Laparoskopik kolesistektomide karbondioksit pnömoperitoneumun beyin natriüretik peptid ve troponin I üzerine etkileri

Yıl 2015, Cilt: 25 Sayı: 3, 85 - 88, 01.09.2015

Hande Köksal Sevil Kurban

Öz

Bu çalışmanın amacı, LK sırasında CO2 pnömoperitoneumun BNP ve cTnI içeren kardiyak belirteçler üzerine etkisini araştırmaktır.Amaç: Bu çalışmanın amacı laparoskopik kolesistektomi sırasında karbondioksit pnömoperitoneumun beyin natriüretik peptid BNP ve troponin I’yı cTnI içeren kardiyak belirteçler üzerine etkisini araştırmaktır. Gereç ve yöntem: Hastalar; laparoskopik kolesistektomi uygulanan hastalar Grup I ve genel anestezi altında diğer cerrahi işlem uygulanan hastalar Grup II olarak iki gruba ayrıldı. Kan örnekleri preoperatif, peroperatif dönemde ve ameliyatın 24. saatinde alındı. Troponin I ve BNP düzeyleri ölçüldü. Bulgular: Hiçbir hastada ameliyat sırasında elektrokardiyografide akut ST değişikliği saptanmadı. Grup I’de ameliyattın 24. saatindeki BNP düzeyleri hem preoperatif hem de peroperatif dönem BNP düzeylerinden anlamlı yüksek bulundu. Grup II’nin BNP düzeyleri değerlendirildiğinde aralarında anlamlı fark saptanmadı. Grup I ve II’de cTnI düzeyleri arasında anlamlı fark saptanmadı. Sonuç: Laparoskopik kolesistektomiye bağlı pnömoperitoneum kardiyak iskemik olaya yol açmadan hemodinamik değişlikliğe yol açmaktadır

Anahtar Kelimeler

Laparoskopik kolesistektomi, pnömoperitoneum, beyin natriüretik peptid, troponin I

The role of tumor markers including CA125, CA19.9 and carcinoembriyonic antigen in acute appendicitis

Öz

Objectives: The purpose of this study is to investigate the effects of carbondioxide pneumoperitoneum on brain natriuretic peptide BNP and cardiac markers including troponin I TnI during laparoscopic cholecystectomy LC . Material and methods: Patients performed LC were grouped as Group I and patients performed different surgical procedures under general anesthesia were grouped as Group II. Blood samples were obtained in preoperative and peroperative periods and 24 hours after the surgery, Troponin I and BNP levels were measured. Results: Acute ST segment changes in the electrocardiography were not determined in any patient during the operation. For Group I, the BNP levels at the 24th hour of the operation was significantly higher than both preoperative and peroperative periods whereas there were no significant differences in BNP levels in Group II. Between Group I and II no significant differences in cTnI levels were determined. Conclusion: Pneumoperitoneum due to LC causes hemodynamic changes without lead- ing to any cardiac ischemic conditions

Anahtar Kelimeler

Laparoscopic cholecystectomy, pneumoperitoneum, brain natriuretic peptide, cardiac troponin I

Kaynakça

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