Kanatlı Hayvanlarda Mukozal Bağışıklık

Yıl 2020, , 93 - 100, 07.06.2020

Zeynep Şık

https://doi.org/10.35864/evmd.628318

Öz

Antijenler vücuda mukozal alanlardan girer.
Enfeksiyonlar mukozalarda oluşur ve yayılır. Mukozal lenfoid dokular (MALT),
spesifik ve nonspesifik bağışıklığı birlikte uyararak antijenleri giriş yerinde
yok ederler ve antijenin yayılmasını engeller. Kanatlı hayvanlar sindirim
(GALT), solunum (Harderian bez, CALT, NALT, BALT) ve genital sistemde bulunan
mukozal lenfoid dokuları ile gelişmiş bir mukozal bağışıklık sistemine
sahiptir. Ancak kanatlı hayvanların mukozal lenfoid dokularının özellikleri ve
savunma mekanizmalarına dair sınırlı bilgi vardır. Bu derleme kanatlı
hayvanlarda bulunan mukozal lenfoid dokuları birlikte sunarak enfeksiyonların
önlenmesindeki rolüne ve yeni mukozal aşı stratejileri geliştirilmesine katkıda
bulunacaktır.

Anahtar Kelimeler

BALT, CALT, GALT, Kanatlı, NALT

Teşekkür

Bu derleme makalesinin hazırlanmasında desteğini esirgemeyen danışman hocam sayın Prof. Dr. Mehmet AKAN’a teşekkür ederim.

Mucosal immunity in poultry

Öz

Antigens enter the body throught the mucosal surfaces. Infections occur and spread in mucosal surfaces. Mucosal lymphoid tissues (MALT), prevent specific and nonspecific immunity from spreading the antigens at the site of introduction by stimulating together. Poultry animals have a mucosal immune system developed with digestion (GALT), respiratory (Harderian gland, CALT, NALT, BALT) and mucosal lymphoid tissues found in the genital system. However, there are limited information about the properties and defense mechanisms of mucosal lymphoid tissues of poultry. This review will contribute to the role of prevention of infections and the development of novel mucosal vaccine strategies by presenting mucosal lymphoid tissues in poultry.

Anahtar Kelimeler

BALT, CALT, GALT, NALT, Poultry

Kaynakça

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