EPIDEMIOLOGY of COMMON SKIN CANCERS

Yıl 2019, Cilt: 4 - Dermatoloji ve Halk Sağlığı Özel Sayısı, 52 - 60, 11.03.2019

Ersoy Acer Hilal Kaya Erdoğan

https://doi.org/10.35232/estudamhsd.499257

Öz

Non-melanoma skin cancers are the most common
cancers in people with fair skin and basal cell carcinoma (BCC) is the most
common among them. BCC progresses slowly, is locally aggressive and rarely
metastasizes. Although the mortality rate is low, morbidity and disease cost
burden is high. Cutaneous squamous cell carcinoma (SCC) is the second most
common skin cancer. Most of cutaneous SCCs are treated, but may cause
recurrence, metastasis and mortaliy. Melanoma is rare compared to BCC and SCC
but it is a very important public health problem due to its high mortality.
Melanoma is the most aggressive and has the highest mortality rate in all skin
cancers and early diagnosis is vital. Various environmental, phenotypic and
genotypic factors, particularly ultraviolet (UV) are involved in the etiology
of these three skin cancers. The incidence of these three skin cancer is increasing
rapidly worldwide. People should be educated about skin cancers and protection
from factors, particularly UV that are associated with etiology of skin
cancers. Thus, morbidity, mortality and cost burden associated with skin
cancers will decrease.

Anahtar Kelimeler

Basal cell carcinoma, epidemiology, melanoma, squamous cell carcinoma

SIK GÖRÜLEN DERİ KANSERLERİNİN EPİDEMİYOLOJİSİ

Öz

Melanom
dışı deri kanserleri beyaz ırkta en sık görülen kanserlerdir ve bunlar arasında
en sık bazal hücreli karsinom (BHK) görülür. BHK yavaş ilerleyen, lokal agresif
ve nadiren metastaz yapan bir deri kanseridir. Mortalitesi düşük olmasına
rağmen morbiditesi ve hastalık maliyet yükü yüksektir. Kutanöz skuamöz hücreli
karsinom (SHK) ise ikinci en sık görülen deri kanseridir. Bu hastaların büyük
bir kısmı tedavi edilir; ancak rekürrens, metastaz ve mortaliteye neden
olabilir. Melanom, BHK ve SHK’ya göre nadirdir ancak yüksek mortalitesi
nedeniyle çok önemli bir halk sağlığı problemidir. Tüm deri kanserleri içinde
melanom en agresif ve mortalitesi en yüksek olanıdır ve erken tanı hayati öneme
sahiptir. Üç deri kanserinin etiyolojisinde de başta ultraviyole (UV) olmak
üzere çeşitli çevresel, fenotipik ve genotipik faktörler rol oynamaktadır. Bu
üç deri kanserinin insidansı dünya çapında hızla artmaktadır. İnsanlar deri
kanserleri ve deri kanserleri ile ilişkili başta UV olmak üzere etiyolojide
rolü olan faktörlerden korunma konusunda eğitilmelidir. Böylece deri kanserleri
ile ilişkili morbidite, mortalite ve maliyet yükü azalacaktır

Anahtar Kelimeler

Bazal hücreli karsinom, epidemiyoloji, melanom, skuamöz hücreli karsinom

Kaynakça

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