Gnotobiyotik Yaşantı

Mustafa Arda

EN TR

Gnotobiyotik Yaşantı

Öz

Eskidenberi ilmi araştırmaların ekserisi hayvanlar üzerinde yapılmakta ve bu nedenle de, deneme hayvanıanna çok sayıda ihtiyaç hasıl olmaktadır. Nitekim, Robert Koclı, kendi adı ile anılan
ve 4 maddeden ibaret olan, Kodı Postulat'ında «izole edilen etkenler hassas hayvaniara şırınga edilince hastalık meydana getirmelidirler » demektedir. Bu çağlarda başlayan deneme hayvanı kullanma tutkusu, zamanımız ilim adamlannda da ayni kuvvette bulunmaktadır.

Anahtar Kelimeler

Kaynakça

1 - Aberbathy, R.S. and Landy, J.J; (1967): Increased Resistence to Endo. toxin in Germ Free Guinea pigs. Proc. Soc. Exp. Med., 124 : 1279. 1283.
2 - Abrams, G.D. (1969) : The Normal Microbial Flora and Resistance of the Small Intestine. Advence Study Institute. The Germfree Animal as a Tool in Research Leuven, Belgium. Abstract No. 12.
3 - Asano, T. (1967): Inorganic lons in Secal Content of Gnotobiotic Rats. Proc. Soc. Exp. Biol. med:, 124 : 424 . 430.
4 - Betts, A,O. (1969): Some Uses of Gnotobiotic Farm Animals. Adven. ced Study Institute. The Germfree Animal as a Tool in Research. Le. uven, Belgium. Abst ract No. 39.
5 - Bleby, J. (1967): Specific Pathogen Free Animals. The UFAW Hand_ book on the Care and Management of Laboratory Animals, 201- 215: Third ·ed. Livirgstone
6 - Burmester, B.R. and Waters, N.F. (1955) : The Role of the Infected Eggs in the Transmission Visceral Lymphomatosis. Poult. Sci., 34: 1415- 1429.
7 - Calhoon, J.R. and Matthews, P.J. (1964): A Method for Initiating a Colony of Specific Pathogen Free Gıinea Pigs. Lab. Aniaml Care 14 : 388-394.
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9 - Cohendy, M. (1912) : Experineces surla vie sans Microbes. Ann. Inst. Pasteur, 26: 106 _ 137.
10 - Craven, J. and Miniats, O.P. (1969) : Antagonism Between Escherichia Coli Strains in Dualinfected Gnotobiotics Pigs. Advances Study Instıtu te. The Germfree animal as a Tool in Research Leuven, Belgium. Abt. ract No. 6.
11- Davey, D.G. (1962) : Use of Pathogen Free Animals. Proc. Roy. Soc. Med., 55 : 256 _ 259.
12 - Dinsley, M. (1967): Germ Free Animals. The UFAW Handbook on the Care and Manegement of Laboratory Animals, Ihird ed. 216 _ 238.
13 - Dinsley, M. 1969): Genetic Manegement in Gnotobiotic Colonies. Advance Study Institute, The Germfree Animal as a Tool in Research,Leuven, Belgium. Abstract No. 6
14 - Duclaux, E. (1.885) : Presentee par M. Pasteur, Physilogie Vegetale. sarla germination dans un sol richie en matiers organiques, mais exempt de microbes. C.r. hebd. Searc. Acad. Sci., Paris. 1.00-66-68. Site. Reyniers , J.A. (1969 ): (Pure ·culture concept and gnotobiotics.) Ann. N.Y. Acad. Sci., 78 : 3- 16
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16 - Fitzgerald, G.R. and Pollard, M. (1967) : Interferon Production by Germ Free Mice. Proc. Soc. Exp. Biol. Med., 126: 245- 249.
17 - Forbes .M., Park, J.T. and Lev,·, M. (1959) : Role of the Intestlnal Flora in the Growth response of Chicks to Dietary Penicillin. Ann. Y. Acad. Sci. , 78: 321-327.
18 - Foster, H.L. (1961): Development of Specific Pathogen Free and Germ Free Animals . Bio_ Medical Review. 1: 77 _ 85.
19 - Foster, H.L. and Black, C.L. (1969): Utulizing the Germfree Rat in the Investlgation of Clinical Manifestations Caused by a Filtrable Agent. Advance Study Institute. The Germfree Animal as a Tool in Research. Leuven, Belgium. Abstract No. 23.
20 - Glimstedt, G. (1936): Bacterienfreie Meerschweinchen. Acta Path. Microbiol. Scand. Suppl., 30: 1_ 295. Site. Reyniers, J. A. (1959): Pure Culture Concept and Gnotobiotics. Ann. N.Y. Acad. Sci., 78: 3 .16.
21 - Gordon, H.A. (ı959) : Morphological and Physiological Characterlzation of Germ Free Life. Ann. N.Y. Acad. Sci., ·78: 208.220.
22 - Grisemer, R.A. and Gibson, J.P. (1963): The Gnotobiotic Dog. Lab. Ani mal Care, 13 (pt): 648.649.
23 - Gustafsson, B.E. (1948): Germ Free Rearing of Rats. General Techni ques. Acta Path. Microbiol. Scand .suppl. 73 : 1 ,130.
24 - Gustafsson, B.E., and Laurell, C.B. (1958): Gamma Globilin in Germ Free Rats. J. Exp. Med. 108: 251. 258.
25 - Gustafsson, B.E., and Laurell, C.B. (1959): Gamma Globulin Productioin Germ Free Rats after Bacteriel Contamination. J. Exp. Med. 110: 675-684.
26 - Gustafsson, B.E. (1959) : Lightweight Stainless Steel System for Re. aring Germ Free Animals. Ann. N.Y. Acad. Sd. 78 : 17. 28.
27 - Hall, \V.J., Legenhausen, D.H. and l\lcDonaJd, A.D. (1949) : Studies on Fowl Typhoid. L Nature and Disseınination . Poult .Sci. 23 : 344. 362.
28 - Harven, E. (1964) : Virus Particles ın Thymus of Conventional and Germ Free Mice. J. Exp. Med. 120 : 857 . 868.
29 - Henthorne, R.D. and Kester, W.O. (1959) : Diseases Free Laboratory Animals Related to Germ free Life.· Ann. N.Y. Acad. Sel. 78 : 276 _ 280.
30 - Hudson, J.A. and · Luckey, T.D. (1964) : Bacteria. Induced Morphologic Changes. Proc. Soc. Exp. Biol. Med. 116 : 628 - 631.
31 - Jensen, S.B., Mergenhagen, S.E., Fitzgerald, R.J. and Jordan, H.V. (1933): Susceptibility of Conventinoal and Germfree Mice to Lethal Effects of Endotoxin. Proc. Soc. Exp. Biol. Med. 113 : 710. 714.
32 - Joshi, N., Blackwood, A.C. and Dale, D.G. (1964) : A Simple Chemical Method for Detection of Leakes in Flexeble Isolator- Canad. J. Comp. Med. and Vet. Sci. 28 : 128. 133.
33 - Kelly, M.G., Newton, W.L. and O'Gara, R.W. (1963) : Susceptibility of Newborn Germfree Mice to Tumor Induction by 3. Methylcholanthrene. Cancer Res. 23 : 978 _ 982. Site. The Year Book of Veterinary Medicine. (1964), Vol. 2, 361. 362.
34 - Küster (1915) : Die Gewinnung, Haltung und Aufzucht Keimfreier Tle. re und İhre Bedeutung für die Erforschung Natürlicher Lebensforgan. ge. Arbeiten Kaiser. Gesund. 48 : 1 _ 79.
35 - Loesche, W,J. (1968) : Protein and Carbohydrate Composttion of Cecal Content of Gnotobiotic Rat and Mice. Proc. Soc. Exp. Biol. Med. 128 : 195.199.
36 - Loesche, W.J. (1968) : Accumulation of Endogenous Protein in the Ce. cum of the Germfree Animals. Proc. Soc. Exp. Biol. Med. 129 : 380 _ 384.
37 - Luckey, T.D. (1959) : Nutrition and Biochemistry of Germfree Chicks. Ann. N.Y. Acad. Sci. 78 : 127.165.
38 - Luckey, T.D. (1965) : Effects of Microbes on Germfree Animals.Advan. ces in Applied Micobil. 7 : 169 _ 223.
39 - Mandel, L., Miler, I. and Moravek, F. (1969) : The Effet of Ionizing Ra. diation on Natural Resistance Factors in Germfree Piglet. Advanced Study Institute. The Germfree Animal as a Tool in Research. Leuven, Belgium. Absctract. No. 37.
40 - Metchnikoff, E. 1903) : E'tudes sur la flore Intestinale. Ann. de L'Institute Pasteur. XXIII. 929. Site. Reyniers, J.A. (1959) : Pure Culture Concopt and Gnotobiotics. Ann. N.Y. Acad. Sci. 78: 3 -16.
41 - Midtvedt, T. (1969) : Opsinizing and Bacteriolytic Effects of Sera from Gnotobiotics and Conventionalized Ra ts on 32 P- Labelled E. coli. Ad. vanced Study Institute, The Gerfree Animal as a Tool in Research. Leu. ven, Belgium. Abstract No. 35.
42 - Mirand, F.A. (1969) : The Response of a Polycythemic Virus in Germfree Mice Advaced Study Institute. The Germfree Animal as a Toll In Reseach . Leuven, Belgium. Abstract No. 24.
43 - Miyakawa, M., Iijima, S., Kobayashi, R., Tajima, M., Isomur, N., Shini. zu, T., Kobayashi, I. and Asano, M. (1954) : Report on Succes of Long. term Rearing of Germfree Guineapigs. Trans. Soc. Pathol. Japan. 43 : 450. Site. Reyniers, J .A. (1959) : Pure Culture Concept and Gonotobio. tics. Ann. N.Y. Acad. Sci. 78 : 3 _ 16.
44 - Miyakawa, M. (1959) : The Miyakawa Remote_ Control Germfree Rea. ring Unit. Ann. N.Y. Acd. Sci. 78 : 37- 46.
45 - Miyaknwa, M. (1959) : The Lymphat 'ı c System of Germfree Guineapıgs. Ann. N.Y. Acad. Sci. 78 : 221 _ 236.
46 - Morris, J.H. (1963) : Management of Specific Pathogen Free Guineapig Colony. Lab. Animal :are, 13 : 96 _ 100.
47 - Nance, F.Cohn, ı., Heneghan, J.B., Bornside, G.H., Kline, Crook, J.N., Tedesco, V.E. and Rusca, J. (1969) : Ge rmfı·ee Dogs in the Study of the Surgical phys'ology of the Gastrointestinal Tract. Advanced Study Institute. The Germfree Animal as a Tool in Research. Leuven, Belgium. Abst. ract No. 19.
48 - Nencki, M. (1886) : Bemerkungen zur einer Bemerkung Pasteur's. Na. unyn. Schmİedeberg Arch. exp. Path. Pharmak., 20 : 385. 388. Site. Dins. !ey, M. (1967) : Gemıfree Animals. The UFAW Handbook on the Care and Manegement of Laboratory Anima ls. 216 . 238. Third ed.,
49 - Nuttal, G.H.F. und Thierfelder, H. (1897) : Thierisches Leben ohne Bak. terien in Verdauungskanal. (III. Mitteilung). Versuche an Hüchnern. Hoppe. Seyler's Z. Physiol. Chem. 23 : 231. 235. Site .Reyniers, J.A. (1959) : Pure Culture Concept and Gnotobiotics. Ann. N .Y. Acad. Sci. 78: 3-16.
50 - Paget, G.E. (1962) : Pathologic State of Spesific Pathogen Free Ani. mals. Proc. Roy. Soc. Med. 55 : 262 _ 263.
51 - Pasteur, L. (1885) : Observastions Relatives a la note precedente de M. Duclaux. C.r. Hebd. Seans. Acad. Sci. Paris, 100, 68. Site. Dinsley, M. (1967 ) : Germfree Animals. The UFAW Handbook on the Care and Manegement of Lab. Animals. S. 216 _ 238.
52 - Payzın , S. ( 1968) : Gnatobiyoloji ve İmmunolojideki yeri. Mikrobioloji Bulten 2 : 112 _ 118.
53 - Peter, W·.L. (1962) : Provision of Pathogenfree Animals. Proc. Roy. Soc. Med. 55 : 253- 256.
54 - Phillips, A.W. and Smith, J.E. (1959) : Germfree Aniınal Technique and Their Applicaions. Advances in Applied Microbiol. 1: 141 _ 174.
55 - Phillips, B.P., Wolfe, P.A. aml Gordon, H.A. (1959) : Studies on Rearing the Guineapigs Germfree. Ann. N.Y. Acad. Sü 78 : 183- 207.
56 - Philiips, B.P. and Wolfe, P.A. (1959) : The Use of the Germfree Guinca. pigs in the Studies on the Microbial Interrealtionships in amoepiasis . Ann. N.Y. Acad. Sci 78 : 308- 313.
57 - Pleasents, J.R. (1959) : Rearing Germfree Cesarien- Borne Rats, Mice and Rabbits Through Weaning. Ann. N.Y. Acad. Sci. 78 : 116 _ 126.
58 - Pleasents, ,J.R., Wostman, B.S. and Zimmerman, D.R. (1964) : Improved Handrearing Methods for Small Rodents. Lab. Animal Care. 14 : 37 _ 47.
59 - Pollerd, M. and Salomon, C. (1963) : Oncogenic Effect of Methylcholan. threne in Newborn Germfree Mıce. Proc. Soc. Exp. Biol. Med., 112 : 256-259.
60 - Pollard, M. and Teah, B.A. (1963) : Spontanous Tumors in Germfree Rats. J. N at. cancer Inst. 31. : 457 _ 465. s•te. The Year BOOK of Vet. Med. (1964). 2 : 360.
61 - Pollard M. and Matsuzawa, T. (1964) : Radiation. Induced Leukemla in Germfree Mice. Proc. Soc. Exp. Biol. Med. 116 : 967. 971.
62 - Pollard, M. (1965)Germfree Animals and Biological Research. Sci. 145 : 247- 251.
63 - Pollard, M. (1967) : Application of Germfree Animals to Problems in Comperative Medicine. Advances in Vet. Sci. 11: 139. 157.
64 - Pollard, M. (1969) : A Comparison of Neoplasma Induced in Germfree Rats by Chemical and Viral Oncogenic Agents . Advanced Study Insti tute. The Germfree Animal as a Tool in Research. Leuven, Belgium. Abstract No. 21.
65 - Price, J.E., Millen, T.W. and Alberst, J .O. (1954) : Studies on N ewcast. le Disease. IV. The Presence of Newcastle Disease vırus in Eggs of Hens Vaccinated with Live Vaccine. J. Amer. Vet. Med. Asso., 116 : 54. 55·.
66 - Przjalkowski, Z. (1939) : Parasitism in Germfree ·Laburatory Animals. Advances Stundy Institute. The Germfree Animal as a Tool in Research. Leuven , Belgium · Abstract No. 7.
67 - Raibaud, P., Dickinson, A.B., Sacquet, E., Charlier, H. at Mocguet, G. (1966) : La Microflora du Tube Digestif du Rat. IV. Implantation Cont. role chez le rat Gnotobiotique de differents Genres Microbiens Isoles du Rat Conventional. Ann. d'Institut Pasteur, 111: 193. 210.
68 - Reyniers, J.A. (1942) : Rearing of Cesarean borne M. rhesus Monkey under Sterile Conditions. J . Bact., 43 : 778. Site. Reyniers, . J :A. ( 1959) : Pure Culture Concept and Gnotobiotics. Ann. N.Y. Acad. Sci. 78 : 3. 16.
69 - Reyniers, J.A. and Trexler, P.C. (1943) : The Germfree Tecnique and its Application to Rearing Animals free from Cuntamination. In' Micrurgical and Germfree Methods, pp. 114 .143. Ed. Reyniers, J . Spring. field, III. Thomas. Site . Reyniers, J.A. (1959) : Pure Culture Concept and Gnotobiotics. Ann. N.Y. Acad. Sci. 78 : 3 _ 16.
70 - Reyniers, J.A. (1957) : The Production and Use of Germfree Animals in Experimental Biology and Medicine. Amer. J. Vet . Res., 18:678 . 687.
71 - Reyniers, J.A._ (1959): Pure Culture Concept and Gnotobiolics. Ann. N. Y. Acad . Sci. 78 : 3 . 16.
72 - Reyniers J. .A. (1959) : Desing and Operation of Apparatus for rearing Germfree Animals . Ann. N.Y. Acad. Sci. 78 : 47. 79 .
73 - Reniers, J.A. and Sacksteder,M.R. (1959) : Tumorigenesis and the Germfree Chickens. A Preliminary Report. Ann. N .Y. Acad. Sci. 78 : 328-353.
74 - Saba, T.M., Filkins, J.P. and Luzio, N-R.. (1967) : Phagocytic and Opsonic Activites of Germfree Rats. Proc. Soc. Exp. Bio •. Med. 125 : 634. 636.
75 - Schaedler, R.W. and Dubos, R .J. (1961) : The Susceptibility of Mice to Bacterial Endotoxin. J. Exp. Med. 113 : 359 _ 570.
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77 - Skelly, B.J., Trexler, P.C. and Tanami, J. (1962) : Effect of Clostridiuın Species upon Cecal Size of Gnotobiotic Mice. Proc. Sac. Exp. Blo!. Med 110 : 455 - 458.
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82 - Trexler, P.C. and Skelly, B.J. (1963) : Microbic Flora for the Gnotobiotic Laboratory AnimaL Lab. Animal Care 13 : 609- 615.
83 - Uhr, J .W., Dancis, J. and Finkelstein, M.S. (1963) : Passage of Bacte . riophage 0 X 174 Across Placenta in Gulneapig. Proc. Sac. Exp. Biol. Med-. 113 : 391 . 394.
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86 -- Wagner, M. (1969) : Immunization Against Experimental Dental Carles in Gnotobiotic Rats. Advances Study Institute. The Germfree Aniaml as a Tool in Research. Leuven, Belgiuın. Abstarct No. 16.
87 - Vandeputte, M., Sacquet, E . and DeSomer, P. (1969) : Effect of Polyo. mavirus on Lymphold Tissue of Germfree and Conventional Mlce. Ad. vanced Study Institute. The Germfree Animal as a Tool in Research. Leuven Belgium. Abstract. No. 22.
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92 Young·, G.A. (1957) : Özel Görüşmeler. Nebraska , Ziraat Fakültesi. Animal pathology Dept. Nebr. U.S.A.

Ayrıntılar

Birincil Dil

Türkçe

Konular

Veteriner Bilimleri

Bölüm

Derleme

Yazarlar

Mustafa Arda Bu kişi benim
Türkiye

Yayımlanma Tarihi

1 Aralık 1970

Gönderilme Tarihi

1 Aralık 1970

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 1970 Cilt: 3 Sayı: 9-10

IZ

https://izlik.org/JA82MD35TR

Kaynak Göster

RIS / Bibtex

APA

Arda, M. (1970). Gnotobiyotik Yaşantı. Etlik Veteriner Mikrobiyoloji Dergisi, 3(9-10), 110-141. https://izlik.org/JA82MD35TR

AMA

1.Arda M. Gnotobiyotik Yaşantı. Etlik Vet. Mik. Derg. 1970;3(9-10):110-141. https://izlik.org/JA82MD35TR

Chicago

Arda, Mustafa. 1970. “Gnotobiyotik Yaşantı”. Etlik Veteriner Mikrobiyoloji Dergisi 3 (9-10): 110-41. https://izlik.org/JA82MD35TR.

EndNote

Arda M (01 Aralık 1970) Gnotobiyotik Yaşantı. Etlik Veteriner Mikrobiyoloji Dergisi 3 9-10 110–141.

IEEE

[1]M. Arda, “Gnotobiyotik Yaşantı”, Etlik Vet. Mik. Derg., c. 3, sy 9-10, ss. 110–141, Ara. 1970, [çevrimiçi]. Erişim adresi: https://izlik.org/JA82MD35TR

ISNAD

Arda, Mustafa. “Gnotobiyotik Yaşantı”. Etlik Veteriner Mikrobiyoloji Dergisi 3/9-10 (01 Aralık 1970): 110-141. https://izlik.org/JA82MD35TR.

JAMA

1.Arda M. Gnotobiyotik Yaşantı. Etlik Vet. Mik. Derg. 1970;3:110–141.

MLA

Arda, Mustafa. “Gnotobiyotik Yaşantı”. Etlik Veteriner Mikrobiyoloji Dergisi, c. 3, sy 9-10, Aralık 1970, ss. 110-41, https://izlik.org/JA82MD35TR.

Vancouver

1.Mustafa Arda. Gnotobiyotik Yaşantı. Etlik Vet. Mik. Derg. [Internet]. 01 Aralık 1970;3(9-10):110-41. Erişim adresi: https://izlik.org/JA82MD35TR

Gnotobiotism

Öz

Gnotobiyotik Yaşantı

Öz

Anahtar Kelimeler

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

IZ

Kaynak Göster