THE PREVALENCE OF BLASTOCYSTIS HOMINIS AND GASTROINTESTINAL SYSTEM PARASITES IN PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA DIAGNOSIS

Yıl 2024, Cilt: 34 Sayı: 5, 656 - 659, 30.10.2024

Cem Selim , İrfan Yavaş , Rafiye Ciftciler

https://doi.org/10.54005/geneltip.1452726

Öz

ABSTRACT
Introduction
Multiple myeloma (MM) is a hematological malignancy characterized by the presence of abnormal clonal plasma cells in the bone marrow. Immunodeficiency seen in patients with multiple myeloma (MM) is a serious problem. Blastocystis sp. is found in the gastrointestinal tract and can infect humans.

Background/ Aims
In our study, we compared the prevalence of B.hominis and other parasites with the control group and patients who had recently been diagnosed with multiple myeloma.
Material-Methods
Ninety-five multiple myeloma patients from our center and 95 volunteers as a control group were included in our study. The patients did not have any symptoms when stool samples were taken. For B.hominis, three consecutive stool samples were examined by saline-lugol trichrome staining and formalin-ethyl acetate concentration. Data were recorded and analyzed using SPSS 25.0.
Results
Patients with newly diagnosed multiple myeloma and any of the patients in the control group did not have any parasites other than B.hominis. A significant difference was found between the newly diagnosed MM patients and the control group in terms of the number of B.hominis occurrences in the stool (p <0.001).
Conclusions
According to this result, parasite load in stool increased in patients with MM. This result may reflect the suppression of the immune system of patients with MM. Accordingly, B.hominis should be considered as a causative agent in the presence of gastrointestinal symptoms that may occur during treatment in patients with MM.

Anahtar Kelimeler

Multiple myeloma, parasites, blastocystis hominis

Etik Beyan

Dear Editor, Our unique article, THE PREVALENCE OF BLASTOCYSTIS HOMINIS AND GASTROINTESTINAL SYSTEM PARASITES IN PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA DIAGNOSIS, has never been peer-reviewed or published elsewhere. All authors have read and approved the article. There are no conflicts of interest in this article, thus nothing to disclose. In this work, we aimed to elevate the parasite burden in multiple myeloma patients. We concentrated on Blastocystis hominis because it was the only parasite found in these patients. We wanted to learn more about the causes of gastrointestinal problems that multiple myeloma patients may have, so we conducted this study to do just that. Many thanks for your concern Dr. Cem SELİM Corresponding Author

Destekleyen Kurum

none

Kaynakça

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