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Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux

Cilt: 35 Sayı: 1 28 Şubat 2025
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Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux

Bu makalenin ilk hali 31 Aralık 2024 tarihinde yayımlandı. https://dergipark.org.tr/tr/pub/geneltip/article/1519733

Düzeltme Notu

The ethics committee, conflict of interest statement, financial disclosure and author contributions section, which was missing due to a technical problem, was added to the article titled "Yaşar M, Taş BM. Evaluation of systemic inflammatory marker in patients with laryngopharyngeal reflux. General Medicine Journal. 2024;34(6):822-6."

Öz

Abstract Aim: It was aimed to investigate whether systemic inflammation markers have diagnostic value in laryngopharyngeal reflux disease. Materials and Methods: This retrospective study was conducted including 32 patients with laryngopharyngeal reflux and 27 subjects with vocal cord nodul. Patients with laryngopharyngeal reflux were evaluated as Group 1, and subjects with vocal cord nodul as Group 2. Patient files were scanned. Neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and systemic inflammation index values were calculated. In addition, the previously filled Reflux symptom index and the Reflux sign scores performed by videoendoscopic examination were noted. Results: While the mean age was 43.21±13.26 years in Group 1, it was 38.04±10.39 years in Group 2. While there were 12 male and 20 female patients in Group 1, there were 12 male and 15 female patients in Group 2. When Neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and systemic inflammation index values were examined, no statistically significant difference was found between Group 1 and Group 2 (p>0.05). Reflux symptom index and Reflux sign scores were significantly higher in Group-1 (p<0.05). There was a significant positive correlation between Reflux symptom index and Reflux sign scores. Conclusion: In our study, no significant difference was found in the Neutrophil/lymphocyte ratio, platelet/lymphocyte ratio and systemic inflammation index values used in the follow-up of many diseases compared to the control group in laryngopharyngeal reflux patients and and had no diagnostic value. While Reflux symptom index and Reflux sign scores were found to be significantly higher in laryngopharyngeal reflux patients compared to the control group, they were significantly positively correlated with each other. KeyWords: Laryngopharyngeal Reflux; Lymphocyte ; Neutrophil; Reflux Symptom Index; Reflux Finding Score

Anahtar Kelimeler

Laryngopharyngeal Reflux;, Reflux Symptom Index, Reflux Finding Score, Neutrophil;, Lymphocyte

Kaynakça

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  3. 3. Abraham ZS, Kahinga AA. Utility of reflux finding score and reflux symptom index in diagnosis of laryngopharyngeal reflux disease. Laryngoscope Investig Otolaryngol. 2022 Jun; 7(3): 785–789.
  4. 4. Belafsky PC, Postma GN, Koufman JA. Validity and reliability of the reflux symptom index (RSI). J Voice. 2002;16(2):274-7.
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  6. 6. Atan D, İkincioğulları A, Köseoğlu S, Özcan KM, Çetin MA, Ensari S, et al. New Predictive Parameters of Bell's Palsy: Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio. Balkan Med J. 2015 Apr;32(2):167-70.
  7. 7. Torun S, Tunc BD, Suvak B, Yildiz H, Tas A, Sayilir A, et al. Assessment of neutrophil-lymphocyte ratio in ulcerative colitis: a promising marker in predicting disease severity. Clin Res Hepatol Gastroenterol. 2012 Oct;36(5):491-7.
  8. 8. Arslan H, Çandar T, Kuran S, Akmansu ŞH, Kocatürk S. New inflammatory parameters in laryngopharyngeal reflux. J Laryngol Otol. 2016 Sep;130(9):878-82.
  9. 9. Bhat T, Teli S, Rijal J, Bhat H, Raza M, Khoueiry G, Meghani M, et al. Neutrophil to lymphocyte ratio and cardiovascular diseases: a review. Expert Rev Cardiovasc Ther. 2013 Jan;11(1):55-9.
  10. 10. Yao C, Zhang Z, Yao Y, Xu X, Jiang Q, Shi D. Predictive value of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio for acute deep vein thrombosis after total joint arthroplasty: a retrospective study. J Orthop Surg Res. 2018 Feb 27;13(1):40.

Kaynak Göster

APA
Yaşar, M., & Taş, B. M. (2025). Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux. Genel Tıp Dergisi, 35(1), 222-222. https://doi.org/10.54005/geneltip.1646650
AMA
1.Yaşar M, Taş BM. Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux. Genel Tıp Derg. 2025;35(1):222-222. doi:10.54005/geneltip.1646650
Chicago
Yaşar, Murat, ve Burak Mustafa Taş. 2025. “Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux”. Genel Tıp Dergisi 35 (1): 222-22. https://doi.org/10.54005/geneltip.1646650.
EndNote
Yaşar M, Taş BM (01 Şubat 2025) Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux. Genel Tıp Dergisi 35 1 222–222.
IEEE
[1]M. Yaşar ve B. M. Taş, “Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux”, Genel Tıp Derg, c. 35, sy 1, ss. 222–222, Şub. 2025, doi: 10.54005/geneltip.1646650.
ISNAD
Yaşar, Murat - Taş, Burak Mustafa. “Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux”. Genel Tıp Dergisi 35/1 (01 Şubat 2025): 222-222. https://doi.org/10.54005/geneltip.1646650.
JAMA
1.Yaşar M, Taş BM. Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux. Genel Tıp Derg. 2025;35:222–222.
MLA
Yaşar, Murat, ve Burak Mustafa Taş. “Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux”. Genel Tıp Dergisi, c. 35, sy 1, Şubat 2025, ss. 222-, doi:10.54005/geneltip.1646650.
Vancouver
1.Murat Yaşar, Burak Mustafa Taş. Evalution of systemic inflammatory marker in patients with laryngopharyngeal reflux. Genel Tıp Derg. 01 Şubat 2025;35(1):222-. doi:10.54005/geneltip.1646650