Anthrax'ın Patojenitesi

Öz

insan, çeşitli evcil ve vahşi hayvanlarda ekseriya akut, septi­ s'ernik karekterde seyreden anthrax hastalığı bilhassa çift tırnaklı hayvanlarda ani ölüm husule getirir. Ot yiyen hayvanlar bu has­ talığa daha çok yakalanırsada hayvanat bahçelerinde ki birçok domuz, mink, fil, deve kuşu, köpek ve diğer karnivorlar arasında hastalık çıktığı tesbit edilmiştir. Sterne (25) kuşların ve hatta kur­bağa ve balıklarında infekte edilebileceklerini bildirmiştir. Bu has­ talığa karşı çeşitli hayvan türlerinin hassasiyetleride değişiktir. Sterne (25) diğer koyun ırklarının aksine cezair koyunlarının ve domuzların anthrax'a karşı oldukca dirençli olduklarını, Walker ve arkadaşları (28) domuzların özellikle üzerinde yaptıkları tecnibelere gere cüce domuzların bu hastalığa karşı dirençli olduklarını ve bu hayvanlarda sporların çoğalmasını önleyici bir faktörün mev­cut olduğunu bildirmişlerdir.

Anahtar Kelimeler

• M. Nabi EMRE
• Anthrax
• Anthrax
• 1972
• Etlik Mikrobiyoloji Dergisi

Pathogenesis of Anthrax

Öz

İt has been given details about the principal factors in the pat­ hogenicity of anthrax and the mechanism of anthrax infection.

Kaynakça

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4. Berdjis, C.C., Gleiser, C.A., and Hartman, H.A., 1963 : Experimental pa­ renteral anthrax in /ı/ıacaca Mu l a tta . - Brit. J. Ex p . Pa th . 44, 1 Ol - 115 .
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6. Burrows, W., Moulder, J.W ., Lewert, R.M., 1963 : Bacillus. - The spor forming Aerobes in Textbook of Microbiology. - 7th ed i t io n . - W.B. Soun­ ders Co m pany . - Philadelphia and Lo ndo n . P. 688 - 696 .
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8. Fitzpatrick, D.F., Walker, J.S., Rlıian, M.A., Klein, F. and Lincoln, R.E ., 1962 : Changes in bloocl constituents and evidence of central nervous i n vo l ve men t resulting fronı anthrax toxin. - J. the Tennessee- Ac ede my of Scie nses . 38, 67 .

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19. Rhi,ın, M., Riley, J.M., Wolfe, V.L., and Simmons, A.H., 1963 : Change in virulence of Bacillus anthracis spores as affected by solids and Challen­ ge route. - J. İnfect. Dis. 112, 187-193.
20. Ross, J.M., 1957 : The pathogenesis of anthrax following the adminis­ tration of spores by the respiratory route. - J. patlı'., Bact. 73, 485-494.
21. Sawyer, W.D., Kuehne, R.W. and Gochenour. W.S., Jr., 1965 : Effect of egg yolk and phosphatides on anthrax infection of rats and guinea - pigs. . Proc. Soc. Exp. Biol. Med., 118, 105 - 108. Ref. Vet. Bull. 35, 1965, 2083.
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25. Thorne, C.B., Molnar, D.M., and Strage, R.E., 1960 : Production of toxın invlvo by B. anthracis and its separation into two com po nents . - J. of Bact. 79, 450 - 455.
26. Trnka, z., Malek, P., Sterzl, J. and Kolc, J., 1958 : (Experimental con t­ ributions to the lymphatic pathogenesis of anthrax i nfe ct io n ) . - Schweiz. Z. All g. Path. 21, 1082 - 1095. Ref . Vet. Bull., 29, 1959, 1281.
27. Walker, J.S., Klein, F., Lincoln, R.E. and Fernelius, A.L., 1967 : A unique defence mechanism against anthrax demonstrated in clwarf sw ine . - J. Bact. 93, 2031 - 2032.
28. Watson, D.W., Cromartie, W .J., Bllom, \V.L., Kegeles, G. and Heckley, R.J., 1947 : Studies on infection with Bacillus anthracis 111 . Chemical and İm­ munological properties of the protective antigen in crude extracts of ski,. lesions of B. anthracis. - J. of. İnfect. Dis. 80, 27 - 40.
29. Young, G.A., Jr., Zelle, M.R., and Lincoln, R.E;., 1946 : Respiratory Pat­ hogenicity of Bacillus anthracis spo res . 1. Methods of study and observa­ tions on pa thogenes is . - J . of İnfct. Diseas . 79, 233 - 246.