Biyolojik Maddelerin Kurutularak Saklanması: Liyofilizasyon

Yıl 2015, Cilt: 26 Sayı: 1, 35 - 40, 15.06.2015

Züleyha Ergün

https://doi.org/10.35864/evmd.513369

Cited By: 1

Öz

Organik maddelerden suyun uzaklaştırılması sürecini tanımlayan liyofilizasyon, günümüzde tüm dünyada gerek sağlık endüstrisinde ve gerekse gıda endüstrisinde çok fazla kullanım alanı bulan bir tekniktir. Bu teknikte azaltılmış basınç (vakum) altında, dondurulmuş haldeki solüsyonlardan suyun uzaklaştırılması ile biyolojik maddeler ve gıdalar, bozulma meydana gelmeden uzun süre saklanabilmektedir. Liyofilizasyonun, uzun bir süreç olması, sıcaklık ve basıncın içinde bulunduğu hassas dengeler üzerine kurulmuş olması gibi dezavantajları bulunmasına rağmen halen dünyada sıklıkla kullanılan bir yöntemdir. Bu teknik, aslen eski bir yöntem olmasına karşın biyolojik ve organik maddelerin saklanmasına ilişkin daha etkin bir teknik geliştirilemediğinden günümüzde tüm dünyada halen etkinliğini ve önemini korumaktadır. Bununla birlikte prensipte aynı olmakla birlikte liyofilizasyon teknolojisi sürekli geliştirilmektedir.

Anahtar Kelimeler

Liyofilizasyon, liyofilizasyon basamakları, liyofilizasyon dezavantaj/avantajı, liyofilizasyon mekanizması, liyofilizasyon metotları

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