Antimicrobial effect of propolis against oral microorganisms

Yıl 2015, , 36 - 41, 09.02.2015

Ülkü Özan , Fatih Özan Kürşat Er

https://doi.org/10.17214/aot.43682

Cited By: 1

Öz

Natural products have been used for thousands of years in folk medicine for several purposes. Among them, propolis has attracted increased interest due to its antimicrobial activity against a wide range of pathogenic microorganisms. The content of propolis presents diversity depending on the season it is collected and on the native vegetation, the flora, the bees derive the material from. All propolis samples from different geographical locations, in spite of the variations between chemical compositions, exhibit significant antimicrobial activity. The pharmacologically active molecules in propolis are flavonoids and phenolic acids and their esters. According to the latest studies, propolis exhibits inhibitory activity against oral pathogenic microorganisms. Considering development of resistance by microorganisms against antimicrobials and transfer of this trait between bacteria and considering other side effects of the antimicrobials, search for new therapies against the diseases of the oral cavity becomes of great importance.

Anahtar Kelimeler

Antimicrobial Agents, Bacteria, Dental Caries, Fungus, Oral Health, Periodontitis, Propolis, Virus

Oral mikroorganizmalara karşı propolisin antimikrobiyal etkinliği

Öz

Çeşitli amaçlarla halk hekimliğinde binlerce yıldır doğal ürünler kullanılmaktadır. Bu ürünlerin arasında, patojenik mikroorganizmalar üzerine antimikrobiyal aktivitesi çok iyi olan propolis, son zamanlarda çok fazla ilgi çekmektedir. Propolis içeriği, arının gezdiği alanlardaki floraya ve toplandığı zamana göre oldukça farklılık ve zenginlik göstermektedir. Kimyasal bileşimlerindeki farklılıklara rağmen, tüm propolis ürünleri belirgin biçimde antimikrobiyal etkinlik göstermektedir. Bunlar, farmakolojik olarak aktif moleküller flavonoidler, fenolik asitler ve esterler olarak sayılabilir. Son zamanlarda yapılan çalışmalardan elde edilen verilere göre propolis, ağızdaki patojenik mikroorganizmalar üzerine belirgin inhibisyon göstermektedir. Antimikrobiyal ajanlara karşı mikroorganizmaların direnç geliştirmeleri, geliştirdikleri direnç mekanizmalarını bakteriler arası ilişki ile birbirlerine aktarmaları ve diğer yan etkileri de göz önünde bulundurulduğunda ağız boşluğu hastalıklarının tedavisinde yeni tedavi yöntemleri oldukça önem arz etmektedir.

Anahtar Kelimeler

Ağız Sağlığı, Antimikrobiyal Ajanlar, Bakteri, Diş Çürükleri, Mantar, Periodontitis, Propolis, Virüs

Kaynakça

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