BibTex RIS Kaynak Göster

İntrakranial lipomlar: Yerleşim yerleri ile birlikte bilgisayarlı tomografi ve manyetik rezonans görüntüleme bulguları

Yıl 2015, Cilt: 25 Sayı: 4, 126 - 131, 01.12.2015

Öz

Amaç: Bu çalışmanın amacı, nadir doğumsal malformasyonlardan olan intrakranial lipomların bilgisayarlı tomografi BT ve manyetik rezonans görüntüleme MRG bulgularını incelemek, klinik bulgularını ve birliktelik gösterdikleri malformasyonları tespit etmek ve lezyon yerleri ile hem semptomlar hem de kalfikasyon varlığı arasındaki ilişkiyi tespit etmektir. Gereç ve yöntem: Mart 2010-Mart 2015 tarihleri arasında tanı alan intrakranial lipoma sahip 57 hastanın 22 erkek ve 35 kadın, ortalama yaş 50, 2-89 arası yaş BT ve MRG bulgularını geriye dönük değerlendirdik. 25 hastanın BT, 32 hastanın MRG incelemesi mevcuttu. Lezyonların BT dansiteleri ölçüldü, görüntüleme bulguları, lezyon hacimleri, semptomlar ve birliktelik gösterdikleri lezyonlar tespit edildi. Lezyon yerleri ile hem semptomlar hem de kalsifikasyon varlığı arasındaki ilişki kikare testi kullanılarak araştırıldı. Bulgular: Lezyonların yerleşim yerleri şu şekilde izlendi; interhemisferik fissür n=22 , sol kuadrigeminal sistern n=10 , korpus kallozum n=10 , interserebellar fissür n=4 , sağ kuadrigeminal sistern n=3 , interpedinküler sistern n=3 , silvian fissür n=2 , koroid pleksus n=2 , sol akustik kanal n=1 . Ortalama lipom hacmi 4±3,047 mm3 idi. En sık semptom 9 hastada görülen baş ağrısı idi. Lezyon yerleri, ne semptomlar p=0,394 ile ne de kalsifikasyon varlığı p=0,552 ile anlamlı ilişki göstermedi. Sonuç: BT ve MRG tipik özellikleriyle intrakranial lipomlara tanı koyabilmektedir ve de bu lezyonların birliktelik gösterdikleri diğer malformasyonları da ortaya koyabilmektedir. BT ve MRG özelliklerinin bilinmesi ayırıcı tanıyı kolaylaştırmaktadır

Kaynakça

  • Eghwrudjakpor PPO, Kurisaka M, Fukuoka M, Mori K. Intracra- nial lipomas: current perspectives in their diagnosis and treatmet. Br J Neurosurg 1992;6:139-44.
  • Friedman RB, Segal R, Latchaw RE. Computerized tomographic and magnetic resonance imaging of intracranial lipoma. J Neuro- surg 1986;65:407-10.
  • Truwit CL, Barkovich AJ. Pathogenesis of intracranial lipoma: an MR study in 42 patients. Am J Roentgenol 1990;155:855-65.
  • Baeesa SS, Higgins MJ, Ventureyra CG. Dorsal brain stem lipomas: case report. Neurosurgery 1996;38:1031-5.
  • Uchino A, Hasuo K, Matsumoto S, Masuda K. MRI of dorsal me- sencephalic lipomas Clin Imaging 1993;17:12-6.
  • Macpherson RI, Holgate RC, Gudeman SK. Midline central ner- vous system lipomas in children. J Can Assoc Radiol 1987;38:264- 70.
  • Donati F, Vasella F, Kaiser G, Blumberg A. Intracranial lipomas. Neuropediatrics 1992;23:32-8.
  • Catala M, Lazareth JP, Coquillo F, Binoche T. Dorsal mesencep- halic lipoma with inferior collicular hypoplasia: case report and review of literature. Clin Neurol Neurosurg 1997;99:271-5.
  • Demaerel P, Van De Gaer P, Wilms G, Baert AL. Interhemisphe- ric lipoma with variable callosal dysgenesis: relationship betwe- en embryology, morphology, and symptomatology. Eur Radiol 1996;6:904-9.
  • Gómez-Gosálvez FA, Menor-Serrano F, Téllez de Meneses-Loren- zo M, et al. Intracranial lipomas in pediatrics: a retrospective study of 20 patients. Rev Neurol 2003;37:515-21.
  • Sasaki H, Yoshida K, Wakamoto H, Otani M, Toya S. Lipomas of the frontal lobe. Clin Neurol Neurosurg 1996;98:27–31.
  • Futami K, Kimura A, Yamashita J. Intracranial lipoma associa- ted with cerebral saccular aneurysm: case report. J Neurosurg 1992;77:640-2.
  • Seidl Z, Vaneckova M, Vitak T. Intracranial lipomas: a retrospecti- ve study. Neuroradiol J 2007;20:30-6.
  • Barkovich AJ. Congenital malformations of the brain and skull. In: Barkovich AJ (ed) Pediatric neuroimaging, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2000;265-6.
  • Fitoz S, Atasoy C, Erden I, Akyar S. Intracranial lipoma with ext- racranial extension through foramen ovale in a patient with en- cephalocraniocutaneous lipomatosis syndrome. Neuroradiology 2002;44:175-8.
  • Gaskin CM, Helms CA. Lipomas, lipoma variants, and well-dif- ferentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. Am J Roentgenol 2004;182:733-9.
  • Maiuri F, Cirillo S, Simonetti L, De Simone MR, Gangeni M. Int- racranial lipomas: diagnostic and therapeutic considerations. J Neurosurg Sci 1988;32:161-7.
  • Ichikawa T, Kumazaki T, Mizumura S, et al. Intracranial lipomas: demonstration by computed tomography and magnetic resonance imaging. J Nippon Med Sch 2000;67:388-91.
  • Saatci I, Aslan C, Renda Y, Besim A. Parietal lipoma associated with cortical dysplasia and abnormal vasculature: case report and review of the literature. Am J Neuroradiol 2000;21:1718-21.
  • Ozcelik O, Acer N, Doganay S, Ertekin T, Cinar S. Estimation of cerebral surface area of the newborn brain using stereological met- hods. Erciyes Med J 2013;35:136-41.
  • Verga P. Lipoma ed osteolipomi della pia madre. Tumori 1929;15:321.
  • Hadecke J, Buchfelder M, Hans-Jürgen T, Schneyer U. Multiple intracranial lipoma: a case report. Neurosurg Rev 1997;20:282-7.
  • Yildiz H, Hakyemez B, Koroglu M, Yesildag A, Baykal B. Int- racranial lipomas: importance of localization. Neuroradiology 2006;48:1-7.
  • Feldman RP, Marcovici A, Lasala PA. Intracranial lipoma of the sylvian fissure: case report and review of the literature. J Neuro- surg 2001;94:515-9.
  • Sinson G, Gennarelli TA, Wells GB. Suprasellar osteolipoma: case report. Surg Neurol 1998;50:457-60.
  • Friede RL. Osteolipomas of the tuber cinereum. Arch Pathol Lab Med 1977;101:369–72.
  • List CF, Holt JF, Everett M. Lipoma of the corpus callsoum. Am J Roentgenol Radium Ther 1946;55:125-34.
  • Warakaulle DR, Anslow P. Differential diagnosis of intracranial lesions with high signal on T1 or low signal on T2-weighted MRI. Clin Radiol 2003;58:922-933.
  • Drevelegas A: Extra-axial brain tumors. Eur Radiol 2005;15:453- 67.
  • Iaconetta G, Carvalho GA, Vorkapic P, Samii M. Intracranial epi- dermoid tumor: a case report and review of the literature. Surg Neurol 2001;55:218-22.
  • Chen S, Ikawa F, Kurisu K, et al. Quantitative MR evaluation of intracranial epidermoid tumors by fast fluid-attenuated inversion recovery imaging and echo- planar diffusion-weighted imaging. Am J Neuroradiol 2001;22:1089-96.
  • Karantanas AH. MR imaging of intracranial epidermoid tumors: specific diagnosis with Turbo-FLAIR pulse sequence. Comput Med Imaging Graph 2001;25:249-55.

Intracranial lipomas: Lesion localizations, computed tomography and magnetic resonance imaging findings

Yıl 2015, Cilt: 25 Sayı: 4, 126 - 131, 01.12.2015

Öz

Objectives: The purpose of this study is to evaluate computed tomography CT and magnetic resonance imaging MRI findings of intracranial lipomas which are rare congenital malformations, to determine clinical findings and associated malformations, and to determine the relationships between lesion localization and symptoms as well as between lesion localization and presence of calcifica- tion. Material and methods: We retrospectively evaluated CT and MRI findings of 57 patients 22 male and 35 female patients with median age of 50 who received a diagnosis of intracranial lipoma between March 2010 and March 2015. CT examina- tions of 25 patients and MRI examinations of 32 patients were available. CT densities of lesions were assessed, imaging findings, lesion volumes, symptoms, and associated lesions were determined. The relationships between lesion localization and symptoms as well as between lesion localization and presence of calcification were evaluated using using x2 test. Results: Localizations of the lesions were as follows; interhemispheric fissure n=22 , left quadrigeminal cistern n=10 , corpus callosum n=10 , intercerebellar fissure n=4 right quadrigeminal cistern n=3 , interpeduncular cistern n=3 , sylvian fissure n=2 , choroid plexus n=2 , and left acoustic canal n=1 . Mean lipoma volume was 4±3,047 mm3. The most common symptom was headache demonstrated in 9 patients. Lesion localizations did not show any significant relationship neither with symptoms p=0,394 nor with presence of calcification p=0,552 . Conclusion: CT and MRI can diagnose intracranial lipomas with typical findings and detect associated malformations. To know CT and MRI findings of them makes it easier to differentiate them from the other lesions

Kaynakça

  • Eghwrudjakpor PPO, Kurisaka M, Fukuoka M, Mori K. Intracra- nial lipomas: current perspectives in their diagnosis and treatmet. Br J Neurosurg 1992;6:139-44.
  • Friedman RB, Segal R, Latchaw RE. Computerized tomographic and magnetic resonance imaging of intracranial lipoma. J Neuro- surg 1986;65:407-10.
  • Truwit CL, Barkovich AJ. Pathogenesis of intracranial lipoma: an MR study in 42 patients. Am J Roentgenol 1990;155:855-65.
  • Baeesa SS, Higgins MJ, Ventureyra CG. Dorsal brain stem lipomas: case report. Neurosurgery 1996;38:1031-5.
  • Uchino A, Hasuo K, Matsumoto S, Masuda K. MRI of dorsal me- sencephalic lipomas Clin Imaging 1993;17:12-6.
  • Macpherson RI, Holgate RC, Gudeman SK. Midline central ner- vous system lipomas in children. J Can Assoc Radiol 1987;38:264- 70.
  • Donati F, Vasella F, Kaiser G, Blumberg A. Intracranial lipomas. Neuropediatrics 1992;23:32-8.
  • Catala M, Lazareth JP, Coquillo F, Binoche T. Dorsal mesencep- halic lipoma with inferior collicular hypoplasia: case report and review of literature. Clin Neurol Neurosurg 1997;99:271-5.
  • Demaerel P, Van De Gaer P, Wilms G, Baert AL. Interhemisphe- ric lipoma with variable callosal dysgenesis: relationship betwe- en embryology, morphology, and symptomatology. Eur Radiol 1996;6:904-9.
  • Gómez-Gosálvez FA, Menor-Serrano F, Téllez de Meneses-Loren- zo M, et al. Intracranial lipomas in pediatrics: a retrospective study of 20 patients. Rev Neurol 2003;37:515-21.
  • Sasaki H, Yoshida K, Wakamoto H, Otani M, Toya S. Lipomas of the frontal lobe. Clin Neurol Neurosurg 1996;98:27–31.
  • Futami K, Kimura A, Yamashita J. Intracranial lipoma associa- ted with cerebral saccular aneurysm: case report. J Neurosurg 1992;77:640-2.
  • Seidl Z, Vaneckova M, Vitak T. Intracranial lipomas: a retrospecti- ve study. Neuroradiol J 2007;20:30-6.
  • Barkovich AJ. Congenital malformations of the brain and skull. In: Barkovich AJ (ed) Pediatric neuroimaging, 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2000;265-6.
  • Fitoz S, Atasoy C, Erden I, Akyar S. Intracranial lipoma with ext- racranial extension through foramen ovale in a patient with en- cephalocraniocutaneous lipomatosis syndrome. Neuroradiology 2002;44:175-8.
  • Gaskin CM, Helms CA. Lipomas, lipoma variants, and well-dif- ferentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. Am J Roentgenol 2004;182:733-9.
  • Maiuri F, Cirillo S, Simonetti L, De Simone MR, Gangeni M. Int- racranial lipomas: diagnostic and therapeutic considerations. J Neurosurg Sci 1988;32:161-7.
  • Ichikawa T, Kumazaki T, Mizumura S, et al. Intracranial lipomas: demonstration by computed tomography and magnetic resonance imaging. J Nippon Med Sch 2000;67:388-91.
  • Saatci I, Aslan C, Renda Y, Besim A. Parietal lipoma associated with cortical dysplasia and abnormal vasculature: case report and review of the literature. Am J Neuroradiol 2000;21:1718-21.
  • Ozcelik O, Acer N, Doganay S, Ertekin T, Cinar S. Estimation of cerebral surface area of the newborn brain using stereological met- hods. Erciyes Med J 2013;35:136-41.
  • Verga P. Lipoma ed osteolipomi della pia madre. Tumori 1929;15:321.
  • Hadecke J, Buchfelder M, Hans-Jürgen T, Schneyer U. Multiple intracranial lipoma: a case report. Neurosurg Rev 1997;20:282-7.
  • Yildiz H, Hakyemez B, Koroglu M, Yesildag A, Baykal B. Int- racranial lipomas: importance of localization. Neuroradiology 2006;48:1-7.
  • Feldman RP, Marcovici A, Lasala PA. Intracranial lipoma of the sylvian fissure: case report and review of the literature. J Neuro- surg 2001;94:515-9.
  • Sinson G, Gennarelli TA, Wells GB. Suprasellar osteolipoma: case report. Surg Neurol 1998;50:457-60.
  • Friede RL. Osteolipomas of the tuber cinereum. Arch Pathol Lab Med 1977;101:369–72.
  • List CF, Holt JF, Everett M. Lipoma of the corpus callsoum. Am J Roentgenol Radium Ther 1946;55:125-34.
  • Warakaulle DR, Anslow P. Differential diagnosis of intracranial lesions with high signal on T1 or low signal on T2-weighted MRI. Clin Radiol 2003;58:922-933.
  • Drevelegas A: Extra-axial brain tumors. Eur Radiol 2005;15:453- 67.
  • Iaconetta G, Carvalho GA, Vorkapic P, Samii M. Intracranial epi- dermoid tumor: a case report and review of the literature. Surg Neurol 2001;55:218-22.
  • Chen S, Ikawa F, Kurisu K, et al. Quantitative MR evaluation of intracranial epidermoid tumors by fast fluid-attenuated inversion recovery imaging and echo- planar diffusion-weighted imaging. Am J Neuroradiol 2001;22:1089-96.
  • Karantanas AH. MR imaging of intracranial epidermoid tumors: specific diagnosis with Turbo-FLAIR pulse sequence. Comput Med Imaging Graph 2001;25:249-55.
Toplam 32 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Original Article
Yazarlar

Serkan Güneyli Bu kişi benim

Kazım Serhan Keleşoğlu Bu kişi benim

Mesut Sivri Bu kişi benim

Hasan Erdoğan Bu kişi benim

Mustafa Koplay Bu kişi benim

Yayımlanma Tarihi 1 Aralık 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 25 Sayı: 4

Kaynak Göster

Vancouver Güneyli S, Keleşoğlu KS, Sivri M, Erdoğan H, Koplay M. İntrakranial lipomlar: Yerleşim yerleri ile birlikte bilgisayarlı tomografi ve manyetik rezonans görüntüleme bulguları. Genel Tıp Derg. 2015;25(4):126-31.