GELENEKSEL VE TAMAMLAYICI TIPTA APİTERAPİ

Yıl 2021, Cilt: 30 Sayı: 2, 200 - 203, 15.09.2021

Türkan Ekici Asuman Gölgeli

https://doi.org/10.34108/eujhs.654811

Cited By: 1

Öz

Apiterapi, arı ve kovan ürünlerinin tedavi amaçlı kullanılmasıdır. Geleneksel ve Tamamlayıcı bir tedavi yöntemi olan apiterapi ile sağlıklı yaşam desteklendiği gibi akut ve kronik bir çok hastalık tedavi edilebilir.
Apiterapi ürünleri, bal arısı (Apis meliferia L.) ürünleri; bal, propolis, arı poleni, arı sütü, arı zehiri, balmumu, apilarnil ve arı ekmeğidir. Bu ürünlerin çoğu asırlardan beri insanoğlunun beslenmesi için bir gıda maddesi olarak kullanıldığı gibi sağlık üzerine olumlu etkilerinden dolayı apiterapi dünya çapında her geçen gün rağbet gören ve yükselen bir değerdir. Bu derlemenin amacı apiterapötik ürünler ile sağlıklı yaşamı korumak, geliştirmek ve hastalıklar üzerine olan etkilerini ve tedaviye yönelik kullanım alanlarıyla beraber kazanımları vurgulamaktır.

Anahtar Kelimeler

apiterapi, apilarnil, arı ekmeği (perga), bal, polen

APITHERAPY IN TRADITIONAL AND COMPLEMENTARY MEDICINE

Öz

Apitherapy is the treatment of bee and hive products. As a traditional and complementary treatment, apitherapy supports healthy living and can treat many acute and chronic diseases.
Apitherapy products, include honeybee (Apismelifera L.) products; honey, propolis, bee pollen, royal jelly, bee venom, beeswax, apilarnil and beebread. Most of these products have been used as food for human nutrition for centuries, and because of its positive effects on health, apitherapy has become increasingly popular and worldwide valuable. The aim of this review is to preserve, improve and improve healthy lifestyles with apitherapeutic products and to emphasize their effects on diseases and their use in therapeutic areas.

Anahtar Kelimeler

Apitherapy, apilarnil, bee, bee bread (perga), honey, pollen.

Kaynakça

• KAYNAKLAR 1. Rice V Complementary and Integrative Medicine in Healthcare. Work. 2019 May 28.
• 2. El-Aidy W.K, Ebeid A.A, Sallam A.E.M, et all “Evaluation of propolis, honey and royal jelly in amelioration of peripheral blood leukocytes and lung inflammation in Mouse conalbumin-induced asthma model”, Saudi Journal of Biological Sciences 2015;(22):780 –788. 3. Gül A, Şahinler N. Balın yapısına ve kalitesine etki eden faktörler. IV. Ulusal Zeoteknik Bilim Kongresi, 1-3 Eylül 2004. Süleyman Demirel Üniversitesi, Isparta. 4. Allsop KA, Miller JB. Honey revisited: A reappraisal of honey in preindustrialdiets. Br J Nutr. 1996; 75:513-520. 5. Mutlu C, Erbaş M, Arslan Tontul S. Bal ve Diğer Arı Ürünlerinin Bazı Özellikleri ve İnsan Sağlığı Üzerine Etkileri Akademik Gıda 2017; 15(1): 75-83 6. Azman KF, Zakarria R, AbdAziz C, Osman Z, Al-Rahbi B. Tualang honey improves memory performance and decreases depressive - like behavior in rats exposed to loud noise stress. Noise Health. 2015;17(75):83-9. 7. Roberto M.M, Matsumoto S.T, Jamal C.M, Malaspina O. and Marin-Morales M.A.“ Evaluation of the genotoxicity/mutagenicity and antigenotoxicity/ antimutagenicity induced by propolis and Baccharis dracunculifolia, by in vitro study with HTC cells ”, Toxicology in Vitro 2016 Jun; 33: 9–15. 8. Bankova V. “Chemical diversity of propolis and the problem of standardization”, Journal of Ethnopharmacology 2005; 100:114–117. 9. Doğan N. ve Hayoğlu İ. Propolis ve Kullanım Alanları. HR. Ü.Z.F. Dergisi 2012;16(3): 39-48. 10. Viuda-Martos M, Ruiz-Navajas Y, Fernández-Lopez J, Perez-Alvarez JA. Functional properties of honey, propolis, and royal jelly. J Food Sci 2008 Nov:73(9):117–24. 11. Focht J, Hansen SH, Nielsen JV, van den Berg-Segers A, Riezler R. Bactericidal effect of propolis in vitro against agents causing upper respiratory tract infections. Arzneim Forsch / Drug Res. 1993; 43 (2): 921-923. 12. AmorosM Lurton E, Boustie J, Girre L. Comparison of the anti-herpessimplex virüs activities of propolisand 3 methylbut-2-enyl caffeate. J Nat Prod. 1994; 57: 644-647. 13. Khayyal MT, el-Ghazaly MA, el-Khatib AS. Mechanisms involved in the antinfl ammatory effect of propolis extract. Drugs Exp Clin Res. 1993;19 (5): 197-203. 14. Demirseren DD. New therapeutic options in the management of superficial fungal diseases.Dermatol Ther. 2019 Feb 12: e12855. 15. Onur E, Nalbantsoy A, Kışla D. İmmünoterapi ve propolisin kanser immünoterapisinde kullanım potansiyeli. Food and Health, 2018; 4(4):231-246. 16. Pasupuleti VR, Sammugam L, Ramesh N, Gan SH. Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits.Oxid Med Cell Longev. 2017; 2017:1259510 17. Al-Hariri M. Immune's-boosting agent: Immunomodulation potentials of propolis.J Family Community Med. 2019; 26(1):57-60. 18. Reis JS , Oliveira GB, Monteiro MC . Antidepressant- and anxiolytic-like activities of an oil extract of propolisin rats.Phytomedicine. 2014;21(11):1466-72. 19. Mohammadzadeh S, Shariatpanahi M, Hamedi M. Chemical Composition, Oral Toxicity and Antimicrobial Activity of Iranian Propolis, Food Chemistry, 2007;103: 1097–1103. 20. Bayrak N. Arı Ürünlerinin (Bal, Arısütü, Polen ve Propolis) Mikrofloralarının ve Antimikrobiyal Aktivitelerinin İncelenmesi, Yüksek Lisans Tezi, Fırat Üniversitesi Fen Bilimleri Enstitüsü, Elazığ, 2005: 56. 21. Sattler J.A.G, Melo, I.L.P.D, Granato, D. “Impact of origin on bioactive compounds and nutritional composition of bee pollen from southern Brazil: A screening study”, Food Research International 2015; 77: 82–91. 22. Ulbricht C, Conquer J, Giese N, et al. An evidence-based systematic review of bee pollen by the Natural Standard Research Collaboration. J Diet Suppl 2009; 6(3):290–312. 23. Şahinler N. Arı Ürünlerinin İnsan Sağlığı Açısından Önemi, M.K.Ü. Ziraat Fakültesi Dergisi, 2000; 5(1-2):139-148. 24. Garcia M, Perez-arquillue C, Juan Juan, M.I. ve Herrera, A. Pollen Analysis and Antibacterial Activity of Spanish Honeys, Food Science and Technology International, 2001; 7 (2): 155-158. 25. Santos HFD, Campos JF, Santos CMD, et al. Chemical Profile and Antioxidant, Anti-Inflammatory, Antimutage¬nic and Antimicrobial Activities of Geopropolis from the Stingless Bee Melipona orbignyi. Int J Mol Sci 2017 May 3;18 (5):pii: E953. 26. Han X, Shen T, Lou H. Dietary Polyphenols and Their Biological Significance Int. J.Mol.Sci. 2007;(8):950-988. 27. Saral Ö. Apiterapik Arı Ürünlerinin (bal, polen, propolis ve arı sütü) Biyoaktif Özellikleri ve Karaciğer Hasarını Önlemedeki Rolleri, Doktora Tezi, Karadeniz Teknik Üniversitesi, Fen Bilimleri Enstitüsü, Trabzon, 2013: 106. 28. Morgano M.A, Milani R.F, Martins M.C.T. and Rodriguez-Amaya D.B,“ Determination of water content in Brazilian honeybee-collected pollen by Karl Fischer titration”, Food Control 2011; 20:1604-1608. 29. Ramadan MF, Al-Ghamdi A. Bioactive compounds and health-promoting properties of royal jelly: A review. J Funct Foods. 2012;4(1):39-52. 30. Albert S, Bhattacharya D, Klaudiny J, Schmitzova J, Simuth J. The family of major royal jelly proteins and its evolution. J Mol Evol. 1999;49:290-297. 31. Tamura S, Kono T, Harada C, Yamaguchi K, Moriyama T. Estimation and Characterisation of Major Royal Jelly Proteins Obtained From The Honeybee Apis merifera, Food Chem, 2009; 114(4):1491–1497. 32. Uçar M. Arı Sütünün Diyabet, Tümör Oluşumu ve Metabolik Sendrom Üzerine Etkisi. Türk Sağlık Bilimleri Dergisi 2018;(3) 2: 101-112 33. Temamoğulları F.K, Aral F, Demirkol R. Erkek Farelerde Arı Sütünün Uzun Süreli Uygulanmasının Bazı Spermatolojik Özellikler Üzerine Etkisi. Fırat Üniversitesi 2006; 20(5):341-344 34. Münstedt K, Bargello M, Hauenschild A. Royal jelly reduces the serum glucose levels in helathy subjects. Journal of Medicinal Food 2009;12(5): 1170-1172 35. Hattori N, Ohta S, Sakamoto T, Mishima S, Furukawa S.Royal jelly facilitates restoration of the cognitive ability in trimethyltin-intoxicated mice.Evid Based Complement Alternat Med. 2011; 2011:165968. 36. Guo H, Saiga A, Sato M, Miyazawa I, Shibata M. Royal jelly supplementation improves lipoprotein metabolism in humans. Journal Of Nutritional Science And Vitaminology, 2007; 53: 345-348. 37. Jo M, Park M.H, Kollipara P.S. Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway. Toxicology and Applied Pharmacology 2012; 258(1): 72-81. 38. Hossen MS , Shapla UM , Gan SH , Halil MI .Impact of Bee Venom Enzymes on Diseases and Immune Responses.Molecules. 2016;22(1). pii: E25. 39. Son D.J, Lee J.W, Lee Y.H, et all. Therapeutic Application of Anti-Arthritis, Pain-Releasing, and Anti-Cancer Effects of Bee Venom and Its Constituent Compounds, Pharmacol. Ther, 2007; 115( 2):246–270. 40. Silva J, Monge-Fuentes V, Gomes F. Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools.Toxins (Basel). 2015;17(8):3179-209. 41. Scala E, Pirrotta L , Uasuf CG, et all. Aedes communis Reactivity Is Associated with Bee Venom Hypersensitivity: An in vitro and in vivo Study. Int Arch Allergy Immunol. 2018;176(2):101-105. 42. Schmidt J.O. Chemical composition and application: Bee Products: Properties, Applications,and Apitherapy, Edited by Mizrahi A, Lensky Y. Springer Science & Business Media. 1997; 15-27. 43. Garnier N, Cren-Olive C, Rolando C, Regert M. Characterization of Archaeological Beeswax by Electron Ionization and Electrospray Ionization Mass Spectrometry. Analytical Chemistry. 2002 Oct;1:74(19):4868-4877 44. Kimpe K. Jacobs PA. Waelkens M. Mass spectrometric methods prove the use of beeswax and ruminant fat in late Roman cooking pots. Journal of chromatography. 2002 Aug 30 ;968 (1-2):151-160. 45. Fratini F, Cilia G, Turchi B, Felicioli A. Beeswax: A minireview of its antimicrobial activity and its application in medicine.Asian Pac J Trop Med. 2016;9(9):839-843 46. Giampieri F, Gasparrini M, Forbes-Hernández TY. Beeswax by-Products Efficiently Counteract the Oxidative Damage Induced by an Oxidant Agent in Human Dermal Fibroblasts.Int J Mol Sci. 2018;19(9). pii: E2842. 47. Cornara L, Biagi M, Xiao J, Burlando B. Therapeutic Properties of Bioactive Compounds from Different Honeybee Products.Front Pharmacol. 2017;8:412. 48. Artık N, Konar N. Arı Ürünleri ve Apiterapi-2: Arı Ürünlerinden Propolis, Polen ve Apilarnil Bileşimi. Küçükersan MK, editör. Arıcılık, Arı Ürünleri ve Apiterapi. 1. Baskı. Ankara: Türkiye Klinikleri; 2018. p.20-5. 49. Kırk E, Anderson M.J, Carroll T. S, et al. Hive-stored pollen of honey bees: many lines of evidence are consistent with pollen preservation, not nutrient conversion Molecular Ecology. 2014; 23: 5904–5917 50. Combey R. Microbial and qualitative analyses of stingless bee bread using dry preservation methods. European Journal of Zoological Research. 2017; 5 (1):45-50. 51. Zuluaga C.M, Serrato J.C. and Quicazan, M.C. Chemical, nutritional and bioactive characterization of colombian bee-bread. Chemical Engineering Transactions 2015;43: 175-180. 52. Kaplan M, Karaoğlu Ö, Eroğlu N, and Silici S. Fatty Acid and Proximate Composition of Bee Bread. Food Technol. Biotechnol. 2016; 54 (4): 497–504 53. Nagai T, Nagashima T, Myoda T, Inoue R. Preparation and functional properties of extracts from beebread. Nahrung / Food 2004;48(3):226-229 54. Ivanisova E, Kacaniova M, Francakova H, Petrova J. and Hutkova, J. Bee Bread- Perspectıve Source of Bioactive Compounds For Future. Potravinarstvo Scientific Journal for Food Industry. 2015;9 (1):592-598. 55. Abouda Z, Zerdani I, Kalalou I, Faid M, Ahami M.T. The antibacterial activity of Moroccan bee bread and bee-pollen (fresh and dried) against pathogenic bacteria. Research Journal of Microbiology. 2011; 6(4):376-384. 56. Pr Sobral F , Calhelha RC , Barros L, et al. Flavonoid Composition and Antitumor Activity of Bee Bread Collected in Northeast Portugal. Molecules. 2017:22(2). pii: E248. 57. Audisio M.C, Terzolo H.R, Apella M.C. Bacteriocin from honeybee beebread Enterococcus avium, active against Listeria monocytogenes. Applied and Environmental Microbiology. 2005;71(6): 3373- 3375. 58. Vásquez A, Olofsson T.C. The lactic acid bacteria involved in the production of bee pollen and bee bread.J.Apic. Res. 2009; 48: 189-95.