Prevalence and types of developmental enamel defects in primary teeth of preterm children

Yıl 2020, , 13 - 17, 01.01.2020

İlkay Peker , Umut Pamukçu , Çağdaş Çınar , Mesut Odabaş , İdil Kızılırmak Tuğçe Talay Bülent Altunkaynak , Zühre Akarslan

https://doi.org/10.17214/gaziaot.562971

Öz

Objective: To
compare the prevalence and developmental enamel defect (DED) types in primary
teeth in preterm-born with term-born children.

Materials and
Method: This study included 150
children. The children were divided into two groups as premature (n=75, mean
age=7.1±2.9
year) and term-born (control group,
n=75, mean age=7.6±2.5
year). In the clinical examination, DED
and the defect type were recorded according to the modified DED index. Data
were analyzed using Pearson's Chi-Square, Fisher's exact and t-tests.

Results:
DED was observed 34/75 (45.3%) in the
premature group and 15/75 (20%) in the control group (p<0.01). DED was detected
in 193 teeth. The prevalence of DED was higher in the premature group (n=148,
76.7%) than in the control group (n=45, 23.3%). DED was most commonly found in
the maxillary incisors of the premature group and the maxillary molars of the
control group. The DED types were found to be enamel opacity (demarcated
white/cream opacity, demarcated yellow/brown opacity, diffuse opacity as lines,
and diffuse patchy opacity) in 88.5% (n=131) teeth and enamel hypoplasia in
11.5% (n=17) teeth of the premature group, and as enamel hypoplasia in all
teeth of the control group (n=45, 100%). Significantly more teeth in the
premature group than in the control group exhibited demarcated white/cream
opacity and demarcated yellow/brown opacity at the enamel (p<0.01).

Conclusion: This study showed that premature children had more
DED than term-born children, and these defects were mostly observed in the
maxillary incisors and observed as demarcated opacities.

Anahtar Kelimeler

Deciduous teeth, dental enamel, infant, premature

Prematüre doğmuş çocukların süt dişlerindeki gelişimsel mine defektlerinin görülme sıklığı ve tipleri

Öz

Amaç: Prematüre doğan çocukların süt
dişlerinde izlenen gelişimsel mine defektlerinin (GMD) görülme sıklığı ve
tiplerinin, normal doğum yaşında dünyaya gelmiş çocuklar ile
karşılaştırılmasıdır.

Gereç ve Yöntem: Araştırmaya
150 çocuk dahil edildi. Çocuklar, prematüre doğan (n=75, yaş=7.1±2.9 yıl) ve normal doğum yaşında doğmuş çocuklar (kontrol grubu, n=75, yaş=7.6±2.5 yıl) olmak üzere iki gruba ayrıldı. Klinik muayenede her iki grupta GMD olup
olmadığı belirlendi. GMD belirlenen dişler, Modifiye GMD İndeksindeki tiplere
göre sınıflandırıldı. Veriler Pearson ki-kare, Fisher'in kesin testi ve t-testi
kullanılarak istatistiksel olarak analiz edildi.

Bulgular: Prematüre grubunda 34/75 (%45.3) çocukta, kontrol grubunda ise 15/75 (%20)
çocukta GMD saptandı (p<0.01). Çalışmada toplam 193 dişte GMD tespit edildi.
Prematüre grupta GMD görülme sıklığı (n=148, %76.7), kontrol grubundan (n=45,
%23.3) daha fazlaydı. En fazla GMD, prematüre grubunda maksiller keser dişlerde,
kontrol grubunda ise maksiller molar dişlerde izlendi. Prematüre grubundaki GMD’nin
%88.5’i (n=131) mine opasitesi (sınırlı beyaz/krem rengi opasite,
sınırlı sarı/kahverengi opasite, diffüz çizgi şeklinde opasite ve diffüz yamalı
opasite) ve %11.5’i
(n=17) mine hipoplazisi tipindeyken; kontrol grubundaki dişlerin tümünde mine
opasitesi (n=45, %100) şeklindeydi. Prematüre grubunda, minede sınırlı beyaz/krem rengi opasite ve
sınırlı sarı/kahverengi opasite bulunan
diş sayısı kontrol grubuna göre istatistiksel olarak anlamlı düzeyde fazla
bulundu (p<0.01).

Sonuç: Çalışmanın sonuçları, prematüre
doğan çocukların süt dişlerinde normal
doğum yaşında dünyaya gelmiş çocuklardan daha fazla GMD görüldüğünü, bu
defektlerin çoğunlukla maksiller kesici dişlerde ve minede sınırlı opasite şeklinde
ortaya çıktığını gösterdi.

Anahtar Kelimeler

Bebek, diş minesi, prematür, süt dişleri

Kaynakça

• Prokocimer T, Amir E, Blumer S, Peretz B. Birth-weight, pregnancy term, pre-natal and natal complications related to child’s dental anomalies. J Clin Pediatr Dent 2015;39:371-6.
• Machado Junior LC, Passini Junior R, Rodriges Machado Rosa I. Late prematurity: a systematic review. J Pediatr (Rio J) 2014;90:221-31.
• Seow WK, Brown J, Tudehope D, O'callaghan M. Developmental defects in the primary dentition of low birth-weight infants: adverse effects of laryngoscopy and prolonged endotracheal intubation. Pediatr Dent 1984;6:28-31.
• Usher RH. The special problems of the premature infant. In: Avery GB, editors. Neonatology: Pathophysiology and Management of the Newborn. 2nd ed. Philadelphia: JB Lippincott; 1987. p. 230-61.
• Pearson G, Shann F, Barry P, Vyas J, Thomas D, Powell C, et al. Should paediatric intensive care be centralised? Trent versus Victoria. Lancet 1997;349:1213-7.
• Slattery MM, Morrison JJ. Preterm delivery. Lancet 2002;360:1489-97.
• Seow WK. Effect of preterm birth on oral growth and development. Aust Dent J 1997;42: 85-91.
• Seow WK. Clinical diagnosis of enamel defects: pitfalls and practical guidelines. Int Dent J 1997;47:173-82.
• Lunt RC, Law DB. A review of the chronology of calcification of deciduous teeth. JADA 1974;89:599-606.
• Salanitri S, Seow W. Developmental enamel defects in the primary dentition:aetiology and clinical management. Aust Dent J 2013;58:133-40.
• Kreshover SJ, Clough OW. Prenatal influences on tooth development:II.Artificially induced fever in rats. J Dent Res 1953;32:565-77.
• Ford D, Seow WK, Kazoullis S, Holcombe T, Newman B. A controlled study of risk factors for enamel hypoplasia in the permanent dentition. Pediatr Dent 2009;31:382-8.
• Seow WK. Enamel hypoplasia in the primary dentition:a review. ASDC J Dent Child 1991;58:441-52.
• Owen L. The effects of administering tetracyclines to young dogs with particular reference to localization of the drugs in the teeth. Arch Oral Biol 1963;8:715-28.
• Hong L, Levy SM, Warren JJ, Dawson DV, Bergus GR, Wefel JS. Association of amoxicillin use during early childhood with developmental tooth enamel defects. Arch Pediatr Adolesc Med 2005;159:943-8.
• Seow WK, Humphrys C, Tudehope DI. Increased prevalence of developmental dental defects in low birth-weight, prematurely born children: a controlled study. Pediatr Dent 1987;9:221-5.
• Takaoka LA, Goulart AL, Kopelman BI, Weiler RM. Enamel defects in the complete primary dentition of children born at term and preterm. Pediatr Dent 2011;33:171-6.
• Aine L, Backström M, Mäki R, Kuusela AL, Koivisto AM, Ikonen RS, et al. Enamel defects in primary and permanent teeth of children born prematurely. J Oral Pathol Med 2000;29:403-9.
• Clarkson J, O'mullane D. A modified DDE Index for use in epidemiological studies of enamel defects. J Dent Res 1989;68:445-50.
• Barlak P, Koruyucu M, Bayram M, Nurkoviç A, Seymen F. Süt Dişlerinde Görülen Gelişimsel Mine Defektlerinin Değerlendirilmesi. Türkiye Klinikleri J Dental Sci 2013;19:129-37.
• Correa Faria P, Martins Junior PA, Vieria Andrade RG, Oliveia Ferreira F, Marques LS, Ramos Jorge ML. Developmental defects of enamel in primary teeth: prevalence and associated factors. Int J Paediatr Dent 2013;23:173-9.
• Wagner Y. Developmental defects of enamel in primary teeth-findings of a regional German birth cohort study. BMC Oral Health 2017;17:10.
• Gravina D, Cruvinel V, Azevedo T, Toledo O, Bezerra A. Enamel defects in the primary dentition of preterm and full term children. J Clin Pediatr Dent 2013;37:391-5.
• Cortines AAO, Corrêa-Faria P, Paulsson L, Costa PS, Costa LR. Developmental defects of enamel in the deciduous incisors of infants born preterm: Prospective cohort. Oral Dis 2019;25:543-9.
• Jacobsen PE, Haubek D, Henriksen TB, Østergaard JR, Poulsen S. Developmental enamel defects in children born preterm: a systematic review. Eur J Oral Sci 2014;122:7-14.
• Cruvinel VR, Gravina DB, Azevedo TD, Rezende CS, Bezerra AC, Toledo OA. Prevalence of enamel defects and associated risk factors in both dentitions in preterm and full term born children. J Appl Oral Sci 2012;20:310-7.
• Rythén M, Niklasson A, Hellström A, Hakeberg M, Robertson A. Risk indicators for poor oral health in adolescents born extremely preterm. Swed Dent J 2012;36:115-24.
• Cruvinel VR, Gravina DB, Azevedo TD, Bezerra AC, Toledo OA. Prevalence of dental caries and caries-related risk factors in premature and term children. Braz Oral Res 2010; 24: 329-35.
• Hong L, Levy S, Warren J, Broffitt B. Association between enamel hypoplasia and dental caries in primary second molars: a cohort study. Caries Res 2009;43:345-53.
• Kazoullis S, Seow WK, Holcombe T, Newman B, Ford D. Common dental conditions associated with dental erosion in schoolchildren in Australia. Pediatr Dent 2007;29:33-9.
• Seow WK, Ford D, Kazoullis S, Newman B, Holcombe T. Comparison of enamel defects in the primary and permanent dentitions of children from a low-fluoride District in Australia. Pediatr Dent 2011;33:207-12.
• Seow WK. Oral complications of premature birth. Aust Dent J 1986;31:23-9.
• Fadavi S, Punwani I, Vidyasagar D. Prevalence of dental caries in prematurely-born children. J Clin Pediatr Dent 1993;17:163-5.
• Li Y, Navia JM, Bian JY. Prevalence and distribution of developmental enamel defects in primary dentition of Chinese children 3–5 years old. Community Dent Oral Epidemiol 1995;23:72-9.
• Costa FS, Silveira ER, Pinto GS, Nascimento GG, Thomson WM, Demarco FF. Developmental defects of enamel and dental caries in the primary dentition: A systematic review and meta-analysis. J Dent 2017;60:1-7.