Kırım Kongo Kanamalı Ateşinde Hemogram Parametrelerinin Tanısal Değeri

Yıl 2021, Cilt: 31 Sayı: 2, 101 - 104, 30.06.2021

Emine Doğan Sadık Girişgin Birsen Ertekin Osman Lütfi Demirci

https://doi.org/10.15321/GenelTipDer.2021.293

Öz

Giriş: Ülkemizde son yıllarda Kırım Kongo kanamalı ateşi (KKKA), yüksek mortalitesi nedeni ile dikkat çekmektedir.

Amaç: KKKA’da meydana gelen inflamatuar sürecin, tam kan parametreleri üzerine olan etkisini araştırmaktır.

Gereç ve Yöntem:01.01.2010 – 31.12.2011 tarihleri arasında acil servisimize, kene ile temas şikayetiyle başvuran toplam 5260 hasta retrospektif olarak incelendi. Klinik olarak şüpheli 80 vakaya yapılan serolojik inceleme sonunda KKKA tanısı için 40 hastada pozitif ve 40 hastada negatif sonuç bulundu. Sağlıklı gönüllü 40 kişiden kontrol grubu oluşturuldu. Hastalardan başvuru sırasında alınan tüm hemogram parametreleri, hasta ve kontrol grubu ile ayrı ayrı karşılaştırıldı.

Bulgular: KKKA pozitif ve negatif olan hasta grubu, kontrol grubu ile kıyaslandığında; lökosit, nötrofil, red cell distribution width (RDW), mean platelet volume (MPV), nötrofil-lenfosit oranı (NLR) ve trombosit-lenfosit oranı (PLR) değerleri sadece KKKA pozitif olan grupta anlamlı tespit edildi. Oysa lenfosit ve platelet değerleri her iki grupta da anlamlı bulunmuştur (p≤0.01).

Sonuç: Bu çalışmada elde edilen verilere göre özellikle acil servislerde ucuz, kolay ve yaygın olarak kullanılabilecek bu tam kan parametreleri KKKA tanısında klinisyenlere yardımcı olabilir.

Anahtar Kelimeler

kırım kongo kanamalı ateşi, nötrofil lenfosit oranı, platelet-lenfosit oranı, ortalama platelet hacmi, kırmızı kan hücreleri dağılım genişliği

Diagnostic Value of Hemogram Parameters in Crimean-Congo Hemorrhagic Fever

Öz

Introduction: Crimean-Kongo hemorrhagic fever (CKHF) has pulled attention in recent years due to its high mortality rate.

Objective: To investigate the effect of the inflammatory process in Crimean-Kongo hemorrhagic fever on the complete blood count parameters.

Material and Methods: A total of 5260 patients who had presented to theemergency room of our hospital due to tick contact between 01 January 2010 and 31 December 2011 were analyzed retrospectively. Serological examination yielded 40 positive and 40 negative results for 80 cases with suspicion of CKHF. Forty healthy volunteers constituted the control group. All of the complete blood cell count parameters that were examined on admission were compared separately with the patient and the control group.

Results: When CKHF positive and negative patient groups were compared with the control group, the neutrophil, red cell distribution width (RDW), mean platelet volume (MPV), neutrophil/lymphocyte ratio (NLR) and the platelet/lymphocyte ratio (PLR) values were found to be significant in the CKHF-positive group only. However, the lymphocyte and the platelet values were found to be significant in both groups (p≤0.01).

Conclusion: The results of the present study suggest that complete blood count parameters, which are inexpensive, easy and widely used, may be useful for the diagnosis of Crimean-Kongo hemorrhagic fever in the emergency room.

Anahtar Kelimeler

Crimean-Kongo hemorrhagic fever, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, mean platelet volume, red cell distribution width

Kaynakça

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