Araştırma Makalesi

Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study

Cilt: 33 Sayı: 5 25 Ekim 2023
PDF İndir
TR EN

Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study

Öz

Background/Aims: This single-center study aimed to investigate the clinical outcomes and midterm mortality in patients who underwent carotid endarterectomy (CEA) for various indications. Methods: The study included 109 patients who underwent CEA at our institution. Demographic characteristics, indications for surgery, operative techniques, and early postoperative complications were recorded. Follow-up data were obtained for a mean period of 23.3 ± 17.2 months, and mortality causes, and neurological outcomes were analysed. Results: The mean age of the patients was 66.53 ± 8.00 years, with 73 men and 36 women. Indications for CEA included transient ischemic attack (TIA) in 21.1% and a history of ischemic stroke in 26.6% of patients. Overall, 86.2% had ipsilateral carotid stenosis of 70% or more. Most patients (89.9%) were operated under general anesthesia, and the conventional carotid endarterectomy technique was most employed (78.0%). The most frequent reconstruction method for the longitudinal carotid arteriotomy was Dacron patch plasty (56.0%). Early follow-up revealed low hospital mortality (0.9%) and limited postoperative complications (3.7% TIA, 1.8% major neurological complications, and 1.8% minor neurological complications). During the follow-up period, absolute survival was 87.0%. Conclusions: Our study demonstrates favourable early outcomes and acceptable long-term mortality rates following CEA. However, larger, and multicentre studies are warranted to further validate these results and enhance our understanding of CEA's long-term benefits

Anahtar Kelimeler

carotid artery stenosis, endarterectomy, mortality, stroke

Kaynakça

  1. GBD 2016 Stroke Collaborators. Global, regional, and national burden of stroke, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 2019 May;18(5):439–58.
  2. Topcuoglu MA, Ozdemir AO. Acute stroke management in Turkey: Current situation and future projection. European Stroke Journal. 2023 Jan 1;8(1_suppl):16–20.
  3. Flaherty ML, Kissela B, Khoury JC, Alwell K, Moomaw CJ, Woo D, et al. Carotid Artery Stenosis as a Cause of Stroke. Neuroepidemiology. 2012 Oct 11;40(1):36–41.
  4. Naylor R, Rantner B, Ancetti S, de Borst GJ, De Carlo M, Halliday A, et al. Editor’s Choice - European Society for Vascular Surgery (ESVS) 2023 Clinical Practice Guidelines on the Management of Atherosclerotic Carotid and Vertebral Artery Disease. Eur J Vasc Endovasc Surg. 2023 Jan;65(1):7–111.
  5. Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, et al. Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases. Kidney International. 2021 Oct 1;100(4):753–79.
  6. European Stroke Organisation guideline on endarterectomy and stenting for carotid artery stenosis [Internet]. [cited 2023 Jul 17]. Available from: https://journals.sagepub.com/doi/epub/10.1177/23969873211012121
  7. Ryu WS, Schellingerhout D, Hong KS, Jeong SW, Jang MU, Park MS, et al. White matter hyperintensity load on stroke recurrence and mortality at 1 year after ischemic stroke. Neurology. 2019 Aug 6;93(6):e578–89.
  8. Wang Y, Xu J, Zhao X, Wang D, Wang C, Liu L, et al. Association of Hypertension With Stroke Recurrence Depends on Ischemic Stroke Subtype. Stroke. 2013 May;44(5):1232–7.
  9. Hata J, Tanizaki Y, Kiyohara Y, Kato I, Kubo M, Tanaka K, et al. Ten year recurrence after first ever stroke in a Japanese community: the Hisayama study. Journal of Neurology, Neurosurgery & Psychiatry. 2005 Mar 1;76(3):368–72.
  10. GALA Trial Collaborative Group: General anaesthesia... - Google Akademik [Internet]. [cited 2023 Jul 16]. Available from: https://scholar.google.com/scholar_lookup?title=General%20anaesthesia%20versus%20local%20anaesthesia%20for%20carotid%20surgery%20(GALA)%3A%20a%20multicentre%2C%20randomised%20controlled%20trial&author=G.A.L.A.%20Trial%20Collaborative&publication_year=2008&pages=2132-2142

Kaynak Göster

APA
Yasar, E., & Bayram, M. (2023). Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study. Genel Tıp Dergisi, 33(5), 614-618. https://doi.org/10.54005/geneltip.1330055
AMA
1.Yasar E, Bayram M. Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study. Genel Tıp Derg. 2023;33(5):614-618. doi:10.54005/geneltip.1330055
Chicago
Yasar, Emre, ve Muhammed Bayram. 2023. “Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study”. Genel Tıp Dergisi 33 (5): 614-18. https://doi.org/10.54005/geneltip.1330055.
EndNote
Yasar E, Bayram M (01 Ekim 2023) Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study. Genel Tıp Dergisi 33 5 614–618.
IEEE
[1]E. Yasar ve M. Bayram, “Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study”, Genel Tıp Derg, c. 33, sy 5, ss. 614–618, Eki. 2023, doi: 10.54005/geneltip.1330055.
ISNAD
Yasar, Emre - Bayram, Muhammed. “Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study”. Genel Tıp Dergisi 33/5 (01 Ekim 2023): 614-618. https://doi.org/10.54005/geneltip.1330055.
JAMA
1.Yasar E, Bayram M. Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study. Genel Tıp Derg. 2023;33:614–618.
MLA
Yasar, Emre, ve Muhammed Bayram. “Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study”. Genel Tıp Dergisi, c. 33, sy 5, Ekim 2023, ss. 614-8, doi:10.54005/geneltip.1330055.
Vancouver
1.Emre Yasar, Muhammed Bayram. Clinical Outcomes and Midterm Mortality After Carotid Endarterectomy: A Single Center Study. Genel Tıp Derg. 01 Ekim 2023;33(5):614-8. doi:10.54005/geneltip.1330055