Prevalence of non-syndrome-related oligodontia in a group of Turkish children

Yıl 2021, Cilt: 38 Sayı: 1, 8 - 13, 01.01.2021

Canan Bayraktar Zuhal Kırzıoğlu

https://doi.org/10.17214/gaziaot.646511

Cited By: 1

Öz

Objective: This study aimed to determine the prevalence and distribution of non-syndrome-related oligodontia in Turkish-children in Isparta and its surroundings.

Materials and Method: The records of patients who were admitted to the Department of Pedodontics, Faculty of Dentistry of Süleyman Demirel University between 1999-2018, and diagnosed with oligodontia were searched. One-hundred-twelve individuals between the ages of 6 and 18 who did not have any systemic disorders, and missing ≥6 teeth except the third molars were included in the study. The distribution of detected tooth agenesis according to missing teeth, gender, and jaws and tooth agenesis patterns were examined. The frequency of tooth agenesis was given in numbers-percentages, and the Mann-Whitney U test was applied to the distribution of gender and missing teeth. The frequency analysis was calculated using Tooth Agenesis Code (TAC) values to determine tooth agenesis patterns.

Results: The incidence of non-syndrome-related oligodontia in Turkish-children in Isparta and its surroundings was found to be 0.08%. The number of missing teeth per individual was found to be 9.05 and the most commonly missing teeth were observed as lower/upper second premolars. When the tooth agenesis was compared between genders and jaws, the differences were not statistically significant. Commonly observed tooth agenesis patterns were a combination of premolars and lateral incisor.

Conclusion: According to the results, in Isparta and its surroundings, the presence of oligodontia was detected in 8 out of 10,000 children. Along with the early diagnosis, alternative treatment can be applied considering the severity and distribution of oligodontia.

Anahtar Kelimeler

Epidemiology, pediatric dentistry, tooth agenesis

Bir grup Türk çocuk popülasyonunda sendroma bağlı olmayan oligodonti prevalansı

Öz

Amaç: Bu çalışmanın amacı, Isparta ve çevresinde yaşayan Türk çocuklarında oligodontinin prevalansı ve dağılımını belirlemektir.
Gereç ve Yöntem: Süleyman Demirel Üniversitesi Diş Hekimliği Fakültesi, Pedodonti Anabilim Dalına 1999-2018 yılları arasında başvuran ve oligodonti tanısı konulmuş hasta kayıtları tarandı. Herhangi bir sistemik rahatsızlığı olmayan, üçüncü büyük azı dişleri hariç 6 ve daha fazla dişi eksik olan 6-18 yaş aralığında 112 birey çalışmaya dahil edildi. Saptanan diş eksikliklerinin, eksik diş sayılarına, dişlere, cinsiyete ve çenelere göre dağılımı ve diş eksikliği paternleri incelendi. Diş eksikliği görülme sıklığı sayı ve yüzde olarak tablolanıp, cinsiyet ve eksik dişlerin çenelere göre dağılımında Mann-Whitney U testi uygulandı. Diş eksikliği paternlerini belirlemek için Tooth Agenesis Code/Diş Eksikliği Kodu (TAC) değerleri verilerine frekans analizi yapıldı.
Bulgular: Çalışmamızda Isparta ve çevresinde yaşayan Türk çocuklarında, sendroma bağlı olmayan oligodontinin görülme sıklığı %0.08 oranında saptandı. Birey başına düşen konjenital eksik diş sayısı 9.05 olarak bulundu ve eksikliği en sık görülen dişler, alt ve üst 2. küçük azı dişleri olarak gözlendi. Diş eksikliği cinsiyetler ve çeneler arasında karşılaştırıldığında aradaki farklar istatistiksel olarak anlamlı bulunmadı. Yaygın izlenen eksik diş paternleri, üst çenede küçük azı ve lateral kesici kombinasyonu iken, alt çenede küçük azı dişleri ve lateral kesici dişlerin kombinasyonu şeklinde oldu.
Sonuç: Elde edilen sonuçlar dahilinde, Isparta ve çevresinde her on bin çocuktan 8’inde oligodonti varlığı tespit edildi. Oligodontinin erken teşhisi ile birlikte, şiddeti ve dağılımı göz önüne alınarak uygulanabilecek alternatif tedaviler önemli olabilir.

Anahtar Kelimeler

Çocuk diş hekimliği, diş eksikliği, epidemiyoloji

Kaynakça

• Schalk-van der Weide Y, Beemer FA, Faber JA, Bosman F. Symptomatology of patients with oligodontia. J Oral Rehabil 1994;21:247-61.
• Muller TP, Hill IN, Petersen AC, Blayney JR. A survey of congenitally missing permanent teeth. J Am Dent Assoc 1970;81:101-7.
• Maklin M, Dummett CO Jr, Weinberg R. A study of oligodontia in a sample of New Orleans children. ASDC J Dent Child 1979;46:478-82.
• Nordgarden H, Jensen JL, Storhaug K. Reported prevalence of congenitally missing teeth in two Norwegian counties. Community Dent Health 2002;19:258-61.
• Gkantidis N, Katib H, Oeschger E, Karamolegkou M, Topouzelis N, Kanavakis G. Patterns of non-syndromic permanent tooth agenesis in a large orthodontic population. Arch Oral Biol 2017;79:42-7.
• Altug-Atac AT, Erdem D. Prevalence and distribution of dental anomalies in orthodontic patients. Am J Orthod Dentofacial Orthop 2007;131:510-4.
• Gupta SK, Saxena P, Jain S, Jain D. Prevalence and distribution of selected developmental dental anomalies in an Indian population. J Oral Sci 2011;53:231-8.
• Arai K. Tooth agenesis patterns in Japanese orthodontic patients with nonsyndromic oligodontia. Am J Orthod Dentofacial Orthop 2019;156:238-47.
• Sen Tunc E, Koyuturk AE. Karadeniz bölgesi çocuklarında konjenital daimi diş eksikliği prevalansı. Atatürk Üniv Dis Hek Fak Derg 2006;16:37-40.
• Sisman Y, Uysal T, Gelgor IE. Hypodontia. Does the prevalence and distribution pattern differ in orthodontic patients? Eur J Dent 2007;1:167-73.
• Celikoglu M, Kazanci F, Miloglu O, Oztek O, Kamak H, Ceylan I. Frequency and characteristics of tooth agenesis among an orthodontic patient population. Med Oral Patol Oral Cir Bucal 2010;15:e797-801.
• Gökkaya B, Motro M, Kargül B. Prevalence and characteristics of non-syndromic hypodontia among Turkish orthodontic patient population. J Int Soc Prev Community Dent 2015;5:170-5.
• Gurbuz O, Ersen A, Dikmen B, Gumustas B, Gundogar M. The prevalence and distribution of the dental anomalies in the Turkish population. J Anat Soc India 2019;68:46-51.
• Aktan AM, Kara IM, Sener I, Bereket C, Ay S, Ciftci ME. Radiographic study of tooth agenesis in the Turkish population. Oral Radiol 2010;26:95-100.
• Kim YH. Investigation of hypodontia as clinically related dental anomaly: prevalence and characteristics. ISRN Dent 2011;2011:1-6.
• Cobourne MT. Familial human hypodontia--is it all in the genes? Br Dent J 2007;203:203-8.
• Nunn JH, Carter NE, Gillgrass TJ, Hobson RS, Jepson NJ, Meechan JG, et al. The interdisciplinary management of hypodontia: background and role of paediatric dentistry. Br Dent J 2003;194:245-51.
• van Wijk AJ, Tan SP. A numeric code for identifying patterns of human tooth agenesis: a new approach. Eur J Oral Sci 2006;114:97-101.
• Pearce N. Effect measures in prevalence studies. Environ Health Perspect 2004;112:1047-50.
• Polder BJ, Van’t Hof MA, Van der Linden FP, Kuijpers-Jagtman AM. A meta-analysis of the prevalence of dental agenesis of permanent teeth. Community Dent Oral Epidemiol 2004;32:217-26.
• Rølling S, Poulsen S. Agenesis of permanent teeth in 8138 Danish schoolchildren: prevalence and intra-oral distribution according to gender. Int J Paediatr Dent 2009;19:172-5.
• Shakra KA, Samer Alqaqaa D. Prevalence of hypodontia and oligodontia in a sample of orthodontic and pediatric dentistry patients at Prince Hashem bin Al-Hussein Military Hospital. J Royal Med Servic 2008;15:40-4.
• Ţenţ A, Todor L, Ciavoi G, Popovici-Mut AM, Domocoş D, Pogan MD, et al. Non-syndromic hypodontia of permanent dentition associated with other dental anomalies in children and adolescents. Rom J Morphol Embryol 2018;59:879-83.
• Rølling S, Poulsen S. Oligodontia in Danish schoolchildren. Acta Odontol Scand 2001;59:111-2.
• Behr M, Proff P, Leitzmann M, Pretzel M, Handel G, Schmalz G, et al. Survey of congenitally missing teeth in orthodontic patients in Eastern Bavaria. Eur J Orthod 2011;33:32-6.
• Ceyhan D. Diş eksikliğine sahip çocuk ve genç bireylerin dişsel ve genetik özelliklerinin tanımlanması [doktora tezi]. Isparta: Süleyman Demirel Üniversitesi; 2010.
• Gracco ALT, Zanatta S, Forin Valvecchi F, Bignotti D, Perri A, Baciliero F. Prevalence of dental agenesis in a sample of Italian orthodontic patients: an epidemiological study. Prog Orthod 2017;18:33.
• Sato A, Arai K. Estimation of tooth agenesis risks between tooth types in orthodontic patients with non-syndromic oligodontia. Orthod Waves 2019;78:49-55.
• Mattheeuws N, Dermaut L, Martens G. Has hypodontia increased in Caucasians during the 20th century? A meta-analysis. Eur J Orthod 2004;26:99-103.
• Garn SM, Lewis AB, Vicinus JH. Third molar polymorphism and its significance to dental genetics. J Dent Res 1963;42:1344-63.
• Brook AH. A unifying aetiological explanation for anomalies of human tooth number and size. Arch Oral Biol 1984;29:373-8.
• Kær I. Can the location of tooth agenesis and the location of initial bone loss seen in juvenile periodontitis be explained by neural developmental fields in the jaws? Acta Odontol Scand 1997;55:70-2.
• Pinho T, Tavares P, Maciel P, Pollmann C. Developmental absence of maxillary lateral incisors in the Portuguese population. Eur J Orthod 2005;27:443-9.
• Hua F, He H, Ngan P, Bouzid W. Prevalence of peg-shaped maxillary permanent lateral incisors: A meta-analysis. Am J Orthod Dentofacial Orthop 2013;144:97-109.
• Gundlach KK, Maus C. Epidemiological studies on the frequency of clefts in Europe and world-wide. J Craniomaxillofac Surg 2006;34:1-2.
• Tan SP, van Wijk AJ, Prahl-Andersen B. Severe hypodontia: identifying patterns of human tooth agenesis. Eur J Orthod 2011;33:150-4.
• Fournier BP, Bruneau MH, Toupenay S, Kerner S, Berdal A, Cormier-Daire V, et al. Patterns of dental agenesis highlight the nature of the causative mutated genes. J Dent Res 2018;97:1306–16.
• Vieira AR. Oral clefts and syndromic forms of tooth agenesis as models for genetics of isolated tooth agenesis. J Dent Res 2003;82:162–5.
• Stockton DW, Das P, Goldenberg M, D'Souza RN, Patel PI. Mutation of PAX9 is associated with oligodontia. Nature Genetics 2000;24:18-9.