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The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye

Cilt: 35 Sayı: 2 30 Nisan 2025
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The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye

Öz

ABSTRACT Background/Aims: The prevalence of Alzheimer’s Disease (AD) is unknown in many regions of our country. This study aimed to determine the prevalence of AD and its associated factors in Konya city centre located in the Central Anatolia region (Turkey). Methods: A study population of 240 subjects aged 65 and older were randomly selected from 14 family health centres. A face-to-face procedural interview, neurological and psychiatric tests, including the mini-mental state examination, clock drawing score, basic and instrumental daily life activities, mental status examination, and geriatric depression scale, were performed. Co-morbidities, used drugs, risks and protective factors were questioned. Results: The average age was 71.5 ± 5.8; 52.5% of them were male, 47.5% were women. The prevalence of AD was found 7.5%; 2.5% of them had mild, and 5% had advanced AD. While AD rates were higher in people who were illiterate, and primary-school graduates, it was lower in people with regular physical and mental activity. More abnormalities were found in general information, reasoning, abstraction, and executive functions in people with AD. As the daily and instrumental life activities deteriorated, the frequency of AD increased. Geriatric depression was higher in the AD group. Conclusions: Turkey is both a European and an Asian country and the locations of this study are urban areas of Central Anatolian Region. Our prevalence was slightly higher than current data of European countries. The presence of AD was found to be associated with mental state abnormalities, deteriorated daily and instrumental life activities and increased geriatric depression.

Anahtar Kelimeler

Cognitive Impairments, Alzheimer's Disease, Prevalance, Related Factors, Daily Living Activities, Geriatric Depression

Kaynakça

  1. 1. Emre M. Alzheimer’s Disease. In: Emre M. (ed) Basic Neurology Book, 1st edition, Gunes Publishing, Turkey, 2013: pp 955-962.
  2. 2. Lobo A, Launer LJ, Fratiglioni L, Andersen K, Di Carlo A, Breteler MM, et al. Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology 2000;54(11 Suppl 5):4-9.
  3. 3. Sosa-Ortiz AL, Acosta-Castillo I, Prince MJ. Epidemiology of dementias and Alzheimer's disease. Arch Med Res 2012;43(8):600-608.
  4. 4. Gurvit H, Emre M, Tinaz S, Bilgic B, Hanagasi H, Sahin H, et al. The prevalence of dementia in an urban Turkish population. Am J Alzheimers Dis Other Demen 2008;23(1):67-76.
  5. 5. World Health Organization. Sample size determination in health studies: a practical manual [e-book] WHO Library Cataloguing in Publication Data (NLM Classification: WA 950); 1991. [Internet]. Available from: https://apps.who.int/iris/handle/10665/40062. Accessed: 21.03.2021.
  6. 6. Güngen C, Ertan T, Eker E, Yaşar R, Engin F. Reliability and Validity of The Standardized Mini-Mental State Examination in The Diagnosis of Mild Dementia in Turkish Population. Turk J Psychiatr 2002;13: 273-281.
  7. 7. Folstein M, Folstein S, McHugh PR. Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12: 189-198.
  8. 8. Babacan-Yıldız G, Ur-Özçelik E, Kolukısa M, Işık AT, Gürsoy E, Kocaman G, et al. Validity and Reliability Studies of Modified Mini-Mental State Examination (MMSE-E) For Turkish Illiterate Patients With Diagnosis of Alzheimer Disease. Turk Psikiyatri Derg 2016;27(1):41-46.
  9. 9. Tekin S, Fairbanks LA, O'Connor S, Rosenberg S, Cummings JL. Activities of daily living in Alzheimer's disease: neuropsychiatric, cognitive, and medical illness influences. Am J Geriatr Psychiatry 2001;9 (1): 81-86.
  10. 10. Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of Illness in the Aged. The index of ADL: A Standardized measure of Biological and Psychosocial Function. JAMA 1963; 185: 914-919.

Kaynak Göster

APA
Cari Güngör, D., Güney, F., Uyar, M., Küçükkendirci, H., & Şahin, T. K. (2025). The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye. Genel Tıp Dergisi, 35(2), 325-333. https://doi.org/10.54005/geneltip.1522589
AMA
1.Cari Güngör D, Güney F, Uyar M, Küçükkendirci H, Şahin TK. The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye. Genel Tıp Derg. 2025;35(2):325-333. doi:10.54005/geneltip.1522589
Chicago
Cari Güngör, Dilara, Figen Güney, Mehmet Uyar, Hasan Küçükkendirci, ve Tahir Kemal Şahin. 2025. “The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye”. Genel Tıp Dergisi 35 (2): 325-33. https://doi.org/10.54005/geneltip.1522589.
EndNote
Cari Güngör D, Güney F, Uyar M, Küçükkendirci H, Şahin TK (01 Nisan 2025) The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye. Genel Tıp Dergisi 35 2 325–333.
IEEE
[1]D. Cari Güngör, F. Güney, M. Uyar, H. Küçükkendirci, ve T. K. Şahin, “The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye”, Genel Tıp Derg, c. 35, sy 2, ss. 325–333, Nis. 2025, doi: 10.54005/geneltip.1522589.
ISNAD
Cari Güngör, Dilara - Güney, Figen - Uyar, Mehmet - Küçükkendirci, Hasan - Şahin, Tahir Kemal. “The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye”. Genel Tıp Dergisi 35/2 (01 Nisan 2025): 325-333. https://doi.org/10.54005/geneltip.1522589.
JAMA
1.Cari Güngör D, Güney F, Uyar M, Küçükkendirci H, Şahin TK. The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye. Genel Tıp Derg. 2025;35:325–333.
MLA
Cari Güngör, Dilara, vd. “The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye”. Genel Tıp Dergisi, c. 35, sy 2, Nisan 2025, ss. 325-33, doi:10.54005/geneltip.1522589.
Vancouver
1.Dilara Cari Güngör, Figen Güney, Mehmet Uyar, Hasan Küçükkendirci, Tahir Kemal Şahin. The Current Prevalence of Alzheimer’s Disease and Related Factors in Individuals Aged 65 and over in Konya City Center of Türkiye. Genel Tıp Derg. 01 Nisan 2025;35(2):325-33. doi:10.54005/geneltip.1522589