İnfeksiyöz Bronşitis Virusu'nun Tracheal Organ Kültürlerine Etkisi: Işık Mikroskobik İnceleme

Öz

IBV M41 referens suşunun infektivite titrasyonu tracheal organ kültürlerinde yapıldı ve Ml'de %50 siliostatik doz olarak ifade edildi. lB M41 suşunun titresi Log10 5,48 CD50/ml idi. Virus-infekte tracheal halkaların histopatolojik incelemesinde kinosilyumlarda kayıp, epitel katmanda yassılaşma ve epitel hücrelerinde yuvarlaklaşma, piknoz ve dökülmeler gözlendi.

Anahtar Kelimeler

• IBV
• tracheal organ kültürleri
• histopatoloji
• İnfeksiyöz Bronşitis
• Ayşin ŞEN
• Mihriban ÜLGEN
• Deniz MISIRLIOGLU
• 1996
• Etlik Veteriner Mikrobiyoloji Dergisi

Effect Of Infectious Bronchitis Virus On The Tracheal Organ Cultures: Light Microscopic Examination

Öz

Infectivity titration of IBV M4 1 strain (reference virus) were done in tracheal organ cultures and expressed as the fıfty per cent ciliostatic dose (CD50) per ml. The teter of the IBV M41 strain was log ı O 5,48 CD50/ml. Histopathological examination of virus -infected tracheal rings showed loss of kynocilum, fiattening of lamina epithelialis and pyknosis, raunding and desquamation of epithelial cell.

Anahtar Kelimeler

• IBV
• tracheal organ cultures
• histopathology

Kaynakça

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