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Molar incisor hypomineralization: etiology and clinical management

Yıl 2015, , 90 - 7, 21.04.2015
https://doi.org/10.17214/aot.71184

Öz

Molar incisor hypomineralisation (MIH) is a common developmental condition resulting in enamel defects in first permanent molars and permanent incisors. Its prevalance varies between 2.8% and 44%. The etiology of MIH has not been fully clarified; however it is supposed that environmental and systemic conditions may be possible reasons for this condition. Hypomineralized molars exhibit proneness to caries, and severe restorative problems are often associated with such teeth. Incisors also present demarcated enamel opacities, although enamel breakdown is uncommon. The treatment of MIH depends on the severity of the enamel defect. A six step approach to management has been suggested, comprising: risk identification, early diagnosis, remineralization and desensitization, prevention of caries and post-eruption breakdown, restoration and extraction and maintenance of oral hygiene and oral care. The purpose of this review was to inform the reader on the diagnosis and treatment of MIH.

Kaynakça

  • Weerheijm KL, Jälevik B, Alaluusua S. Molar-incisor hypomineralization. Caries Res 2001;35:390-1.
  • Weerheijm KL, Duggal M, Mejàre I, Papagiannoulis L, Koch G, Martens LC, et al. Judgement criteria for molar-incisor hypomineralisation MIH in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. Eur J Paediatr Dent 2003;4:110-3.
  • Koch G, Hallonsten AL, Ludvigsson N. Hansson BO, Hoist A, Ullbro C. Epidemiologic study of idiopatic enamel hypomineralization in permanent teeth of Sweedish children. Community Dent Oral Epidemiol 1987;15:279-85.
  • Jälevik B. Prevalence and Diagnosis of Molar-Incisor- Hypomineralisation (MIH): A systematic review. Eur Arch Paediatr Dent 2010;11:59-64.
  • Weerheijm KL. Molar incisor hypomineralisation. Eur J Paediatr Dent 2003;4:114-20.
  • Mathu-Muju K, Wright JT. Diagnosis and treatment of molar incisor hypomineralization. Compend Contin Educ Dent 2006;27:604-10.
  • Ogden AR, Pinhasi R, White WJ. Gross enamel hypoplasia in molars from subadults in a 16th-18th century London graveyard. Amer J Physic Anthropol 2007;133:957-66.
  • Willmott NS, Bryan RA, DuggalMS.Molar-incisor-hypomineralisation: a literature review. Eur Arch Paediatr Dent 2008;9:172-9.
  • Parikh DR, Ganesh M, Bhaskar V. Prevalence and characteristics of Molar Incisor Hypomineralisation (MIH) in the child population residing in Gandhinagar, Gujarat, India. Eur Arch Paediatr Dent 2012;13:21-6.
  • Balmer R, Toumba J, Godson J, Duggal M. The prevalence of molar incisor hypomineralisation in Northern England and its relationship to socioeconomic status and water fluoridation. Int J Paediatr Dent 2012;22:250-7.
  • Martínez Gómez TP, Guinot Jimeno F, Bellet Dalmau LJ, Giner Tarrida L. Prevalence of molar-incisor hypomineralisation observed using transillumination in a group of children from Barcelona (Spain). Int J Paediatr Dent 2012;22:100-9.
  • Mahoney EK, Morrison DG. Further examination of the prevalence of MIH in the Wellington region. NZ Dent J 2011;107:79-84.
  • Ghanim A, Morgan M, Mariño R, Bailey D, Manton D. Molar-incisor hypomineralisation: prevalence and defect characteristics in Iraqi children. Int J Paediatr Dent 2011;21:413-21.
  • Zawaideh FI, Al-Jundi SH, Al-Jaljoli MH. Molar incisor hypomineralisation: prevalence in Jordanian children and clinical characteristics. Eur Arch Paediatr Dent 2011;12:31-6.
  • Mahoney EK, Morrison DG. The prevalence of Molar Incisor Hypomineralisation (MIH) in Wainuiomata children. NZ Dent J 2009;105:121-7.
  • Kuscu OO, Caglar E, Aslan S, Durmusoglu E, Karademir A, Sandalli N. The prevalence of molar incisor hypomineralization (MIH) in a group of children in a highly polluted urban region and a windfarm-green energy island. Int J Paediatr Dent 2009;19:176-85.
  • Soviero V, Haubek D, Trindade C, Da Matta T, Poulsen S. Prevalence and distribution of demarcated opacities and their sequelae in permanent 1st molars and incisors in 7 to 13-year-old Brazilian children. Acta Odontol Scand 2009;67:170-5.
  • Kemoli AM. Prevalence of molar incisor hypomineralisation in six to eight year-olds in two rural divisions in Kenya. East Afr Med J 2008;85:514-9.
  • Jasulaityte L, Weerheijm KL, Veerkamp JS. Prevalence of molar-incisor-hypomineralisation among children participating in the Dutch National Epidemiological Survey. Eur Arch Paediatr Dent 2008;9:218-23.
  • Lygidakis NA, Dimou G, Briseniou E. Molar-incisorhypomineralisation (MIH). Retrospective clinical study in Greek children. I. Prevalence and defect characteristics. Eur Arch Paediatr Dent 2008;9:200-6.
  • Kukleva MP, Petrova SG, Kondeva VK, Nihtyanova TI. Molar incisor hypomineralisation in 7-to-14-year old children in Plovdiv, Bulgaria--an epidemiologic study. Folia Med (Plovdiv) 2008;50:71-5.
  • Kuscu OO, Caglar E, Sandalli N. The prevalence and aetiology of molar-incisor hypomineralisation in a group of children in Istanbul. Eur J Paediatr Dent 2008;9:139-44.
  • Cho SY, Ki Y, Chu V. Molar incisor hypomineralization in Hong Kong Chinese children. Int J Paediatr Dent 2008;18:348-52.
  • Wogelius P, Haubek D, Poulsen S. Prevalence and distribution of demarcated opacities in permanent 1st molars and incisors in 6 to 8-year-old Danish children. Acta Odontol Scand 2008;66:58-64.
  • Muratbegovic A, Markovic N, Ganibegovic Selimovic M. Molar incisor hypomineralisation in Bosnia and Herzegovina: aetiology and clinical consequences in medium caries activity population. Eur Arch Paediatr Dent 2007;8:189-94.
  • Jasulaityte L, Veerkamp JS, Weerheijm KL. Molar incisor hypomineralization: review and prevalence data from the study of primary school children in Kaunas/Lithuania. Eur Arch Paediatr Dent 2007;8:87-94.
  • Preusser SE, Ferring V, Wleklinski C, Wetzel WE. Prevalence and severity of molar incisor hypomineralization in a region of Germany-a brief communication. J Public Health Dent 2007;67:148-50.
  • Fteita D, Ali A, Alaluusua S. Molar-incisor hypomineralization (MIH) in a group of school-aged children in Benghazi, Libya. Eur Arch Paediatr Dent 2006;7:92-5.
  • Calderara PC, Gerthoux PM, Mocarelli P, Lukinmaa PL, Tramacere PL, Alaluusua S. The prevalence of Molar Incisor Hypomineralisation (MIH) in a group of Italian school children. Eur J Paediatr Dent 2005;6:79-83.
  • Balmer RC, Laskey D, Mahoney E, Toumba KJ. Prevalence of enamel defects and MIH in non-fluoridated and fluoridated communities. Eur J Paediatr Dent 2005;6:209-12.
  • Dietrich G, Sperling S, Hetzer G. Molar incisor hypomineralisation in a group of children and adolescents living in Dresden (Germany). Eur J
  • Paediatr Dent 2003;4:133-7.
  • Fearne J, Anderson P, Davis DG. 3D X-ray microscopic study of the extent of variations in enamel density in first permanent molars with idiopathic enamel hypomineralization. Br Dent J 2004;196:634-8.
  • William V, Messer LB, Burrow MF. Molar incisor hypomineralization: review and recommendations for clinical management. Pediatr Dent 2006;28:224-32.
  • Crombie FA, Manton DJ, Weerheijm KL, Kilpatrick NM. Molar-Incisor Hypomineralisation: a survey of members of the Australian and New Zealand Society of Paediatric Dentistry. Aust Dent J 2008;53:160-6.
  • Lygidakis NA, Dimou G, Marinou D. Molar-incisor hypomineralisation (MIH). A retrospective clinical study in Greek children. II. Possible medical aetiological factors. Eur Arch Paediatr Dent 2008;9:207-17.
  • Jälevik B, Norén GJ, Klıngberg G, Barregård L. Etiologic factors influencing the prevalance of demarcated opacities in permanent first molars in a group of Swedish children. Eur J Oral Sci 2001;109:230-4.
  • Aine L, Backström MC, Mäki R, Kuusela AL, Koivisto AM, Ikonen RS, et al. Enamel defects in primary and permanent teeth of children born prematurely. J Oral Pathol Med 2000;29:403-9.
  • Seow WK. A study of the development of the permanent dentition in very low birthweight children. Pediatr Dent 1996;18:379-84.
  • Alaluusua S, Lukinmaa PL, Koskimies M, Pirinen S, Hölttä P, Kallio M, et al. Developmental dental defects associated with long breast-feeding. Eur J Oral Sci 1996;104:493-7.
  • Alaluusua S, Lukinmaa PL, Vartiainen T, Partanen M, Torppa J, Tuomisto J. Polychlorinated dibenzo-pdioxins and dibenzofurans via mother’s milk may cause developmental defects in the child’s teeth. Environ Toxicol Pharmacol 1996;1:193-7.
  • Smith DM, Miller J. Gastro-enteritis, coeliac disease and enamel hypoplasia. Br Dent J 1979;147:91-5.
  • Rugg-Gunn AJ, Al-Mohammadi SM, Butler TJ. Malnutrition and developmental defects of enamel in 2- to 6-year- old Saudi boys. Caries Res 1998;32:181-92.
  • Beentjes VE, Weerheijm KL, Groen HJ. Factors involved in the aetiology of molar-incisor hypomineralisation (MIH). Eur J Paediatr Dent 2002;3:9-13.
  • Fayle SA. Molar incisor hypomineralization: restorative management. Eur J Paediatr Dent 2003;4:121-6.
  • Reynolds EC. Calcium phosphate-based remineralization systems: scientific evidence? Aust Dent J 2008;53:268-73.
  • Mahoney EK. The treatment of localized hypoplastic and hypomineralized defects in first permanent molars. NZ Dent J 2001;97:101-5.
  • Jälevik B, Klingberg GA. Dental treatment, dental fear and behaviour management problems in children with severe enamel hypomineralization in their permanent first molars. Int J Paediatr Dent 2002;12:24-32.
  • Venezie RD, Vadiakas G, Christensen JR, Wright JT. Enamel pretreatment with sodium hypochlorite to enhance bonding in hypocalcified amelogenesis imperfecta: case report and SEM analysis. Pediatr Dent 1994;16:433-6.
  • Lygidakis NA, Chaliasou A, Siounas G. Evaluation of composite restorations in hypomineralized permanent molars: A four-year clinical study. Eur J Paediatr Dent 2003;4:143-8.
  • Jälevik B, Möller M. Evaluation of spontaneous space closure and development of permanent dentition after extraction of hypomineralized permanent first molars. Int J Paediatr Dent 2007;17:328-35.
  • Weerheijm KL. Molar incisor hypomineralization (MIH): clinical presentation, aetiology, and management. Dent Update 2004;31:9-12.

Büyük azı ve kesici diş hipomineralizasyonu: etiyolojisi ve kliniği

Yıl 2015, , 90 - 7, 21.04.2015
https://doi.org/10.17214/aot.71184

Öz

Büyük azı ve kesici diş hipomineralizasyonu (BAKH) daimi birinci molar ve daimi kesici dişlerin etkilendiği gelişimsel bir mine defektidir. Görülme durumu, %2.8 ile %44 arası değişmektedir. Etiyolojisi tam olarak bilinmemektedir, ancak çevresel etkenlerin ve sistemik durumların, büyük azı ve kesici diş hipomineralizasyonunun olası nedenleri arasında olabileceği düşünülmektedir. Hipomineralize molarlarda çürük oluşumuna yatkınlık ve ciddi restoratif problemler gözlenmektedir. Keserlerde ise sınırlı opak lezyonlar izlenirken, mine yıkımı yaygın değildir. BAKH gözlenen dişlerin tedavisi, mine defektinin şiddetine bağlıdır. Tedavisinde; risk belirlenmesi, erken teşhis, remineralizasyon ve hassasiyetin azaltılması, diş çürüklerinin ve sürme sonrası yıkımın önlenmesi, restorasyonlar, çekimler, oral hijyen ve ağız bakımından oluşan altı basamaklı yaklaşım önerilmektedir. Bu derlemenin amacı BAKH’nin teşhis ve tedavi yaklaşımları hakkında bilgi vermektir.

Kaynakça

  • Weerheijm KL, Jälevik B, Alaluusua S. Molar-incisor hypomineralization. Caries Res 2001;35:390-1.
  • Weerheijm KL, Duggal M, Mejàre I, Papagiannoulis L, Koch G, Martens LC, et al. Judgement criteria for molar-incisor hypomineralisation MIH in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003. Eur J Paediatr Dent 2003;4:110-3.
  • Koch G, Hallonsten AL, Ludvigsson N. Hansson BO, Hoist A, Ullbro C. Epidemiologic study of idiopatic enamel hypomineralization in permanent teeth of Sweedish children. Community Dent Oral Epidemiol 1987;15:279-85.
  • Jälevik B. Prevalence and Diagnosis of Molar-Incisor- Hypomineralisation (MIH): A systematic review. Eur Arch Paediatr Dent 2010;11:59-64.
  • Weerheijm KL. Molar incisor hypomineralisation. Eur J Paediatr Dent 2003;4:114-20.
  • Mathu-Muju K, Wright JT. Diagnosis and treatment of molar incisor hypomineralization. Compend Contin Educ Dent 2006;27:604-10.
  • Ogden AR, Pinhasi R, White WJ. Gross enamel hypoplasia in molars from subadults in a 16th-18th century London graveyard. Amer J Physic Anthropol 2007;133:957-66.
  • Willmott NS, Bryan RA, DuggalMS.Molar-incisor-hypomineralisation: a literature review. Eur Arch Paediatr Dent 2008;9:172-9.
  • Parikh DR, Ganesh M, Bhaskar V. Prevalence and characteristics of Molar Incisor Hypomineralisation (MIH) in the child population residing in Gandhinagar, Gujarat, India. Eur Arch Paediatr Dent 2012;13:21-6.
  • Balmer R, Toumba J, Godson J, Duggal M. The prevalence of molar incisor hypomineralisation in Northern England and its relationship to socioeconomic status and water fluoridation. Int J Paediatr Dent 2012;22:250-7.
  • Martínez Gómez TP, Guinot Jimeno F, Bellet Dalmau LJ, Giner Tarrida L. Prevalence of molar-incisor hypomineralisation observed using transillumination in a group of children from Barcelona (Spain). Int J Paediatr Dent 2012;22:100-9.
  • Mahoney EK, Morrison DG. Further examination of the prevalence of MIH in the Wellington region. NZ Dent J 2011;107:79-84.
  • Ghanim A, Morgan M, Mariño R, Bailey D, Manton D. Molar-incisor hypomineralisation: prevalence and defect characteristics in Iraqi children. Int J Paediatr Dent 2011;21:413-21.
  • Zawaideh FI, Al-Jundi SH, Al-Jaljoli MH. Molar incisor hypomineralisation: prevalence in Jordanian children and clinical characteristics. Eur Arch Paediatr Dent 2011;12:31-6.
  • Mahoney EK, Morrison DG. The prevalence of Molar Incisor Hypomineralisation (MIH) in Wainuiomata children. NZ Dent J 2009;105:121-7.
  • Kuscu OO, Caglar E, Aslan S, Durmusoglu E, Karademir A, Sandalli N. The prevalence of molar incisor hypomineralization (MIH) in a group of children in a highly polluted urban region and a windfarm-green energy island. Int J Paediatr Dent 2009;19:176-85.
  • Soviero V, Haubek D, Trindade C, Da Matta T, Poulsen S. Prevalence and distribution of demarcated opacities and their sequelae in permanent 1st molars and incisors in 7 to 13-year-old Brazilian children. Acta Odontol Scand 2009;67:170-5.
  • Kemoli AM. Prevalence of molar incisor hypomineralisation in six to eight year-olds in two rural divisions in Kenya. East Afr Med J 2008;85:514-9.
  • Jasulaityte L, Weerheijm KL, Veerkamp JS. Prevalence of molar-incisor-hypomineralisation among children participating in the Dutch National Epidemiological Survey. Eur Arch Paediatr Dent 2008;9:218-23.
  • Lygidakis NA, Dimou G, Briseniou E. Molar-incisorhypomineralisation (MIH). Retrospective clinical study in Greek children. I. Prevalence and defect characteristics. Eur Arch Paediatr Dent 2008;9:200-6.
  • Kukleva MP, Petrova SG, Kondeva VK, Nihtyanova TI. Molar incisor hypomineralisation in 7-to-14-year old children in Plovdiv, Bulgaria--an epidemiologic study. Folia Med (Plovdiv) 2008;50:71-5.
  • Kuscu OO, Caglar E, Sandalli N. The prevalence and aetiology of molar-incisor hypomineralisation in a group of children in Istanbul. Eur J Paediatr Dent 2008;9:139-44.
  • Cho SY, Ki Y, Chu V. Molar incisor hypomineralization in Hong Kong Chinese children. Int J Paediatr Dent 2008;18:348-52.
  • Wogelius P, Haubek D, Poulsen S. Prevalence and distribution of demarcated opacities in permanent 1st molars and incisors in 6 to 8-year-old Danish children. Acta Odontol Scand 2008;66:58-64.
  • Muratbegovic A, Markovic N, Ganibegovic Selimovic M. Molar incisor hypomineralisation in Bosnia and Herzegovina: aetiology and clinical consequences in medium caries activity population. Eur Arch Paediatr Dent 2007;8:189-94.
  • Jasulaityte L, Veerkamp JS, Weerheijm KL. Molar incisor hypomineralization: review and prevalence data from the study of primary school children in Kaunas/Lithuania. Eur Arch Paediatr Dent 2007;8:87-94.
  • Preusser SE, Ferring V, Wleklinski C, Wetzel WE. Prevalence and severity of molar incisor hypomineralization in a region of Germany-a brief communication. J Public Health Dent 2007;67:148-50.
  • Fteita D, Ali A, Alaluusua S. Molar-incisor hypomineralization (MIH) in a group of school-aged children in Benghazi, Libya. Eur Arch Paediatr Dent 2006;7:92-5.
  • Calderara PC, Gerthoux PM, Mocarelli P, Lukinmaa PL, Tramacere PL, Alaluusua S. The prevalence of Molar Incisor Hypomineralisation (MIH) in a group of Italian school children. Eur J Paediatr Dent 2005;6:79-83.
  • Balmer RC, Laskey D, Mahoney E, Toumba KJ. Prevalence of enamel defects and MIH in non-fluoridated and fluoridated communities. Eur J Paediatr Dent 2005;6:209-12.
  • Dietrich G, Sperling S, Hetzer G. Molar incisor hypomineralisation in a group of children and adolescents living in Dresden (Germany). Eur J
  • Paediatr Dent 2003;4:133-7.
  • Fearne J, Anderson P, Davis DG. 3D X-ray microscopic study of the extent of variations in enamel density in first permanent molars with idiopathic enamel hypomineralization. Br Dent J 2004;196:634-8.
  • William V, Messer LB, Burrow MF. Molar incisor hypomineralization: review and recommendations for clinical management. Pediatr Dent 2006;28:224-32.
  • Crombie FA, Manton DJ, Weerheijm KL, Kilpatrick NM. Molar-Incisor Hypomineralisation: a survey of members of the Australian and New Zealand Society of Paediatric Dentistry. Aust Dent J 2008;53:160-6.
  • Lygidakis NA, Dimou G, Marinou D. Molar-incisor hypomineralisation (MIH). A retrospective clinical study in Greek children. II. Possible medical aetiological factors. Eur Arch Paediatr Dent 2008;9:207-17.
  • Jälevik B, Norén GJ, Klıngberg G, Barregård L. Etiologic factors influencing the prevalance of demarcated opacities in permanent first molars in a group of Swedish children. Eur J Oral Sci 2001;109:230-4.
  • Aine L, Backström MC, Mäki R, Kuusela AL, Koivisto AM, Ikonen RS, et al. Enamel defects in primary and permanent teeth of children born prematurely. J Oral Pathol Med 2000;29:403-9.
  • Seow WK. A study of the development of the permanent dentition in very low birthweight children. Pediatr Dent 1996;18:379-84.
  • Alaluusua S, Lukinmaa PL, Koskimies M, Pirinen S, Hölttä P, Kallio M, et al. Developmental dental defects associated with long breast-feeding. Eur J Oral Sci 1996;104:493-7.
  • Alaluusua S, Lukinmaa PL, Vartiainen T, Partanen M, Torppa J, Tuomisto J. Polychlorinated dibenzo-pdioxins and dibenzofurans via mother’s milk may cause developmental defects in the child’s teeth. Environ Toxicol Pharmacol 1996;1:193-7.
  • Smith DM, Miller J. Gastro-enteritis, coeliac disease and enamel hypoplasia. Br Dent J 1979;147:91-5.
  • Rugg-Gunn AJ, Al-Mohammadi SM, Butler TJ. Malnutrition and developmental defects of enamel in 2- to 6-year- old Saudi boys. Caries Res 1998;32:181-92.
  • Beentjes VE, Weerheijm KL, Groen HJ. Factors involved in the aetiology of molar-incisor hypomineralisation (MIH). Eur J Paediatr Dent 2002;3:9-13.
  • Fayle SA. Molar incisor hypomineralization: restorative management. Eur J Paediatr Dent 2003;4:121-6.
  • Reynolds EC. Calcium phosphate-based remineralization systems: scientific evidence? Aust Dent J 2008;53:268-73.
  • Mahoney EK. The treatment of localized hypoplastic and hypomineralized defects in first permanent molars. NZ Dent J 2001;97:101-5.
  • Jälevik B, Klingberg GA. Dental treatment, dental fear and behaviour management problems in children with severe enamel hypomineralization in their permanent first molars. Int J Paediatr Dent 2002;12:24-32.
  • Venezie RD, Vadiakas G, Christensen JR, Wright JT. Enamel pretreatment with sodium hypochlorite to enhance bonding in hypocalcified amelogenesis imperfecta: case report and SEM analysis. Pediatr Dent 1994;16:433-6.
  • Lygidakis NA, Chaliasou A, Siounas G. Evaluation of composite restorations in hypomineralized permanent molars: A four-year clinical study. Eur J Paediatr Dent 2003;4:143-8.
  • Jälevik B, Möller M. Evaluation of spontaneous space closure and development of permanent dentition after extraction of hypomineralized permanent first molars. Int J Paediatr Dent 2007;17:328-35.
  • Weerheijm KL. Molar incisor hypomineralization (MIH): clinical presentation, aetiology, and management. Dent Update 2004;31:9-12.
Toplam 52 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Derleme
Yazarlar

Ebru Hazar Bodrumlu

Aysun Avşar Bu kişi benim

Yayımlanma Tarihi 21 Nisan 2015
Yayımlandığı Sayı Yıl 2015

Kaynak Göster

APA Hazar Bodrumlu, E., & Avşar, A. (2015). Büyük azı ve kesici diş hipomineralizasyonu: etiyolojisi ve kliniği. Acta Odontologica Turcica, 32(2), 90-7. https://doi.org/10.17214/aot.71184
AMA Hazar Bodrumlu E, Avşar A. Büyük azı ve kesici diş hipomineralizasyonu: etiyolojisi ve kliniği. Acta Odontol Turc. Nisan 2015;32(2):90-7. doi:10.17214/aot.71184
Chicago Hazar Bodrumlu, Ebru, ve Aysun Avşar. “Büyük Azı Ve Kesici Diş Hipomineralizasyonu: Etiyolojisi Ve kliniği”. Acta Odontologica Turcica 32, sy. 2 (Nisan 2015): 90-7. https://doi.org/10.17214/aot.71184.
EndNote Hazar Bodrumlu E, Avşar A (01 Nisan 2015) Büyük azı ve kesici diş hipomineralizasyonu: etiyolojisi ve kliniği. Acta Odontologica Turcica 32 2 90–7.
IEEE E. Hazar Bodrumlu ve A. Avşar, “Büyük azı ve kesici diş hipomineralizasyonu: etiyolojisi ve kliniği”, Acta Odontol Turc, c. 32, sy. 2, ss. 90–7, 2015, doi: 10.17214/aot.71184.
ISNAD Hazar Bodrumlu, Ebru - Avşar, Aysun. “Büyük Azı Ve Kesici Diş Hipomineralizasyonu: Etiyolojisi Ve kliniği”. Acta Odontologica Turcica 32/2 (Nisan 2015), 90-7. https://doi.org/10.17214/aot.71184.
JAMA Hazar Bodrumlu E, Avşar A. Büyük azı ve kesici diş hipomineralizasyonu: etiyolojisi ve kliniği. Acta Odontol Turc. 2015;32:90–7.
MLA Hazar Bodrumlu, Ebru ve Aysun Avşar. “Büyük Azı Ve Kesici Diş Hipomineralizasyonu: Etiyolojisi Ve kliniği”. Acta Odontologica Turcica, c. 32, sy. 2, 2015, ss. 90-7, doi:10.17214/aot.71184.
Vancouver Hazar Bodrumlu E, Avşar A. Büyük azı ve kesici diş hipomineralizasyonu: etiyolojisi ve kliniği. Acta Odontol Turc. 2015;32(2):90-7.