Koronavirüs hastalığı 2019 ve diğer viral pnömonilerde tespit edilen buzlu cam opasitelerinin bilgisayarlı tomografi doku analizi bulgularının karşılaştırılması

Yıl 2025, Cilt: 35 Sayı: 6, 1063 - 1071, 31.12.2025

Nusret Seher , Mehmet Öztürk , Mustafa Koplay , Abidin Kılınçer , Burcu Yormaz , Halil Özer , Nazlım Aktuğ Demir , Emine Uysal , Hakan Cebeci

https://doi.org/10.54005/geneltip.1452582

Öz

Amaç: Koronavirüs Hastalığı 2019’da (COVID-19) ve diğer viral pnömonilerde tespit edilen buzlu cam opasitelerini (BCO) ayırt etmede bilgisayarlı tomografi doku analizi (BTTA) bulgularının yararlılığını araştırmak.
Materyaller ve Yöntemler: COVID-19 ve COVID-19 dışı viral pnömoni için torasik bilgisayarlı tomografi (BT) incelemesi yapılan 120 hasta çalışmaya dahil edildi. Akciğer parankiminin heterojenitesi BT doku analizi özel yazılımı (Olea Medical, Fransa) ile değerlendirildi. CTTA, 8 first order intensitesi ve 3 gri seviye co-occurrence matrikse dayalı özellikleri içeriyordu.
Bulgular: Kontrast değeri COVID-19 BCO’da daha yüksekti (p = 0,006). Ortalama, medyan, skewness ve inverse difference moment (IDM) değerleri COVID-19 dışı BCO’da daha yüksekti (sırasıyla p değerleri 0, 0.001, 0.021 ve 0.006), ortalama mutlak sapma, varyans ve kontrast değerleri COVID-19 hastalarının normal akciğer parankimasında daha yüksekti (sırasıyla p değerleri 0.011, 0.023 ve 0.006). Her iki grupta hem BCO’dan hem de normal akciğer parankimasından elde edilen doku parametrelerinin ROC analizinde, doku parametrelerinin duyarlılık değerleri %58,3 ile %66,7 arasında değişirken, özgüllük değerleri %50 ile %66,7 arasında değişti.
Sonuç: BTTA parametreleri olan ortalama, medyan, skewness ve IDM değerleri COVID-19 ve COVID-19 dışı viral pnömonileri ayırt etmek için kullanılabilir.

Anahtar Kelimeler

BT , buzlu cam opasiteleri , COVID-19 , doku analizi , viral pnömoni

Comparison of computed tomography texture analysis findings of ground glass opacities detected in coronavirus disease 2019 and other viral pneumonias

Öz

Aim: To investigate the utility of computed tomography texture analysis (CTTA) findings in differentiating ground glass opacities (GGO) detected in Coronavirus Disease 2019 (COVID-19) and other viral pneumonias.

Methods: 120 patients who underwent thoracic computed tomography (CT) examination for COVID-19 and non-COVID-19 viral pneumonia were included in the study. The heterogeneity of the lung parenchyma was evaluated with CT tissue analysis special software (Olea Medical, France). CTTA included features based on 8 first order intensity and 3 gray level co-occurrence matrix.

Results: Contrast value was higher in COVID-19 GGO (p = 0.006). Mean, median, skewness and inverse difference moment (IDM) values were higher in non-COVID-19 GGO (p values 0, 0.001, 0.021 and 0.006, respectively) mean absolute deviation, variance and contrast values were higher in normal lung parenchyma of COVID-19 patients (p values 0.011, 0.023 and 0.006, respectively). In the ROC analysis of tissue parameters obtained from both GGO and normal lung parenchyma in both groups, the sensitivity values of tissue parameters ranged from 58.3% to 66.7%, while the specificity values ranged from 50% to 66.7%.

Conclusion: Mean, median, skewness and IDM values, which are CTTA parameters, can be used to distinguish COVID-19 and non- COVID-19 viral pneumonias.

Anahtar Kelimeler

Covid-19 , CT , Texture Analysis , Ground Glass Opacities , Viral Pneumonia

Kaynakça

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