Investigation of SiO2 Nanoparticles Induced Toxicity in Larvae of Fruit Flies

Yıl 2018, Cilt: 11 Sayı: 2, 255 - 262, 31.08.2018

Çağla Ersöz Deniz Altun Çolak

https://doi.org/10.18185/erzifbed.412920

Cited By: 1

Öz

Silicon dioxide (SiO₂)
nanoparticles (NPs) are widely used in many important areas of our lives such
as agriculture, textile, electronics, cosmetics, paint industry, and medicine.
NPs cause toxic effects in various tissues and organs of the body by entering
different ways. The aim of this study is to evaluate the possible toxic effects
of SiO₂ NP (20- 55 nm), among the commonly used NPs, on 3^rd
instar larvae of Drosophila melanogaster.
For this purpose, controlled experiments were carried out to fruit fly larvae
at different time intervals by exposed at 0.1, 1, 5 and 10 mg/mL concentrations
SiO₂ NP. Statistical analysis of the values of the control and
treatment groups was performed with SPSS (version 15.0). According to the
results obtained in the study, when all concentrations compared to the control
it was determined that SiO₂ NPs applied to the larvae increased the
mortality and decreased the recovery of pupae and emergence of adults.

Anahtar Kelimeler

Drosophila melanogaster, SiO2 NP, Toxicity, Larval mortality, Lifespan rate

Meyve Sineği Larvalarında SiO2 Nanopartikülünün Toksisite Değerlendirmesi

Öz

Silisyum dioksit (SiO₂)
nanopartiküllerinin (NP’lerinin) tarım, tekstil, elektronik, kozmetik, boya
endüstrisi ve tıp gibi hayatımızın pek çok önemli alanında yaygın olarak
kullanıldığı bilinmektedir. NP’ler vücuda farklı yollardan girerek değişik doku
ve organlarda toksik etkiye neden olmaktadır. Bu çalışmanın amacı, sık
kullanılan NP’ler arasında yer alan SiO₂ NP’nin (20- 55 nm) Drosophila melanogaster'in 3. evre
larvaları üzerine olası toksik etkileri değerlendirilmiştir. Bu amaçla, meyve
sineği larvalarına 0.1, 1, 5 ve 10 mg/mL konsantrasyonlarda SiO₂
NP’leri uygulanarak farklı saat aralıklarında kontrollü deneyler yapılmıştır.
Kontrol ve uygulama gruplarına ait değerlerin istatistiksel analizi SPSS
(version 15.0) ile yapılmıştır. Çalışma sonucunda elde edilen verilere göre,
larvalara uygulanan SiO₂ NP’lerinin mortaliteyi tüm
konsantrasyonlarda kontrole göre arttırdığı, pupa ve ergin birey oluşumunu ise
azalttığı belirlenmiştir.

Anahtar Kelimeler

Drosophila melanogaster, SiO2 NP, Toksisite, Larval mortalite, Yaşama oranı

Kaynakça

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