Araştırma Makalesi

Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups

Cilt: 35 Sayı: 1 28 Şubat 2025
PDF İndir
TR EN

Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups

Öz

Background/Aims: Chronic cough is a prevalent issue in pediatric patients and is among the most common reasons for referral to pediatric allergists, significantly affecting quality of life and often necessitating specialized evaluation. This study aimed to analyze the clinical characteristics, etiologies, and management of chronic cough in children, providing insights into age-related prevalence. Methods: Pediatric patients presenting with chronic cough to our pediatric allergy clinic between May 1,2023 and May 31, 2024 were included in this retrospective study. Patients previously diagnosed with allergic diseases or evaluated at other clinics were excluded. Medical records were reviewed for demographics, cough characteristics, familial and environmental factors, and treatments. Results: Of the 267 patients included, 54.7% were boys, and the median age was 6.99 (interquartile range (IQR) 4.47-11.54) years. Asthma (39%), protracted bacterial bronchitis (PBB) (25.8%), and upper airway cough syndrome (UACS) (22.1%) were the most common diagnoses. PBB was more prevalent in younger patients, whereas asthma was dominant in older age groups. Regardless of the cough etiology, antibiotic use was noted in 67.8% of patients before applying to the pediatric allergy outpatient clinic. Tobacco smoke exposure was present in 40.1% of patients. Familial asthma history was significantly more common in patients with asthma (p=0.04). Conclusions: This study underscores the importance of distinguishing chronic cough etiologies in children to prevent mismanagement and overuse of antibiotics. While asthma, PBB, and UACS were among the primary causes, many other potential diagnoses also warrant consideration. Comprehensive assessments are essential for accurate diagnosis, and a multi-disciplinary approach may enhance management outcomes.

Anahtar Kelimeler

asthma, chronic cough, upper airway cough syndrome, protracted bacterial bronchitis

Kaynakça

  1. 1. Chang AB, Oppenheimer JJ, Irwin RS; CHEST Expert Cough Panel. Managing Chronic Cough as a Symptom in Children and Management Algorithms: CHEST Guideline and Expert Panel Report. Chest. 2020;158(1):303-329. doi: 10.1016/j.chest.2020.01.042. PMID: 32179109.
  2. 2. Marchant JM, Newcombe PA, Juniper EF, Sheffield JK, Stathis SL, Chang AB. What is the burden of chronic cough for families? Chest. 2008;134(2):303-309. doi: 10.1378/chest.07-2236. PMID: 18641100.
  3. 3. Mukerji SS, Yenduri NJS, Chiou E, Moonnumakal SP, Bedwell JR. A multi-disciplinary approach to chronic cough in children. Laryngoscope Investig Otolaryngol. 2022;7(2):409-416. doi: 10.1002/lio2.778. PMID: 35434349; PMCID: PMC9008181.
  4. 4. Chang AB, Robertson CF, Van Asperen PP, Glasgow NJ, Mellis CM, Masters IB, Teoh L, Tjhung I, Morris PS, Petsky HL, Willis C, Landau LI. A multicenter study on chronic cough in children: burden and etiologies based on a standardized management pathway. Chest. 2012;142(4):943-950. doi: 10.1378/chest.11-2725. PMID: 22459773.
  5. 5. Chang AB, Glomb WB. Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-based clinical practice guidelines. Chest. 2006;129(1 Suppl):260S-283S. doi: 10.1378/chest.129.1_suppl.260S. PMID: 16428719.
  6. 6. Morice AH, Millqvist E, Bieksiene K, Birring SS, Dicpinigaitis P, Domingo Ribas C, Hilton Boon M, Kantar A, Lai K, McGarvey L, Rigau D, Satia I, Smith J, Song WJ, Tonia T, van den Berg JWK, van Manen MJG, Zacharasiewicz A. ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J. 2020;55(1):1901136. Doi: 10.1183/13993003.01136-2019. PMID: 31515408; PMCID: PMC6942543.
  7. 7. Kantar A, Chang AB, Shields MD, Marchant JM, Grimwood K, Grigg J, Priftis KN, Cutrera R, Midulla F, Brand PLP, Everard ML. ERS statement on protracted bacterial bronchitis in children. Eur Respir J. 2017;50(2):1602139. Doi: 10.1183/13993003.02139-2016. PMID: 28838975.
  8. 8. Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis SZ, McCool FD, McCrory DC, Prakash UBS, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Hammond CS, Tarlo SM. Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006;129(1 Suppl):1S-23S. doi: 10.1378/chest.129.1_suppl.1S. PMID: 16428686; PMCID: PMC3345522.
  9. 9. Asilsoy S, Bayram E, Agin H, Apa H, Can D, Gulle S, Altinoz S. Evaluation of chronic cough in children. Chest. 2008;134(6):1122-1128. doi: 10.1378/chest.08-0885. PMID: 18689594.
  10. 10. Karabel M, Kelekçi S, Karabel D, Gürkan MF. The evaluation of children with prolonged cough accompanied by American College of Chest Physicians guidelines. Clin Respir J. 2014;8(2):152-9. doi: 10.1111/crj.12052. PMID: 23981451.

Kaynak Göster

APA
Turgay Yağmur, İ. (2025). Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups. Genel Tıp Dergisi, 35(1), 155-161. https://doi.org/10.54005/geneltip.1582368
AMA
1.Turgay Yağmur İ. Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups. Genel Tıp Derg. 2025;35(1):155-161. doi:10.54005/geneltip.1582368
Chicago
Turgay Yağmur, İrem. 2025. “Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups”. Genel Tıp Dergisi 35 (1): 155-61. https://doi.org/10.54005/geneltip.1582368.
EndNote
Turgay Yağmur İ (01 Şubat 2025) Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups. Genel Tıp Dergisi 35 1 155–161.
IEEE
[1]İ. Turgay Yağmur, “Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups”, Genel Tıp Derg, c. 35, sy 1, ss. 155–161, Şub. 2025, doi: 10.54005/geneltip.1582368.
ISNAD
Turgay Yağmur, İrem. “Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups”. Genel Tıp Dergisi 35/1 (01 Şubat 2025): 155-161. https://doi.org/10.54005/geneltip.1582368.
JAMA
1.Turgay Yağmur İ. Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups. Genel Tıp Derg. 2025;35:155–161.
MLA
Turgay Yağmur, İrem. “Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups”. Genel Tıp Dergisi, c. 35, sy 1, Şubat 2025, ss. 155-61, doi:10.54005/geneltip.1582368.
Vancouver
1.İrem Turgay Yağmur. Evaluation of Patients Presenting with Chronic Cough to the Pediatric Allergy Clinic According to Age Groups. Genel Tıp Derg. 01 Şubat 2025;35(1):155-61. doi:10.54005/geneltip.1582368