Böbrek Taşlarının Yapısı, Çeşitli Asitlerin Etkisi ve Tedavi Yöntemleri

Yıl 2021, , 761 - 775, 31.08.2021

Emine Aytar , Hacer Önal , Şerife Yalçın

https://doi.org/10.18185/erzifbed.910641

Öz

Böbrek taşı, insanların çok çektiği ve çok sık karşılaştığı hastalıklardan biridir. Tedavisi genellikle hastanın ve taşın özelliğine göre konservatif, medikal veya cerrahi olarak yapılır. Bu çalışmada üriner sistem taş hastalıklarından kalsiyum oksalat böbrek taşının yapısı incelenmiş ve günümüzde bu taşın tedavisinde kullanılan yöntemler, tedavideki başarısı, bu yöntemlerin avantaj ve dezavantajları karşılaştırılarak asit etkisi araştırılmıştır. İlk olarak kalsiyum oksalat yapısı sentezlenerek asetik asit, asetik asit glacial, sitrik asit, limon ve hidroklorik asidin bu yapıya etkisi araştırıldı. Ardından XRD, FT-IR ve SEM yöntemleriyle taşın yapısı belirlendi. CaC2O4 taşı sentezlendi ve spektroskopik yöntemlerle incelendi. Tüm sentezlerin X ışını kırınım modeli benzer bir yapıya ve bir kalsiyum oksalat tepesine sahip olduğu tespit edildi. Literatür ile uyumludur. FT-IR spektrumunda, incelenen tüm sentezler için 3700 ile 2760 cm-1 arasındaki bölgede geniş bir spektrum gözlemlendi. H6 için COM yapısını ve H1, H2, H3 ve H4 için COD yapısını ortaya koyduğu görüldü. Diğer asitlerin sentetik kalsiyum oksalat üzerindeki etkileri SEM görüntüleri kullanılarak karşılaştırıldı. Partiküllerin boyutsal dağılımının üniform ve sitrik asit ilave edilen H4 için diğerlerinden daha küçük olduğu durumlarda elde edildi. Glacial asetik asit eklenerek gerçekleşen sentezde partiküllerde kümelenme eğiliminin diğerlerine göre daha yüksek olduğu görüldü.

Anahtar Kelimeler

Böbrek Taşı,, Kalsiyum Oksalat,, Asit,, XRD,, FTIR.

The Structure, The Effect of Variety Acids and Treatment Methods of Kidney Stones

Öz

A kidney stone is one of the diseases that people have a lot of suffered and faced very often. Its treatment is generally performed conservatively, medically, or surgically according to the characteristics of the patient and the stone. In this study, the structure of calcium oxalate kidney stone from urinary system stone diseases is examined and the methods used in the treatment of this stone today, the success in the treatment, the advantages and disadvantages of these methods were compared and researched acid effect on the structure of these stone. The calcium oxalate structure was synthesized in this study. The effect of acetic acid, acetic acid glacial, citric acid, lemon and hydrochloric acid on this structure was investigated. Then, the structure of stone was determined by XRD, FT-IR and SEM methods. The CaC2O4 stone was synthesized and examined using spectroscopic methods. The X-ray diffraction pattern of all syntheses has a similar structure and has a calcium oxalate peak. It is compatible with the literature. In the FT-IR spectrum, a broad spectrum peak was observed in the region between 3700 and 2760 cm-1 for all studied syntheses. It reveals the COM structure for H6, and the COD structure for H1, H2, H3, and H4. The effects of other acids on synthetic calcium oxalate were compared by using SEM images. It was obtained where the dimensional distribution of the particles was uniform and smaller than the others for the H4 which citric acid was added. It was observed that the tendency to cluster in the particles was higher than the others in the synthesis by adding glacial acetic acid.

Anahtar Kelimeler

Kidney Stone,, Calcium Oxalate,, Acids,, XRD,, FTIR.

Kaynakça

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