Araştırma Makalesi
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Evaluation of Hematological Parameters in Differentiating Central and Peripheral Vertigo in Patients with Vertigo

Yıl 2023, Cilt: 16 Sayı: 3, 608 - 614, 31.12.2023
https://doi.org/10.18185/erzifbed.1029791

Öz

Abstract
Central and peripheral causes play a role in the etiology of patients who apply to the emergency department with the complaint of vertigo. In our study, in the differential diagnosis of patients with central and peripheral vertigo, the usability of hematological parameters (white blood cell (WBC), leukocyte, neutrophil, lymphocyte, monocytes, basophil, eosinophil and platelet counts, red cell distribution width (RDW), platelet distribution width (PDW)) and platelet/lymphocyte (PLR), neutrophil/lymphocyte (NLR) ratios was investigated. This is a retrospective study including 215 patients, 179 (83.3%)with peripheral vertigo and 36 (16.7%) with central vertigo. Patients who were discharged from the emergency department with the complaint of vertigo or were admitted to the otolaryngology clinic were considered as peripheral vertigo, and patients who had findings on central imaging or were hospitalized in neurology/neurosurgery clinics were considered as central vertigo. There was a statistically significant difference between the groups in terms of age and gender of patients with peripheral and central vertigo (p<0.05). There was no statistically significant difference between the groups in terms of hematological parameters (p>0.05). We found that the values we looked at were not useful in the differential diagnosis.

Öz
Acil servise vertigo şikayetiyle başvuran hastaların etiyolojisinde santral ve periferik sebepler rol oynamaktadır. Çalışmamızda santral ve periferik vertigolu hastaların ayırıcı tanısında hematolojik parametrelerin(beyaz küre, lökosit, nötrofil, lenfosit, monosit, bazofil, eozinofil ve trombosit sayıları, kırmızı küre dağılım genişliği (RDW), platelet dağılım genişliği (PDW)), ve platelet/lenfosit, nötrofil/lenfosit oranlarının kullanılabilirliği araştırıldı. Bu çalışma 179’u (%83.3) periferik vertigo, 36’sı (%16.7) santal vertigo olan toplam 215 hastanın dahil edildiği retrospektif bir çalışmadır. Acil servise vertigo şikayetiyle başvurup taburcu edilen ya da kulak burun boğaz kliniğine yatırılan hastalar periferik vertigo olarak, santral görüntülemelerde bulgusu olan ya da nöroloji/nöroşirurji kliniklerine yatırılan hastalar santral vertigo olarak kabul edildi. Periferik ve santral vertigolu hastaların yaş ve cinsiyet durumları bakımından gruplar arasında istatistiksel olarak anlamlı fark saptandı(p<0.05). Gruplar arasında hematolojik parametreler bakımından istatistiksel olarak anlamlı bir fark yoktu(p>0.05). Baktığımız değerlerin ayırıcı tanıda faydalı olmadığını saptadık.

Kaynakça

  • Neuhauser, H.K., Radtke, A., von Brevern, M., Lezius, F., Feldmann, M., Lempert, T. 2008. “Burden of Dizziness and Vertigo in the Community”, Arch Intern Medicine, 168(19):2118–2124.
  • Kroenke, K., Lucas, C.A., Rosenberg, ML., et al. 1992. “Causes of persistent dizziness. A prospective study of 100 patients in ambulatory care”, Ann Intern Medicine, 117:898.
  • Sloane, P.D., Dallara, J., Roach, C., et al. 1994. “Management of dizziness in primary care”, J Am Board Fam Pract, 7:1.
  • Herr, R.D., Zun, L., Mathews, JJ. 1989. “A directed approach to the dizzy patient”, Ann Emerg Medicine, 18:664.
  • Skiendzielewski, J.J., Martyak, G. 1980. “The weak and dizzy patient”, Ann Emerg Medicine, 9:353.
  • Newman-Toker, D.E., Hsieh, Y.H., Camargo, C.A Jr., et al. 2008. “Spectrum of dizziness visits to US emergency departments: cross-sectional analysis from a nationally representative sample”, Mayo Clin Proc, 83:765.
  • Chawla, N., Olshaker, JS. 2006. “Diagnosis and management of dizziness and vertigo”, Med Clin North Am, 90(2):291-304.
  • Olshaker, J.S. 2009. “Dizziness and vertigo”, In: Marx, J.A., Hockberger, R.S., Walls, R.M., Adams, J.G., Barsan, W.G., Biros, M.H., Danzl, D.F., Gausche-Hill, M., Ling, L.J., Newton, E.J., editors. Rosen’s Emergency Medicine. 7th ed. Philadelphia: Mosby Elsevier,;93-100.
  • Gönüllü, H. 2008. “Acil serviste vertigonun ayırıcı tanısı”, Master thesis, Ondokuz Mayıs University Department of Emergency Medicine, Samsun.
  • Jilma, B., Blann, A., Pernerstorfer, T., et al. 1999. “Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin”, Am J Respir Crit Care Medicine, 159:857-63.
  • Dionigi, R., Dominioni, L., Benevento, A., et al. 1994. “Effects of surgical trauma of laparoscopic vs. open cholecystectomy” Hepatogastroenterology, 41:471-76.
  • O‘Mahony, J.B., Palder, S.B., Wood, J.J., et al. 1984. “Depression of cellular immunity after multiple trauma in the absence of sepsis”, J Trauma, 24:869- 75.
  • Zahorec, R. 2001. “Ratio of neutrophil to lymphocyte counts—Rapid and simple parameter of systemic inflammation and stress in critically ill”, Bratisl Lek Listy, 102:5-14.
  • Imtiaz, F., Shafique, K., Mirza, S.S., Ayoob, Z., Vart, P., Rao, S. 2012. “Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population”, Int Arch Medicine, 5(1):2.
  • Folsom, A.R., Wu, K.K., Rosamond, W.D., Sharrett A.R, Chambless, L.E. 1997. “Prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study”, Circulation, 96:1102–1108.
  • Kocaman, S.A., Sahinarslan, A., Kunak, T., et al. 2011. “The particular interactions of the traditional cardiovascular risk factors with different circulating specific 69 leukocyte subtype counts in blood: an observational study”, Anadolu Kardiyol Dergisi, 11(7):573–581.
  • Ducloux, D., Challier, B., et al. 2003. “CD4 cell lymphopenia and atherosclerosis in renal transplant recipients”, J Am Soc Nephrol, 14;767–772.
  • Hotchkiss, R.S., Karl, I.E. 2003. “The pathophysiology and treatment of sepsis” N Engl J Medicine, 348: 138–150.
  • Ntaisos, G., Gürer, Ö., Faouzi, M., Aubert, C., Michel, P. 2011. “Red cell distribution width does not predict stroke severity or functional outcome”, International Journal of Stroke World Stroke Organization 2012; 7: 2–6
  • Ani, C., Ovbiagele, B. 2009. “Elevated red blood cell distribution width predicts mortality in persons with known stroke”, J Neurol Sci, 277:103–8
  • Güldiken, B., Özkan, H., Kabayel, L. 2008. “Akut İskemik İnmede Ortalama Trombosit Hacmi ve Periferik Kan Hücre Sayısı Yanıtı”, Trakya Univ Tip Fak Dergisi, 25(2):130-5
  • O’Malley, T., Langhorne, P., Elton, R.A., Stewart, C. 1995. “Platelet size in stroke patients”, Stroke, 26:995-9 Karatas, M. 2008. “Central vertigo and dizziness: epidemiology, differential diagnosis, andcommon causes”, Neurologist, Nov;14(6):355-64.
Yıl 2023, Cilt: 16 Sayı: 3, 608 - 614, 31.12.2023
https://doi.org/10.18185/erzifbed.1029791

Öz

Kaynakça

  • Neuhauser, H.K., Radtke, A., von Brevern, M., Lezius, F., Feldmann, M., Lempert, T. 2008. “Burden of Dizziness and Vertigo in the Community”, Arch Intern Medicine, 168(19):2118–2124.
  • Kroenke, K., Lucas, C.A., Rosenberg, ML., et al. 1992. “Causes of persistent dizziness. A prospective study of 100 patients in ambulatory care”, Ann Intern Medicine, 117:898.
  • Sloane, P.D., Dallara, J., Roach, C., et al. 1994. “Management of dizziness in primary care”, J Am Board Fam Pract, 7:1.
  • Herr, R.D., Zun, L., Mathews, JJ. 1989. “A directed approach to the dizzy patient”, Ann Emerg Medicine, 18:664.
  • Skiendzielewski, J.J., Martyak, G. 1980. “The weak and dizzy patient”, Ann Emerg Medicine, 9:353.
  • Newman-Toker, D.E., Hsieh, Y.H., Camargo, C.A Jr., et al. 2008. “Spectrum of dizziness visits to US emergency departments: cross-sectional analysis from a nationally representative sample”, Mayo Clin Proc, 83:765.
  • Chawla, N., Olshaker, JS. 2006. “Diagnosis and management of dizziness and vertigo”, Med Clin North Am, 90(2):291-304.
  • Olshaker, J.S. 2009. “Dizziness and vertigo”, In: Marx, J.A., Hockberger, R.S., Walls, R.M., Adams, J.G., Barsan, W.G., Biros, M.H., Danzl, D.F., Gausche-Hill, M., Ling, L.J., Newton, E.J., editors. Rosen’s Emergency Medicine. 7th ed. Philadelphia: Mosby Elsevier,;93-100.
  • Gönüllü, H. 2008. “Acil serviste vertigonun ayırıcı tanısı”, Master thesis, Ondokuz Mayıs University Department of Emergency Medicine, Samsun.
  • Jilma, B., Blann, A., Pernerstorfer, T., et al. 1999. “Regulation of adhesion molecules during human endotoxemia. No acute effects of aspirin”, Am J Respir Crit Care Medicine, 159:857-63.
  • Dionigi, R., Dominioni, L., Benevento, A., et al. 1994. “Effects of surgical trauma of laparoscopic vs. open cholecystectomy” Hepatogastroenterology, 41:471-76.
  • O‘Mahony, J.B., Palder, S.B., Wood, J.J., et al. 1984. “Depression of cellular immunity after multiple trauma in the absence of sepsis”, J Trauma, 24:869- 75.
  • Zahorec, R. 2001. “Ratio of neutrophil to lymphocyte counts—Rapid and simple parameter of systemic inflammation and stress in critically ill”, Bratisl Lek Listy, 102:5-14.
  • Imtiaz, F., Shafique, K., Mirza, S.S., Ayoob, Z., Vart, P., Rao, S. 2012. “Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population”, Int Arch Medicine, 5(1):2.
  • Folsom, A.R., Wu, K.K., Rosamond, W.D., Sharrett A.R, Chambless, L.E. 1997. “Prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study”, Circulation, 96:1102–1108.
  • Kocaman, S.A., Sahinarslan, A., Kunak, T., et al. 2011. “The particular interactions of the traditional cardiovascular risk factors with different circulating specific 69 leukocyte subtype counts in blood: an observational study”, Anadolu Kardiyol Dergisi, 11(7):573–581.
  • Ducloux, D., Challier, B., et al. 2003. “CD4 cell lymphopenia and atherosclerosis in renal transplant recipients”, J Am Soc Nephrol, 14;767–772.
  • Hotchkiss, R.S., Karl, I.E. 2003. “The pathophysiology and treatment of sepsis” N Engl J Medicine, 348: 138–150.
  • Ntaisos, G., Gürer, Ö., Faouzi, M., Aubert, C., Michel, P. 2011. “Red cell distribution width does not predict stroke severity or functional outcome”, International Journal of Stroke World Stroke Organization 2012; 7: 2–6
  • Ani, C., Ovbiagele, B. 2009. “Elevated red blood cell distribution width predicts mortality in persons with known stroke”, J Neurol Sci, 277:103–8
  • Güldiken, B., Özkan, H., Kabayel, L. 2008. “Akut İskemik İnmede Ortalama Trombosit Hacmi ve Periferik Kan Hücre Sayısı Yanıtı”, Trakya Univ Tip Fak Dergisi, 25(2):130-5
  • O’Malley, T., Langhorne, P., Elton, R.A., Stewart, C. 1995. “Platelet size in stroke patients”, Stroke, 26:995-9 Karatas, M. 2008. “Central vertigo and dizziness: epidemiology, differential diagnosis, andcommon causes”, Neurologist, Nov;14(6):355-64.
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Mühendislik
Bölüm Makaleler
Yazarlar

Orhan Tanrıverdi 0000-0002-4677-0946

Zeynep Çakır 0000-0002-5490-1192

Erken Görünüm Tarihi 25 Aralık 2023
Yayımlanma Tarihi 31 Aralık 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 16 Sayı: 3

Kaynak Göster

APA Tanrıverdi, O., & Çakır, Z. (2023). Evaluation of Hematological Parameters in Differentiating Central and Peripheral Vertigo in Patients with Vertigo. Erzincan University Journal of Science and Technology, 16(3), 608-614. https://doi.org/10.18185/erzifbed.1029791