Araştırma Makalesi
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ASSOCIATION OF VITAMIN D LEVEL WITH AGE, GENDER, LIVING PLACE AND SEASON OF THE YEAR IN CHILDREN AND ADOLESCENTS

Yıl 2020, , 114 - 118, 25.09.2020
https://doi.org/10.34108/eujhs.772031

Öz

The aim of the present study was to evaluate the association of 25(OH)D vitamin level with season of the year, age, gender and living place in children and adolescents of 0-17 years of age. Children and adolescents who were screened retrospectively from the hospital automation system between September 2016 and September 2017 were evaluated according to region, age, gender and 25 (OH) vitamin D levels. Average age of 5.356 individuals was 8.21±5.48, average 25(OH)D vitamin level was 20.54±13.04 ng/ml. Only 19.7% of all participants (n= 1056) had sufficient level of vitamin D. 25(OH)D vitamin levels of people living in urban and rural areas were similar (p=0.673). Girls had significantly lower 25(OH)D vitamin levels compared to boys (18.5±13.07 and 23.03±12.58 ng/ml, respectively, p<0.001). In terms of age groups, the highest 25(OH)D vitamin levels were observed in 1-6 years of age group (26.97±14.34 ng/ml) while 7-17 years of age group had the lowest level (15.77±9.19 ng/ml) (p<0.001). The highest 25(OH)D vitamin levels were observed in summer season (25.62±14 ng/ml) and the lowest in winter (16.95±11.76 ng/ml) (p<0.001). Vitamin D level was associated with age, gender and season of the years. Health professionals should consider vitamin D deficiency in children and adolescents of 0-17 years of age, a period significant for the development of skeletal system. Vitamin D supplements should be taken in all seasons, and vitamin D deficiency and associated health problems should be eliminated early.

Kaynakça

  • 1. Haimi M, Kremer R. Vitamin D deficiency/insufficiency from childhood to adulthood: Insights from a sunny country. World J Clin Pediatr 2017; 6(1):1-9.
  • 2. Fernández Bustillo JM, Fernández Pombo A, Gómez Bahamonde R, Sanmartín López E, Gualillo O. Vitamin D levels in a pediatric population of a primary care centre: a public health problem? BMC Res Notes 2018; 11(1):801.
  • 3. Manios Y, Moschonis G, Hulshof T, et al. Prevalence of vitamin D deficiency and insufficiency among schoolchildren in Greece: the role of sex, degree of urbanisation and seasonality. Br J Nutr 2017; 118(7):550-558.
  • 4. González-Gross M, Valtueña J, Breidenassel C, et al. Vitamin D status among adolescents in Europe: the Healthy Lifestyle in Europe by Nutrition in Adolescence study. Br J Nutr 2012; 107(5):755-764.
  • 5. Mark KA, Dumas KJ, Bhaumik D, et al. Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1. Cell Rep 2016; 17(5):1227-1237.
  • 6. Braegger C, Campoy C, Colomb V, et al. Vitamin D in the healthy European paediatric population. J Pediatr Gastroenterol Nutr 2013; 56(6):692-701.
  • 7. Doğan N, Aydoğdu Çolak A, Güden N, Üstüner F. Vitamin D deficiency in children aegean region in Turkey. Cumhuriyet Medical Journal 2015; 37:17-22.
  • 8. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357:266–281.
  • 9. Cardoso S, Santos A, Guerra RS, et al. Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional study. BMC Geriatr 2017; 17(1):256.
  • 10. Saki F, Dabbaghmanesh MH, Omrani GR, Bakhshayeshkaram M. Vitamin D deficiency and its associated risk factors in children and adolescents in southern Iran. Public Health Nutr 2017; 20(10):1851-1856.
  • 11. Bucak İH, Almiş H. The Retrospective Analysis of Vitamin D Levels of Pediatric Patients in a Small City Center in Turkey. Sakarya Med J 2016; 6(3):136-140. 12. Karagüzel G, Dilber B, Çan G, ve ark. Seasonal vitamin D status of healthy schoolchildren and predictors of low vitamin D status. J Pediatr Gastroenterol Nutr 2014; 58(5):654-660.
  • 13. Alyahya KO. Vitamin D levels in schoolchildren: a cross-sectional study in Kuwait. BMC Pediatr 2017; 17(1):213.
  • 14. Gilbert-Diamond D, Baylin A, Mora-Plazas M, et al. Vitamin D deficiency and anthropometric indicators of adiposity in school-age children: a prospective study. Am J Clin Nutr 2010; 92(6):1446-1451.
  • 15. Aarskog D, Aksnes L, Markestad T, Rødland O. Effect of estrogen on vitamin D metabolism in tall girls. J Clin Endocrinol Metab 1983; 57(6):1155-1158.
  • 16. Stanczyk FZ, Clarke NJ. Measurement of estradiol--challenges ahead. J Clin Endocrinol Metab 2014; 99(1):56-58.
  • 17. Solak İ, Goksin Cihan F, Mercan S, Kethuda T, Eryılmaz MA. Evaluation of 25-hydroxyvitamin D levels in central Anatolia, Turkey.BioMed Research International 2018; (1):1-5.
  • 18. Sahin ON, Serdar M, Serteser M, Unsal I, Ozpinar A. Vitamin D levels and parathyroid hormone variations of children living in a subtropical climate: a data mining study. Ital J Pediatr 2018; 44(1):40.
  • 19. Andıran N, Çelik N, Akça H, Doğan G. Vitamin D deficiency in children and adolescents. J Clin Res Pediatr Endocrinol 2012; 4(1):25-29.
  • 20. Akman AO, Tumer L, Hasanoglu A, Ilhan M, Caycı B. Frequency of vitamin D insufficiency in healthy children between 1 and 16 years of age in Turkey. Pediatr Int 2011; 53:968–973.
  • 21. Sarma D, Saikia UK, Baro A. Vitamin D Status of School Children in and around Guwahati. Indian J Endocrinol Metab 2019; 23(1):81-85.
  • 22. Erol M, Yiğit Ö, Küçük HS, Bostan Gayret Ö. Vitamin D deficiency in children and adolescents in Bağcılar, İstanbul. J Clin Res Pediatr Endocrinol 2015; 7(2):134-139.
  • 23. Feizabad E, Hossein-Nezhad A, Maghbooli Z, Ramezani M, Hashemian R, Moattari S. Impact of air pollution on vitamin D deficiency and bone health in adolescents. Arch Osteoporos 2017; 12(1):34.

ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ

Yıl 2020, , 114 - 118, 25.09.2020
https://doi.org/10.34108/eujhs.772031

Öz

Çalışmanın amacı 0-17 yaş arası çocuk ve ergenlerde 25(OH)D vitamini seviyesinin mevsim, yaş, cinsiyet ve yerleşim yeri ile ilişkisinin değerlendirilmesidir. Eylül 2016-Eylül 2017 tarihleri arasında hastane otomasyon sisteminden retrospektif olarak taranan çocuklar ve ergenler bölge, yaş, cinsiyet ve 25 (OH) D vitamini düzeyine göre değerlendirildi. Çalışmada yaş ortalaması 8.21±5.48; 25(OH)D vitamini ortalaması 20.54±13.04 ng/ml olarak bulundu. Çalışmaya dahil edilen 5356 çocuk ve ergenin yalnızca %19.7’sinin (n=1056) D vitamini düzeyi yeterli olarak tespit edildi. 25(OH)D vitamini düzeyi ortalaması kırsal ve kentsel alanda yaşayanlarda benzer bulundu (p=0.673). Kızların 25(OH)D vitamini düzeyi ortalaması erkeklere göre anlamlı şekilde daha düşüktü (sırasıyla 18.5±13.07 ng/ml - 23.03±12.58 ng/ml) (p<0.001). Yaş gruplarına göre 25(OH)D vitamini düzeyi ortalaması en yüksek 1- 6 yaş grubunda görülürken (26.97±14.34 ng/ml), en düşük 7-17 yaş grubunda saptandı (15.77±9.19 ng/ml) (p<0.001). 25(OH)D vitamin düzeyi ortalaması en yüksek yaz mevsiminde (25.62±14 ng/ml) iken en düşük kış mevsiminde (16.95±11.76 ng/ml) tespit edildi (p<0.001). D vitamini düzeyi yaş, cinsiyet ve mevsim ile ilişkili bulundu. Sağlık profesyonelleri iskelet sistemi gelişimi için önemli bir dönemde olan çocuk ve ergenlerde D vitamini eksiliği sıklığını göz önünde bulundurmalıdır. Tüm mevsimlerde D vitamini desteği planlanarak, D vitamini eksikliğinin ve bunun getirdiği sağlık sorunlarının erkenden önüne geçilmelidir.

Kaynakça

  • 1. Haimi M, Kremer R. Vitamin D deficiency/insufficiency from childhood to adulthood: Insights from a sunny country. World J Clin Pediatr 2017; 6(1):1-9.
  • 2. Fernández Bustillo JM, Fernández Pombo A, Gómez Bahamonde R, Sanmartín López E, Gualillo O. Vitamin D levels in a pediatric population of a primary care centre: a public health problem? BMC Res Notes 2018; 11(1):801.
  • 3. Manios Y, Moschonis G, Hulshof T, et al. Prevalence of vitamin D deficiency and insufficiency among schoolchildren in Greece: the role of sex, degree of urbanisation and seasonality. Br J Nutr 2017; 118(7):550-558.
  • 4. González-Gross M, Valtueña J, Breidenassel C, et al. Vitamin D status among adolescents in Europe: the Healthy Lifestyle in Europe by Nutrition in Adolescence study. Br J Nutr 2012; 107(5):755-764.
  • 5. Mark KA, Dumas KJ, Bhaumik D, et al. Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1. Cell Rep 2016; 17(5):1227-1237.
  • 6. Braegger C, Campoy C, Colomb V, et al. Vitamin D in the healthy European paediatric population. J Pediatr Gastroenterol Nutr 2013; 56(6):692-701.
  • 7. Doğan N, Aydoğdu Çolak A, Güden N, Üstüner F. Vitamin D deficiency in children aegean region in Turkey. Cumhuriyet Medical Journal 2015; 37:17-22.
  • 8. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357:266–281.
  • 9. Cardoso S, Santos A, Guerra RS, et al. Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional study. BMC Geriatr 2017; 17(1):256.
  • 10. Saki F, Dabbaghmanesh MH, Omrani GR, Bakhshayeshkaram M. Vitamin D deficiency and its associated risk factors in children and adolescents in southern Iran. Public Health Nutr 2017; 20(10):1851-1856.
  • 11. Bucak İH, Almiş H. The Retrospective Analysis of Vitamin D Levels of Pediatric Patients in a Small City Center in Turkey. Sakarya Med J 2016; 6(3):136-140. 12. Karagüzel G, Dilber B, Çan G, ve ark. Seasonal vitamin D status of healthy schoolchildren and predictors of low vitamin D status. J Pediatr Gastroenterol Nutr 2014; 58(5):654-660.
  • 13. Alyahya KO. Vitamin D levels in schoolchildren: a cross-sectional study in Kuwait. BMC Pediatr 2017; 17(1):213.
  • 14. Gilbert-Diamond D, Baylin A, Mora-Plazas M, et al. Vitamin D deficiency and anthropometric indicators of adiposity in school-age children: a prospective study. Am J Clin Nutr 2010; 92(6):1446-1451.
  • 15. Aarskog D, Aksnes L, Markestad T, Rødland O. Effect of estrogen on vitamin D metabolism in tall girls. J Clin Endocrinol Metab 1983; 57(6):1155-1158.
  • 16. Stanczyk FZ, Clarke NJ. Measurement of estradiol--challenges ahead. J Clin Endocrinol Metab 2014; 99(1):56-58.
  • 17. Solak İ, Goksin Cihan F, Mercan S, Kethuda T, Eryılmaz MA. Evaluation of 25-hydroxyvitamin D levels in central Anatolia, Turkey.BioMed Research International 2018; (1):1-5.
  • 18. Sahin ON, Serdar M, Serteser M, Unsal I, Ozpinar A. Vitamin D levels and parathyroid hormone variations of children living in a subtropical climate: a data mining study. Ital J Pediatr 2018; 44(1):40.
  • 19. Andıran N, Çelik N, Akça H, Doğan G. Vitamin D deficiency in children and adolescents. J Clin Res Pediatr Endocrinol 2012; 4(1):25-29.
  • 20. Akman AO, Tumer L, Hasanoglu A, Ilhan M, Caycı B. Frequency of vitamin D insufficiency in healthy children between 1 and 16 years of age in Turkey. Pediatr Int 2011; 53:968–973.
  • 21. Sarma D, Saikia UK, Baro A. Vitamin D Status of School Children in and around Guwahati. Indian J Endocrinol Metab 2019; 23(1):81-85.
  • 22. Erol M, Yiğit Ö, Küçük HS, Bostan Gayret Ö. Vitamin D deficiency in children and adolescents in Bağcılar, İstanbul. J Clin Res Pediatr Endocrinol 2015; 7(2):134-139.
  • 23. Feizabad E, Hossein-Nezhad A, Maghbooli Z, Ramezani M, Hashemian R, Moattari S. Impact of air pollution on vitamin D deficiency and bone health in adolescents. Arch Osteoporos 2017; 12(1):34.
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular İç Hastalıkları
Bölüm Araştırma Makalesi
Yazarlar

Sevil Okan

Fatih Okan 0000-0002-7544-9051

Osman Demir

Yayımlanma Tarihi 25 Eylül 2020
Gönderilme Tarihi 20 Temmuz 2020
Yayımlandığı Sayı Yıl 2020

Kaynak Göster

APA Okan, S., Okan, F., & Demir, O. (2020). ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ. Sağlık Bilimleri Dergisi, 29(2), 114-118. https://doi.org/10.34108/eujhs.772031
AMA Okan S, Okan F, Demir O. ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ. JHS. Eylül 2020;29(2):114-118. doi:10.34108/eujhs.772031
Chicago Okan, Sevil, Fatih Okan, ve Osman Demir. “ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ”. Sağlık Bilimleri Dergisi 29, sy. 2 (Eylül 2020): 114-18. https://doi.org/10.34108/eujhs.772031.
EndNote Okan S, Okan F, Demir O (01 Eylül 2020) ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ. Sağlık Bilimleri Dergisi 29 2 114–118.
IEEE S. Okan, F. Okan, ve O. Demir, “ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ”, JHS, c. 29, sy. 2, ss. 114–118, 2020, doi: 10.34108/eujhs.772031.
ISNAD Okan, Sevil vd. “ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ”. Sağlık Bilimleri Dergisi 29/2 (Eylül 2020), 114-118. https://doi.org/10.34108/eujhs.772031.
JAMA Okan S, Okan F, Demir O. ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ. JHS. 2020;29:114–118.
MLA Okan, Sevil vd. “ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ”. Sağlık Bilimleri Dergisi, c. 29, sy. 2, 2020, ss. 114-8, doi:10.34108/eujhs.772031.
Vancouver Okan S, Okan F, Demir O. ÇOCUK VE ERGENLERDE D VİTAMİNİ DÜZEYİNİN YAŞ, CİNSİYET, YERLEŞİM YERİ VE MEVSİM İLE İLİŞKİSİ. JHS. 2020;29(2):114-8.