Araştırma Makalesi

PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS

Cilt: 35 Sayı: 4 29 Ağustos 2025
PDF İndir
EN TR

PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS

Öz

Backgrounds/Aims: This study aimed to investigate the prevalence of hepatic artery (HA) atherosclerosis and the factors affecting HA atherosclerosis in adults with abdominal aorta (AA) atherosclerosis detected by computed tomography angiography (CTA). Methods: 296 adults with AA atherosclerosis who underwent CTA of the AA for various reasons in 2020 at xxx University Hospital were included in this study. The presence and type of atherosclerosis in the common HA, right, and left HA were evaluated. Celiac trunk anatomy, HA anatomy, presence of left gastric artery (LGA) atherosclerosis, calcium scores of other visceral branches of the AA, and total AA atherosclerosis score were evaluated in all patients. These parameters were compared between patients with and without HA atherosclerosis. Results: HA atherosclerosis was found in 25 cases (8.4%). The most common type of HA atherosclerosis was calcified plaque in the common HA. The mean age of patients with HA atherosclerosis was statistically significantly higher than those without (70±7.67 vs 66±9.3, p= 0.041). There was a statistically significant correlation between HA anatomy and HA atherosclerosis (p= 0.034). Post hoc analyses revealed that HA atherosclerosis was more frequent in patients with type 2 and type 3 HA anatomy (p values 0.027 and 0.044, respectively). Prevalence of the LGA atherosclerosis was significantly higher in patients with HA atherosclerosis than those without (12% vs 0.3%, p= 0.002). Total renal artery (RA) calcium score, superior mesenteric artery (SMA) calcium score, splenic artery (SA) calcium score, AA total atherosclerosis score, and total iliac artery (IA) calcium score were significantly higher in patients with HA atherosclerosis than in patients without (p values <0.001, <0.001, <0.001, 0.029, <0.001, respectively). In logistic regression analysis, SMA calcium score (HR: 1.898, 95% CI: 1.002-3.607, p= 0.05), SA calcium score (HR: 2.626, 95% CI: 1.485-4.643, p= 0.001), and total IA calcium score (HR: 3.063, 95% CI: 1.162-8.077, p= 0.024) were found to be independent risk factors for HA atherosclerosis. Conclusions: In this study, the prevalence of HA atherosclerosis was 8.4% in adults with AA atherosclerosis. SMA, SA, and total IA calcium scores were found to be independent risk factors for AA atherosclerosis.

Anahtar Kelimeler

Hepatic Artery, Atherosclerosis, Abdominal aorta, Celiac artery

Kaynakça

  1. 1. Bergheanu SC, Bodde MC, Jukema JW. Pathophysiology and treatment of atherosclerosis: Current view and future perspective on lipoprotein modification treatment. Neth Heart J. 2017;25(4):231-42.
  2. 2. Maluf D, Clark BD, Cotterell AH, Posner MP, Fisher RA. Massive hepatic artery atherosclerosis of an otherwise suitable donor liver: a case report. Transplant Proc. 2004;36(5):1438-41.
  3. 3. Hamby BA, Ramirez DE, Loss GE, Bazan HA, Smith TA, Bluth E, et al. Endovascular treatment of hepatic artery stenosis after liver transplantation. J Vasc Surg. 2013;57(4):1067-72.
  4. 4. Goldsmith LE, Wiebke K, Seal J, Brinster C, Smith TA, Bazan HA, et al. Complications after endovascular treatment of hepatic artery stenosis after liver transplantation. J Vasc Surg. 2017;66(5):1488-96.
  5. 5. Uflacker R. Atlas of vascular anatomy: an angiographic approach. Lippincott Williams & Wilkins; 2007.
  6. 6. Michels NA. Blood supply and anatomy of the upper abdominal organs, with a descriptive atlas. (No Title). 1955.
  7. 7. Takx RA, Zanen P, Leiner T, van der Graaf Y, de Jong PA. The interdependence between cardiovascular calcifications in different arterial beds and vascular risk factors in patients at high cardiovascular risk. Atherosclerosis. 2015;238(1):140-6.
  8. 8. Jacobs PC, Prokop M, Oen AL, van der Graaf Y, Grobbee DE, Mali WP. Semiquantitative assessment of cardiovascular disease markers in multislice computed tomography of the chest: interobserver and intraobserver agreements. J Comput Assist Tomogr. 2010;34(2):279-84.
  9. 9. Vellar ID. The blood supply of the biliary ductal system and its relevance to vasculobiliary injuries following cholecystectomy. Aust N Z J Surg. 1999;69(11):816-20.
  10. 10. Saiura A, Umekita N, Inoue S, Maeshiro T, Miyamoto S, Matsui Y, et al. Benign biliary stricture associated with atherosclerosis. Hepatogastroenterology. 2001;48(37):81-2.

Kaynak Göster

APA
Arslan Sarıkaya, S. (2025). PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS. Genel Tıp Dergisi, 35(4), 649-658. https://doi.org/10.54005/geneltip.1660461
AMA
1.Arslan Sarıkaya S. PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS. Genel Tıp Derg. 2025;35(4):649-658. doi:10.54005/geneltip.1660461
Chicago
Arslan Sarıkaya, Sevtap. 2025. “PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS”. Genel Tıp Dergisi 35 (4): 649-58. https://doi.org/10.54005/geneltip.1660461.
EndNote
Arslan Sarıkaya S (01 Ağustos 2025) PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS. Genel Tıp Dergisi 35 4 649–658.
IEEE
[1]S. Arslan Sarıkaya, “PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS”, Genel Tıp Derg, c. 35, sy 4, ss. 649–658, Ağu. 2025, doi: 10.54005/geneltip.1660461.
ISNAD
Arslan Sarıkaya, Sevtap. “PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS”. Genel Tıp Dergisi 35/4 (01 Ağustos 2025): 649-658. https://doi.org/10.54005/geneltip.1660461.
JAMA
1.Arslan Sarıkaya S. PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS. Genel Tıp Derg. 2025;35:649–658.
MLA
Arslan Sarıkaya, Sevtap. “PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS”. Genel Tıp Dergisi, c. 35, sy 4, Ağustos 2025, ss. 649-58, doi:10.54005/geneltip.1660461.
Vancouver
1.Sevtap Arslan Sarıkaya. PREVALENCE OF HEPATIC ARTERY ATHEROSCLEROSIS AND FACTORS AFFECTING HEPATIC ARTERY ATHEROSCLEROSIS IN PATIENTS WITH ABDOMINAL AORTA ATHEROSCLEROSIS. Genel Tıp Derg. 01 Ağustos 2025;35(4):649-58. doi:10.54005/geneltip.1660461