BibTex RIS Kaynak Göster

Lomber 3 vertebra yerleşimli agressif osteoblastom

Yıl 2012, Cilt: 22 Sayı: 3, 109 - 111, 01.01.2012

Öz

Osteoblastom, sıklıkla vertebralarda ve uzun kemiklerde bulunur. 20 yaş öncesi yaşlarda nadir görülen iyi huylu kemik tümörüdür. Tüm kemik tümörlerinin % 1’inden daha azını oluşturur. Bu kemik tümörü ileri derecede vaskülerdir. Başlangıç semptomu sırt ağrısıdır. Tanıda direk grafiler ve tomografik görüntülemeler kullanılır. Posterior vertebra proçeslerinde litik görüntüler ile ve biyopsi veya tam cerrahi eksizyonla kesin tanısı konulur. Primer tedavisi tam cerrahi eksizyondur. İnkomplet rezeksiyonlarda, anrezektabıl vakalarda ve rekürren olgularda radyoterapi ve kemoterapi faydalı olabilir. Agressif osteoblastom tanılı bu olgumuza inkomplet rezeksiyon sonrası kliniğimizde adjuvan 3-Boyutlu Konformal Radyoterapi uygulandı. Bu olgumuz, literatür ışığında tedavi yöntemi ve toksisite değerlendirmesi de yapılarak nadir bir olgu olarak sunuldu

Kaynakça

  • Samdani A, Torre-Healy A, Chou D, Cahill AM, Storm PB. Treatment of osteoblastoma at C7: A multidisciplinary approach. A case report and review of the literature.Eur Spine J 2009;18:196-200.
  • Boriani S, Capanna R, Donati D, Levine A, Picci P, Savini R. Osteoblastoma of the spine. Clin Orthop 1992;278:37–45.
  • McLeod RA, Dahlin DC, Beabout JW. The spectrum of osteoblastoma. AJR Am J Roentgenol 1976;126:321-5.
  • Pettine KA, Klassen RA. Osteoid osteoma and osteoblastoma of the spine. J Bone Jt Surg Am 1986;68:354–61.
  • Lucas DR, Unni KK, McLeod RA, O’Connor MI, Sim FH Osteoblastoma: Clinicopathologic study of 306 cases. Hum Pathol 1994;25:117–34.
  • Jackson RP, Reckling FW, Mants FA. Osteoid osteoma and osteoblastoma. Similar histologic lesions with different natural histories. Clin Orthop 1977;128:303–13.
  • Kroon HM, Schurmans J. Osteoblastoma: Clinical and radiological findings in 98 new cases. Radiol 1990;175:783– 90.
  • Raskas DS, Graziano GP, Herzenberg JE, Heidelberger KP, Hensinger RN. Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord 1992;5:204–11.
  • Berberoglu S, Oguz A, Aribal E, Ataoglu O. Osteoblastoma response to radiotherapy and chemotherapy. Med Pediatr Oncol 1997;28:305-9.
  • Jaffe HL. Benign osteoblastoma. Bull Hosp Joint Dis 1956;17:141-51.
  • Lichtenstein L. Benign osteoblastoma, a category of osteoid and bone forming tumors other than classical osteoid osteoma, which may be mistaken for giant-cell tumor or osteogenic sarcoma. Cancer 1956;9:1044–52.
  • 12-Ozaki T, Liljenqvist U, Hillmann A, Halm H, Lindner N, Gosheger G, Winkelmann W. Osteoid osteoma and osteoblastoma of the spine. Experiences with 22 patients. Clin Orthop Relat Res 2002; (397): 394-402.
  • Zileli M, Cagli S, Basdemir G, Ersahin Y. Osteoid osteomas and osteoblastomas of the spine. Neurosurg Focus 2003;15:E5.
  • Mark RJ, Poen J, Tran LM, Fu YS, Selch MT, Parker RG . Postirradiation sarcomas. A single-institution study and review of the literature. Cancer 1994;73:2653–62.

Agressive osteoblastoma located on 3. lumbar spine

Yıl 2012, Cilt: 22 Sayı: 3, 109 - 111, 01.01.2012

Öz

Osteoblastoma is frequently located in spine and long bones. It is a benign bone tumor rarely seen before age of 20 and consists of less than 1% of all bone tumors. This bone tumor is excessively vascular. The initial symptom is dorsalgia. Direct graphics and tomographic imaging are used for diagnosis. Definite diagnosis is made with presence of lytic imaging in spine processes and biopsy or complete surgical excision. Primary treatment is complete surgical excision. Radiotherapy and chemotherapy may be beneficial in incomplete resections, unresectable cases and recurrent cases. The subject who was diagnosed as aggressive osteoblastoma was applied adjuvant 3-dimensional conformal radiotherapy in our clinic following incomplete resection. This subject is presented as a rare case in the light of literature and by making a toxicity assessment.

Kaynakça

  • Samdani A, Torre-Healy A, Chou D, Cahill AM, Storm PB. Treatment of osteoblastoma at C7: A multidisciplinary approach. A case report and review of the literature.Eur Spine J 2009;18:196-200.
  • Boriani S, Capanna R, Donati D, Levine A, Picci P, Savini R. Osteoblastoma of the spine. Clin Orthop 1992;278:37–45.
  • McLeod RA, Dahlin DC, Beabout JW. The spectrum of osteoblastoma. AJR Am J Roentgenol 1976;126:321-5.
  • Pettine KA, Klassen RA. Osteoid osteoma and osteoblastoma of the spine. J Bone Jt Surg Am 1986;68:354–61.
  • Lucas DR, Unni KK, McLeod RA, O’Connor MI, Sim FH Osteoblastoma: Clinicopathologic study of 306 cases. Hum Pathol 1994;25:117–34.
  • Jackson RP, Reckling FW, Mants FA. Osteoid osteoma and osteoblastoma. Similar histologic lesions with different natural histories. Clin Orthop 1977;128:303–13.
  • Kroon HM, Schurmans J. Osteoblastoma: Clinical and radiological findings in 98 new cases. Radiol 1990;175:783– 90.
  • Raskas DS, Graziano GP, Herzenberg JE, Heidelberger KP, Hensinger RN. Osteoid osteoma and osteoblastoma of the spine. J Spinal Disord 1992;5:204–11.
  • Berberoglu S, Oguz A, Aribal E, Ataoglu O. Osteoblastoma response to radiotherapy and chemotherapy. Med Pediatr Oncol 1997;28:305-9.
  • Jaffe HL. Benign osteoblastoma. Bull Hosp Joint Dis 1956;17:141-51.
  • Lichtenstein L. Benign osteoblastoma, a category of osteoid and bone forming tumors other than classical osteoid osteoma, which may be mistaken for giant-cell tumor or osteogenic sarcoma. Cancer 1956;9:1044–52.
  • 12-Ozaki T, Liljenqvist U, Hillmann A, Halm H, Lindner N, Gosheger G, Winkelmann W. Osteoid osteoma and osteoblastoma of the spine. Experiences with 22 patients. Clin Orthop Relat Res 2002; (397): 394-402.
  • Zileli M, Cagli S, Basdemir G, Ersahin Y. Osteoid osteomas and osteoblastomas of the spine. Neurosurg Focus 2003;15:E5.
  • Mark RJ, Poen J, Tran LM, Fu YS, Selch MT, Parker RG . Postirradiation sarcomas. A single-institution study and review of the literature. Cancer 1994;73:2653–62.
Toplam 14 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Case Report
Yazarlar

Yılmaz Tezcan Bu kişi benim

Mehmet Koç Bu kişi benim

Yayımlanma Tarihi 1 Ocak 2012
Yayımlandığı Sayı Yıl 2012 Cilt: 22 Sayı: 3

Kaynak Göster

Vancouver Tezcan Y, Koç M. Lomber 3 vertebra yerleşimli agressif osteoblastom. Genel Tıp Derg. 2012;22(3):109-11.