Araştırma Makalesi

The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia

Cilt: 35 Sayı: 6 31 Aralık 2025
PDF İndir
TR EN

The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia

Öz

ABSTRACT Background/Aims: Pneumonia is one of the most important causes of mortality and morbidity worldwide. There is a need for simpler and easier markers that we can use to determine the prognosis of pneumonia patients in emergency departments. In this study, we aimed to evaluate the relationship between RDW/Albumin and BUN/Creatinine ratio and 30-day mortality, length of hospital stay and need for intubation in patients admitted to the emergency department and hospitalized in intensive care unit with a diagnosis of pneumonia. Methods: The study included 98 patients admitted to the emergency department between January 2022 and December 2023 and hospitalized in the intensive care unit due to pneumonia. Patients were divided into two groups as discharged and exited patients. The relationship between RDW/Albumin and BUN/Creatinine ratios and mortality was compared between the groups. Results: According to the findings of the study, RDW/Albumin ratio was found to significantly predict mortality in patients hospitalized from the emergency department to the intensive care unit. Another finding was that the BUN/Creatinine ratio also significantly predicted mortality (p<0.05). In the study, a low level positive correlation was found between BUN/Creatinine ratio and length of hospitalization and between CRP and length of hospitalization. In our study, it was found that albumin level decreased in the intubated group, while BUN (p=0.001), creatinine (p=0.028) and CRP (p<0.001) were high and significant in the intubated group. Conclusion: In our study, we found that RDW/Albumin and BUN/Creatinine ratios are parameters that can be used to predict 30-day mortality in pneumonia patients.

Anahtar Kelimeler

Albumin, Creatinine, mortality, Pneumonia

Kaynakça

  1. 1. Bennett JE, Dolin R, Blaser MJ. (2014), Mandell, Douglasand Bennett's Principles and Practice of Infectious Diseases E-Book: 2-Volume Set. Elsevier health sciences.
  2. 2. File TM. Community-acquired pneumonia. The Lancet. 2003; 362(9400): 1991-2001.
  3. 3. Niederman MS, Mandell LA, Anzueto A, Bass JB, Broughton WA, Campbell GD, et al. Guidelines for the management of adults with community-acquired pneumonia: diagnosis, assessment of severity, antimicrobial therapy, and prevention. Am J Resp Crit Care Med. 2001; 163(7): 1730-1754.
  4. 4. Lee JH, Chung HJ, Kim K, Jo YH, Rhee JE, Kim YJ, et al. Red cell distribution width as a prognostic marker in patients with community-acquired pneumonia. Am J Emerg Med. 2013; 31(1): 72-79.
  5. 5. Salvagno GL, Sanchis-Gomar F, Picanza A, Lippi G. Red blood cell distribution width: a simple parameter with multiple clinical applications. Crit Rev Clin Lab Sci. 2015; 52(2): 86-105.
  6. 6. Quinlan GJ, Martin GS, Evans TW. Albumin: biochemical properties and therapeutic potential. Hepatology. 2005; 41(6): 1211-1219.
  7. 7. Aman J, van der Heijden M, van Lingen A, Girbes AR, van Nieuw Amerongen GP, van Hinsbergh VW, et.al. Plasma protein levels are markers of pulmonary vascular permeability and degree of lung injury in critically ill patients with or at risk for acute lung injury/acute respiratory distress syndrome. Crit Care Med 2011; 39(1): 89-97.
  8. 8. Jeong JH, Heo M, Lee SJ, Jeong YY, Lee JD, Yoo JW. Clinical usefulness of red cell distribution width/albumin ratio to discriminate 28-day mortality in critically ill patients with pneumonia receiving invasive mechanical ventilation, compared with lacate/albumin ratio: a retrospective cohort study. Diagnostics. 2021;11(12):2344.
  9. 9. Özdemir A, Yüksel M, Ay MO, Kaya H, Doğru Ü, Bulut M. Investigation of the Relationship between Blood Urea Nitrogen/Serum Albumin Ratio and Clinical Course in Patients with COVID-19 Pneumonia. Kocaeli Medical Journal. 2022; 11(3): 157-171.
  10. 10. Lamberink HJ, Otte WM, Sinke MR, Lakens D, Glasziou PP, Tijdink JK, et al. Statistical power of clinical trials increased while effect size remained stable: an empirical analysis of 136,212 clinical trials between 1975 and 2014. Journal of Clinical Epidemiology. 2018; 102: 123-128.

Kaynak Göster

APA
Can, N. O., Arslan, Ş., Akpınar, F., & Doru, H. İ. (2025). The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia. Genel Tıp Dergisi, 35(6), 1072-1080. https://doi.org/10.54005/geneltip.1540057
AMA
1.Can NO, Arslan Ş, Akpınar F, Doru Hİ. The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia. Genel Tıp Derg. 2025;35(6):1072-1080. doi:10.54005/geneltip.1540057
Chicago
Can, Nazım Onur, Şenol Arslan, Furkan Akpınar, ve Halil İbrahim Doru. 2025. “The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia”. Genel Tıp Dergisi 35 (6): 1072-80. https://doi.org/10.54005/geneltip.1540057.
EndNote
Can NO, Arslan Ş, Akpınar F, Doru Hİ (01 Aralık 2025) The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia. Genel Tıp Dergisi 35 6 1072–1080.
IEEE
[1]N. O. Can, Ş. Arslan, F. Akpınar, ve H. İ. Doru, “The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia”, Genel Tıp Derg, c. 35, sy 6, ss. 1072–1080, Ara. 2025, doi: 10.54005/geneltip.1540057.
ISNAD
Can, Nazım Onur - Arslan, Şenol - Akpınar, Furkan - Doru, Halil İbrahim. “The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia”. Genel Tıp Dergisi 35/6 (01 Aralık 2025): 1072-1080. https://doi.org/10.54005/geneltip.1540057.
JAMA
1.Can NO, Arslan Ş, Akpınar F, Doru Hİ. The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia. Genel Tıp Derg. 2025;35:1072–1080.
MLA
Can, Nazım Onur, vd. “The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia”. Genel Tıp Dergisi, c. 35, sy 6, Aralık 2025, ss. 1072-80, doi:10.54005/geneltip.1540057.
Vancouver
1.Nazım Onur Can, Şenol Arslan, Furkan Akpınar, Halil İbrahim Doru. The Power of RDW/Albumin and BUN/Creatinine Ratio in Predicting Mortality in Patients Admitted to the Emergency Department and Hospitalized in Intensive Care Unit with Pneumonia. Genel Tıp Derg. 01 Aralık 2025;35(6):1072-80. doi:10.54005/geneltip.1540057