MOLEKÜLER BİYOLOJİ AÇISINDAN İNSANDA İNCE AYAR ARGÜMANI

Yıl 2023, , 347 - 368, 27.11.2023

Selcen Çelik Uzuner

https://doi.org/10.53844/flsf.1301688

Öz

İnce ayar argümanı, yaşam için en uygun şartları sağlayan bir evrenin varlığını açıklamak için fizik ve felsefenin ilgisini çekmiştir; ancak, özellikle moleküler biyoloji olmak üzere biyolojik bilimlerde kapsamlı bir şekilde tartışılmamıştır. Moleküler biyoloji, rasgele olaylara ve sınırlı yasalara sahip olduğu için fizik ve matematikten farklıdır. Bu bağlamda, biyolojik bilimler, sabitler ve yasalar için yeniden gözden geçirilmelidir. Oysa hücrelerdeki sistematik olaylar, moleküler biyolojide ince ayar argümanının tartışılabilme imkanını da beraberinde getirmektedir. Hücreler sistematik olarak molekül, gen ve genom düzeylerinde birçok moleküler mekanizmayı gerçekleştirir. Bu çalışma, hücrelerde ve genomdaki ince ayarların varlığını tartışmayı hedeflemektedir. Bu çalışma kapsamında molekül, gen, genom ve/veya organizma seviyelerinde meydana gelen 1) konum, 2) etkileşim, 3) miktar ve 4) zaman olmak üzere dört grup ince ayar parametresi önerilmektedir. Bu ince ayar parametreleri birbiriyle ilişkilendirilerek hayatı birlikte yönetmektedir. Dolayısıyla sistematik hücresel aktiviteler, bu karmaşıklığın insanın moleküler sistemindeki ince ayar ile yönetildiğine işaret etmektedir.

Anahtar Kelimeler

İnce ayar argümanı, moleküler biyoloji, felsefe, rastgelelik, akıllı tasarım

FINE-TUNING ARGUMENT FROM THE PERSPECTIVE OF MOLECULAR BIOLOGY IN HUMAN

Öz

Fine tuning argument has been of interest in physics and philosophy to answer the existence of the universe which is best fit for life; however, it has not been extensively applied to biological sciences in particular molecular biology. Molecular biology is different from physics and mathematics as it has stochastic events and limited laws. Biological sciences should be revisited for constants and laws. Though, the systematic events in the cells bring on the possibility of fine-tuning in molecular biology. Cells systematically perform many molecular mechanisms at molecule, gene and genome levels. This work focuses on the fine-tuning argument in the cells and the genome, and suggests four fine-tuning parameters 1) position, 2) interaction, 3) amount, and 4) time which occur at molecule, gene, genome and/or organism levels. These fine-tuning parameters are associated with each other and manage life together. Systematic cellular activities suggest that this complexity is managed by fine-tuning in human’s molecular system.

Anahtar Kelimeler

Fine tuning argument, molecular biology, philosophy, randomness, intelligent design

Kaynakça

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