The effect of frailty and cognitive impairment on rational use of medicine in older adults
Öz
Abstract
Background/Aim: To determine whether frailty and cognitive changes affect rational use of medicines in older individuals.
Methods: The descriptive cross-sectional study was conducted in eastern Turkey. A total of 251 older individuals aged 60 years were included. In addition to demographic and medical characteristics, frailty status, mental status, and rational use of medicines were measured in a 25-35-minute questionnaire administration period.
Results: The frailty scores of the participants were 1.65±1.22, rational use of medicines scores were 72.16±16.31, and mental status scores were 20.83±5.46. Rational use of medicines had a statistically significant negative correlation with frailty (r= -,314) and a statistically significant positive correlation with mental status (r= ,595**). There was a statistically significant difference in rational use of medicines according to polypharmacy, history of hospitalization, educational status, income, age, and cohabitant variables (p<0.05). Regression analysis showed that the final model of rational use of medicines including mental status score, income, educational status, age, and cohabitant variables explained 43% of the total variance.
Conclusions: Rational use of medicines was not adequate in the older individuals and cognitive changes and frailty negatively affected rational use of medicines. Accordingly, it is recommended that mental status and frailty factors should be taken into consideration to ensure that the use of medicines in older individuals is in accordance with the principles of rational use of medicines.
Anahtar Kelimeler
rational use of medicines, frailty, cognitive changes, mental status, older adults
Destekleyen Kurum
none
Etik Beyan
Approval was obtained from Inonu University Health Sciences Non-Interventional Clinical Research Ethics Committee (2021/1750). The study was conducted in accordance with the Declaration of Helsinki. All participants provided voluntary consent online and their participation was confidential. Permission to use the scale was obtained from the authors.
Teşekkür
The authors would like to thank all the participants.
Kaynakça
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