used for the extraction of phenolics from the dandelion in the pharmaceutical and food industries.

Anahtar Kelimeler

Microwave-Assisted Extraction, Dandelion, Total Phenolic Content, Response Surface Methodology

Teşekkür

The author thanks Istanbul University-Cerrahpaşa, Department of Analytical Chemistry for sharing their research infrastructures.

Yanıt Yüzey Metodolojisi ile Karahindiba'dan (Taraxacum officinale) Fenoliklerin Mikrodalga Destekli Ekstraksiyonunun Optimizasyonu ve Modellenmesi

Öz

Bu çalışmada, karahindibadan (Taraxacum officinale) fenoliklerin mikrodalga destekli ekstraksiyonunun (MAE) modellenmesi, yanıt yüzey metodolojisi ile gerçekleştirilmiştir. Ekstraksiyon sıcaklığı, ekstraksiyon süresi, çözücü konsantrasyonu ve katı ile çözücü arasındaki oran gibi MAE faktörlerini optimize etmek için yüz merkezli kompozit tasarım kullanıldı. MAE'nin işlem faktörleri, karahindiba ekstraktının maksimum toplam fenolik içeriği (TPC) için optimize edildi. Bağımsız parametreler ile yanıt arasındaki ilişki incelendiğinde TPC için hesaplanan model anlamlı bulundu (p<0,0001). MAE ile karahindibadan fenoliklerin ekstraksiyonunda en önemli faktörün ekstraksiyon sıcaklığı olduğu belirlenmiştir. MAE'de en önemsiz parametre katı-çözücü oranı parametresi olarak belirlendi. Deneysel olarak bulunan ve tahmin edilen verilerin birbiriyle uyumlu olduğu görülmüştür. Bu sonuç, hem modelin hem de optimizasyonun başarısını gösterir. TPC verimi, optimum MAE koşullarında 1.26 mmol TR/g kurutulmuş numune olarak elde edildi. Sonuç olarak, modellenen yöntem, farmasötik ve gıda endüstrilerinde karahindibadan fenoliklerin ekstraksiyonu için kullanılabilir bir yöntemdir.

Anahtar Kelimeler

Mikrodalga-Destekli Ekstraksiyon, Karahindiba, Toplam Fenolik İçerik, Yanıt Yüzey Metodolojisi

Kaynakça

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