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Effect of CPAP Therapy on Clinical Periodontal Status of Patients with Obstructive Sleep Apnea Syndrome: 6-year Follow-up

Yıl 2020, , 42 - 47, 01.05.2020
https://doi.org/10.17214/gaziaot.630740

Öz

Objective: The aim of this study is to evaluate the possible effect of the continuous positive airway pressure (CPAP) device on the periodontal status in obstructive sleep apnea syndrome (OSAS) patients.


Materials and Method: Comprehensive clinical periodontal examination was repeated 6 years after the treatment was started in 11 patients (3 moderate, 8 severe OSAS) who were diagnosed with OSAS and using CPAP device regularly. Probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP) and plaque index (PI) were recorded and compared with the baseline data.


Results: There was no significant difference between the moderate and severe OSAS groups in terms of CAL, PI measurements between the baseline and the 6th year after the treatment (p>0.05). Baseline, 6th year PD and the 6th year BOP values were higher in the moderate OSAS group (p = 0.024, p = 0.030 and p=0.014, respectively). No significant difference was found in the number of teeth present between the baseline and the 6th year in either of the groups or the whole population (p>0.05). When the clinical periodontal measurements were compared between the baseline and the 6th year in smokers and non-smokers, the results were found to be similar (p>0.05).


Conclusion: Within the limits of the present study, it can be concluded that long-term OSAS treatment with CPAP device does not have a significant effect on the clinical periodontal status.

Kaynakça

  • Haffajee AD, Socransky SS. Microbial etiological agents of destructive periodontal diseases. Periodontol 2000 2000;5:78-111.
  • Albandar JM, Brunelle JA, Kingman A. Destructive periodontal disease in adults 30 years of age and older in the United States, 1988–1994. J Periodontol 1999;70:13-29.
  • American Academy of Sleep Medicine. International Classification of Sleep Disorders: Diagnostic and Coding Manual, 2nd ed. Westchester, IL: American Academy of Sleep Medicine 2005;52-58.
  • Dieltjens M, Vanderveken O. Oral appliances in obstructive sleep apnea. Healthcare (Basel). 2019;7:141.
  • Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-1235.
  • Bradley TD, Floras JS. Obstructive sleep apnea and its cardiovascular consequences. Lancet 2009;373:82-93.
  • Selim B, Won C, Yaggi HK. Cardiovascular consequencesof sleep apnea. Clin Chest Med 2010;31:203-220.
  • Filoche SK, Cornford E, Gaudie W, Wong M, Heasman P, Thomson WM. Smoking, chronic periodontitis and smoking cessation support: Reviewing the role of dental professionals. N Z Dent J 2010;106:74-77.
  • Arbes SJ Jr, Agústsdóttir H, Slade GD. Environmental tobacco smoke and periodontal disease in the United States. Am J Public Health 2001;91:253-257.
  • Timmerman MF, van der Weijden GA. Risk factors for periodontitis. Int J Dent Hyg 2006;4:2-7.
  • Young T, Skatrud J, Peppard PE. Risk factors for obstructive sleep apnea in adults. JAMA 2004;291:2013-2016.
  • Gunaratnam K, Taylor B, Curtis B, Cistulli P. Obstructive sleep apnea and periodontitis: A novel association? Sleep Breath 2009;13:233-239.
  • Seo WH, Cho ER, Thomas RJ, et al. The association between periodontitis and obstructive sleep apnea: A preliminary study. J Periodontal Res 2013;48:500-506.
  • Sleep-related breathing disorders in adults: Recommendations for syndrome definitionand measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22:667-668.
  • Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005;365:1046-1053.
  • Marsh PD. Dental plaque as a biofilm and a microbial community-implications for health and disease. BMC Oral Health 2006;6:14.
  • Mahale SA, Kalasva PK, Shinde SV. Hyperbaric oxygen therapy in periodontal diseases. J Int Clin Dent Res Organ 2013;5:3-8.
  • Chowdhuri S. Continuous positive airway pressure for the treatment of sleep apnea. Otolaryngol Clin North Am 2007;40:807-827.
  • Nizam N, Başoğlu ÖK, Taşbakan MS, Nalbantsoy A, Buduneli N. Salivary cytokines and the association between obstructive sleep apnea syndrome and periodontal disease. J Periodontol 2014;85:251-258.
  • Erley KJ, Swiec GD, Herold R, Bisch FC, Peacock ME. Gingival recession treatment with connective tissue grafts in smoker and non-smokers. J Periodontol 2006; 77:1148-1155.
  • Quigley GA, Hein JW. Comparative cleansing efficiency of manual and power brushing. J Am Dent Assoc 1962;65:26-29.
  • Popova C, Dosseva-Panova V, Panov V. Microbiology of periodontal diseases. A review. Biotechnology & Biotechnological Equipment 2013;27:3754-3759.
  • Latorre C, Escobar F, Velosa J, Rubiano D, Hidalgo-Martinez P, Otero L. Association between obstructive sleep apnea and comorbidities with periodontal disease in adults. J Indian Soc Periodontol 2018;22:215-220.
  • Al-Jewair TS, Al-Jasser R, Almas K. Periodontitis and obstructive sleep apnea’s bidirectional relationship: a systematic review and meta-analysis. Sleep Breath 2015;19:1111-1120.
  • Nizam N, Basoglu OK, Tasbakan MS, Holthöfer A, Tervahartiala T, Sorsa T, Buduneli N. Do salivary and serum collagenases have a role in an association between obstructive sleep apneasyndrome and periodontal disease? A preliminary case–control study. Arch Oral Biol 2015;60:134-143.
  • Nizam N, Basoglu OK, Tasbakan MS, Lappin DF, & Buduneli N. Is there an association between obstructive sleep apnea syndrome and periodontal inflammation? Clin Oral Invest 2015;20:659-668.
  • Loke W, Girvan T, Ingmundson P, Verrett R, Schoolfield J, Mealey BL. Investigating the association between obstructive sleep apnea and periodontitis. J Periodontol 2015;86:232-243.
  • Vlachantoni IT, Dikaiakou E, Antonopoulos CN, Stefanadis C, Daskalopoulou SS, Petridou ET. Effects of continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea in arterial stiffness: a meta-analysis. Sleep Med Rev 2013;17:19-28.
  • Liu HW, Chen YJ, Lai YC, Huang CY, Huang YL, Lin MT, et al. Combining MAD and CPAP as an effective strategy for treating patients with severe sleep apnea intolerant to high-pressure PAP and unresponsive to MAD. PLoS ONE 2017;12:e0187032.
  • Suzuki S, Kojima Y, Takayanagi A, Yoshino K, Ishizuka Y, Satou R, et al. Relationship between obstructive sleep apnea and self-assessed oral health status: An internet survey. Bull Tokyo Dent Coll 2016;57:175-181.
  • Broström A, Årestedt KF, Strömberg A, Ulander M, Svanborg E. The side-effects to CPAP treatment inventory: the development and initial validation of a new tool for the measurement of side effects to CPAP treatment. J Sleep Res 2010;19:603-661.
  • Venema JA, Stellingsma C, Doff MH, Hoekema A. Dental side effects of long-term obstructive sleep apnea therapy: a comparison of three therapeutic modalities. Journal of Dental Sleep Medicine. 2018;5:39-46.
  • Pliska BT, Almeida FR. Tooth movement associated with CPAP therapy. J Clin Sleep Med. 2018;14:701-702.
  • Carra MC, Thomas F, Schmitt A. et al. Oral health in patients treated by positive airway pressure for obstructive sleep apnea: a population-based case-control study. Sleep Breath 2016;20:405.

Obstrüktif uyku apne sendromu olan hastalarda CPAP tedavisinin klinik periodontal duruma etkisi: Altı yıllık takip

Yıl 2020, , 42 - 47, 01.05.2020
https://doi.org/10.17214/gaziaot.630740

Öz

Amaç: Bu çalışmanın amacı, obstrüktif uyku apne sendromu (OUAS) hastalarında sürekli pozitif havayolu basıncı (CPAP) tedavisinin, klinik periodontal durum üzerine olası etkilerini değerlendirmektir.



Gereç ve Yöntem: OUAS tanısı konmuş olan ve düzenli CPAP cihazı kullanan toplam 11 hastada (3 hasta orta, 8 hasta ağır OUAS) tedavi başlandıktan 6 yıl sonra kapsamlı klinik periodontal muayene tekrarlandı. Tüm ağız ortalama sondalama derinliği (SD), klinik ataşman seviyesi (KAS), sondalamada kanama indeksi (SKİ) ve plak indeksi (Pİ) değerleri kaydedilerek başlangıç verileri ile karşılaştırıldı.



Bulgular: Orta ve ağır OUAS grupları arasında KAS, PI ölçümlerinde başlangıç ve tedavi sonrası 6. yıl verileri arasında anlamlı fark bulunmadı (p>0.05). Başlangıç, 6. yıl SD ve 6. yıl SKİ değerleri orta OUAS grubunda daha yüksek bulundu (sırasıyla p=0.024, p=0.030 ve p=0.014). Diş sayılarına bakıldığında her iki grupta ve tüm hastalarda başlangıç ve 6. yıl değerleri arasında anlamlı fark bulunmadı (p>0.05). Sigara içen ve içmeyen hastalarda başlangıç ve 6. yıl klinik periodontal ölçümleri karşılaştırdığımızda sonuçların benzer olduğu gözlendi (p>0.05).



Sonuç: Çalışmamızın sınırları içinde, CPAP cihazı ile yapılan uzun dönem OUAS tedavisinin klinik periodontal durum üzerine anlamlı etki göstermediği söylenebilir.

Kaynakça

  • Haffajee AD, Socransky SS. Microbial etiological agents of destructive periodontal diseases. Periodontol 2000 2000;5:78-111.
  • Albandar JM, Brunelle JA, Kingman A. Destructive periodontal disease in adults 30 years of age and older in the United States, 1988–1994. J Periodontol 1999;70:13-29.
  • American Academy of Sleep Medicine. International Classification of Sleep Disorders: Diagnostic and Coding Manual, 2nd ed. Westchester, IL: American Academy of Sleep Medicine 2005;52-58.
  • Dieltjens M, Vanderveken O. Oral appliances in obstructive sleep apnea. Healthcare (Basel). 2019;7:141.
  • Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-1235.
  • Bradley TD, Floras JS. Obstructive sleep apnea and its cardiovascular consequences. Lancet 2009;373:82-93.
  • Selim B, Won C, Yaggi HK. Cardiovascular consequencesof sleep apnea. Clin Chest Med 2010;31:203-220.
  • Filoche SK, Cornford E, Gaudie W, Wong M, Heasman P, Thomson WM. Smoking, chronic periodontitis and smoking cessation support: Reviewing the role of dental professionals. N Z Dent J 2010;106:74-77.
  • Arbes SJ Jr, Agústsdóttir H, Slade GD. Environmental tobacco smoke and periodontal disease in the United States. Am J Public Health 2001;91:253-257.
  • Timmerman MF, van der Weijden GA. Risk factors for periodontitis. Int J Dent Hyg 2006;4:2-7.
  • Young T, Skatrud J, Peppard PE. Risk factors for obstructive sleep apnea in adults. JAMA 2004;291:2013-2016.
  • Gunaratnam K, Taylor B, Curtis B, Cistulli P. Obstructive sleep apnea and periodontitis: A novel association? Sleep Breath 2009;13:233-239.
  • Seo WH, Cho ER, Thomas RJ, et al. The association between periodontitis and obstructive sleep apnea: A preliminary study. J Periodontal Res 2013;48:500-506.
  • Sleep-related breathing disorders in adults: Recommendations for syndrome definitionand measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22:667-668.
  • Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005;365:1046-1053.
  • Marsh PD. Dental plaque as a biofilm and a microbial community-implications for health and disease. BMC Oral Health 2006;6:14.
  • Mahale SA, Kalasva PK, Shinde SV. Hyperbaric oxygen therapy in periodontal diseases. J Int Clin Dent Res Organ 2013;5:3-8.
  • Chowdhuri S. Continuous positive airway pressure for the treatment of sleep apnea. Otolaryngol Clin North Am 2007;40:807-827.
  • Nizam N, Başoğlu ÖK, Taşbakan MS, Nalbantsoy A, Buduneli N. Salivary cytokines and the association between obstructive sleep apnea syndrome and periodontal disease. J Periodontol 2014;85:251-258.
  • Erley KJ, Swiec GD, Herold R, Bisch FC, Peacock ME. Gingival recession treatment with connective tissue grafts in smoker and non-smokers. J Periodontol 2006; 77:1148-1155.
  • Quigley GA, Hein JW. Comparative cleansing efficiency of manual and power brushing. J Am Dent Assoc 1962;65:26-29.
  • Popova C, Dosseva-Panova V, Panov V. Microbiology of periodontal diseases. A review. Biotechnology & Biotechnological Equipment 2013;27:3754-3759.
  • Latorre C, Escobar F, Velosa J, Rubiano D, Hidalgo-Martinez P, Otero L. Association between obstructive sleep apnea and comorbidities with periodontal disease in adults. J Indian Soc Periodontol 2018;22:215-220.
  • Al-Jewair TS, Al-Jasser R, Almas K. Periodontitis and obstructive sleep apnea’s bidirectional relationship: a systematic review and meta-analysis. Sleep Breath 2015;19:1111-1120.
  • Nizam N, Basoglu OK, Tasbakan MS, Holthöfer A, Tervahartiala T, Sorsa T, Buduneli N. Do salivary and serum collagenases have a role in an association between obstructive sleep apneasyndrome and periodontal disease? A preliminary case–control study. Arch Oral Biol 2015;60:134-143.
  • Nizam N, Basoglu OK, Tasbakan MS, Lappin DF, & Buduneli N. Is there an association between obstructive sleep apnea syndrome and periodontal inflammation? Clin Oral Invest 2015;20:659-668.
  • Loke W, Girvan T, Ingmundson P, Verrett R, Schoolfield J, Mealey BL. Investigating the association between obstructive sleep apnea and periodontitis. J Periodontol 2015;86:232-243.
  • Vlachantoni IT, Dikaiakou E, Antonopoulos CN, Stefanadis C, Daskalopoulou SS, Petridou ET. Effects of continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea in arterial stiffness: a meta-analysis. Sleep Med Rev 2013;17:19-28.
  • Liu HW, Chen YJ, Lai YC, Huang CY, Huang YL, Lin MT, et al. Combining MAD and CPAP as an effective strategy for treating patients with severe sleep apnea intolerant to high-pressure PAP and unresponsive to MAD. PLoS ONE 2017;12:e0187032.
  • Suzuki S, Kojima Y, Takayanagi A, Yoshino K, Ishizuka Y, Satou R, et al. Relationship between obstructive sleep apnea and self-assessed oral health status: An internet survey. Bull Tokyo Dent Coll 2016;57:175-181.
  • Broström A, Årestedt KF, Strömberg A, Ulander M, Svanborg E. The side-effects to CPAP treatment inventory: the development and initial validation of a new tool for the measurement of side effects to CPAP treatment. J Sleep Res 2010;19:603-661.
  • Venema JA, Stellingsma C, Doff MH, Hoekema A. Dental side effects of long-term obstructive sleep apnea therapy: a comparison of three therapeutic modalities. Journal of Dental Sleep Medicine. 2018;5:39-46.
  • Pliska BT, Almeida FR. Tooth movement associated with CPAP therapy. J Clin Sleep Med. 2018;14:701-702.
  • Carra MC, Thomas F, Schmitt A. et al. Oral health in patients treated by positive airway pressure for obstructive sleep apnea: a population-based case-control study. Sleep Breath 2016;20:405.
Toplam 34 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Diş Hekimliği
Bölüm Özgün Araştırma Makalesi
Yazarlar

Burcu Kanmaz 0000-0001-9100-8398

Nejat Nizam Bu kişi benim

Özen Kaçmaz Başoğlu

M. Sezai Taşbakan

Nurcan Buduneli Bu kişi benim

Yayımlanma Tarihi 1 Mayıs 2020
Yayımlandığı Sayı Yıl 2020

Kaynak Göster

APA Kanmaz, B., Nizam, N., Kaçmaz Başoğlu, Ö., Taşbakan, M. S., vd. (2020). Obstrüktif uyku apne sendromu olan hastalarda CPAP tedavisinin klinik periodontal duruma etkisi: Altı yıllık takip. Acta Odontologica Turcica, 37(2), 42-47. https://doi.org/10.17214/gaziaot.630740
AMA Kanmaz B, Nizam N, Kaçmaz Başoğlu Ö, Taşbakan MS, Buduneli N. Obstrüktif uyku apne sendromu olan hastalarda CPAP tedavisinin klinik periodontal duruma etkisi: Altı yıllık takip. Acta Odontol Turc. Mayıs 2020;37(2):42-47. doi:10.17214/gaziaot.630740
Chicago Kanmaz, Burcu, Nejat Nizam, Özen Kaçmaz Başoğlu, M. Sezai Taşbakan, ve Nurcan Buduneli. “Obstrüktif Uyku Apne Sendromu Olan Hastalarda CPAP Tedavisinin Klinik Periodontal Duruma Etkisi: Altı yıllık Takip”. Acta Odontologica Turcica 37, sy. 2 (Mayıs 2020): 42-47. https://doi.org/10.17214/gaziaot.630740.
EndNote Kanmaz B, Nizam N, Kaçmaz Başoğlu Ö, Taşbakan MS, Buduneli N (01 Mayıs 2020) Obstrüktif uyku apne sendromu olan hastalarda CPAP tedavisinin klinik periodontal duruma etkisi: Altı yıllık takip. Acta Odontologica Turcica 37 2 42–47.
IEEE B. Kanmaz, N. Nizam, Ö. Kaçmaz Başoğlu, M. S. Taşbakan, ve N. Buduneli, “Obstrüktif uyku apne sendromu olan hastalarda CPAP tedavisinin klinik periodontal duruma etkisi: Altı yıllık takip”, Acta Odontol Turc, c. 37, sy. 2, ss. 42–47, 2020, doi: 10.17214/gaziaot.630740.
ISNAD Kanmaz, Burcu vd. “Obstrüktif Uyku Apne Sendromu Olan Hastalarda CPAP Tedavisinin Klinik Periodontal Duruma Etkisi: Altı yıllık Takip”. Acta Odontologica Turcica 37/2 (Mayıs 2020), 42-47. https://doi.org/10.17214/gaziaot.630740.
JAMA Kanmaz B, Nizam N, Kaçmaz Başoğlu Ö, Taşbakan MS, Buduneli N. Obstrüktif uyku apne sendromu olan hastalarda CPAP tedavisinin klinik periodontal duruma etkisi: Altı yıllık takip. Acta Odontol Turc. 2020;37:42–47.
MLA Kanmaz, Burcu vd. “Obstrüktif Uyku Apne Sendromu Olan Hastalarda CPAP Tedavisinin Klinik Periodontal Duruma Etkisi: Altı yıllık Takip”. Acta Odontologica Turcica, c. 37, sy. 2, 2020, ss. 42-47, doi:10.17214/gaziaot.630740.
Vancouver Kanmaz B, Nizam N, Kaçmaz Başoğlu Ö, Taşbakan MS, Buduneli N. Obstrüktif uyku apne sendromu olan hastalarda CPAP tedavisinin klinik periodontal duruma etkisi: Altı yıllık takip. Acta Odontol Turc. 2020;37(2):42-7.