Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2024, Cilt: 49 Sayı: 3, 525 - 538, 23.10.2024
https://doi.org/10.55262/fabadeczacilik.1511498

Öz

Kaynakça

  • Zongo, C., Savadogo, A., Ouattara, L., Bassole, I. H. N., Ouattara, C. A. T., Ouattara, A. S., . . . TraoreI, A. S. (2010). Polyphenols content, antioxidant and antimicrobial activities of Ampelocissus grantii (Baker) Planch.(Vitaceae): a medicinal plant from Burkina Faso. International Journal of Pharmacology, 6(6), 880–887. https://doi: 10.3923/ijp.2010.880.887

Evaluation of Antioxidant, Cytotoxic Effects and Phytochemical Profiles of Galls Caused by Eriophyidae mite in Juglans regia Leaves

Yıl 2024, Cilt: 49 Sayı: 3, 525 - 538, 23.10.2024
https://doi.org/10.55262/fabadeczacilik.1511498

Öz

This research presents the first study findings on the phytochemical contents and anticancer and antioxidant activities of galls caused by Eriophyidae mites on the leaves of Juglans regia L. Gall extracts collected from different localities in Turkey and prepared with solvents of different polarity were investigated for both antioxidant and cytotoxic activity. Cytotoxic activity studies showed that MCF-7 cancer cells were more sensitive to WLAA extract at a concentration of 100 µg/mL compared to healthy HUVEC cell lines. LC-QTOF-MS analysis results showed that all extracts contain chlorogenic acid, quercetin 4'-glucoside/quercetin 3-galactoside, quercetin 7-xyloside/quercetin 3-arabinoside, quercetin 7-rhamnoside, kaempferol 3-xyloside/kaempferol 3-O-arabinoside, and kaempferol derivatives. It was concluded that polyphenolic extracts obtained from galls formed in J. regia leaves can be considered as a new potential natural source for drug development studies due to their antioxidant and cytotoxic effects.

Kaynakça

  • Zongo, C., Savadogo, A., Ouattara, L., Bassole, I. H. N., Ouattara, C. A. T., Ouattara, A. S., . . . TraoreI, A. S. (2010). Polyphenols content, antioxidant and antimicrobial activities of Ampelocissus grantii (Baker) Planch.(Vitaceae): a medicinal plant from Burkina Faso. International Journal of Pharmacology, 6(6), 880–887. https://doi: 10.3923/ijp.2010.880.887
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Farmakognozi
Bölüm Araştırma Makalesi
Yazarlar

Semih Bulut 0000-0002-4098-0221

Burçin Özüpek 0000-0003-2159-9860

Sultan Pekacar 0000-0002-7782-9832

Aysun Özdemir 0000-0003-0311-0507

Didem Deliorman Orhan 0000-0003-3916-4048

Yayımlanma Tarihi 23 Ekim 2024
Gönderilme Tarihi 6 Temmuz 2024
Kabul Tarihi 3 Ekim 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 49 Sayı: 3

Kaynak Göster

APA Bulut, S., Özüpek, B., Pekacar, S., Özdemir, A., vd. (2024). Evaluation of Antioxidant, Cytotoxic Effects and Phytochemical Profiles of Galls Caused by Eriophyidae mite in Juglans regia Leaves. Fabad Journal of Pharmaceutical Sciences, 49(3), 525-538. https://doi.org/10.55262/fabadeczacilik.1511498