Sedoanaljezi Altında Girişimsel İşlem Uygulanacak Hastalarda Menstrüel Siklusun İşlem Öncesi Anksiyete Üzerine Etkisi

Yıl 2025, Cilt: 35 Sayı: 3, 530 - 534, 30.06.2025

Emine Aslanlar , Mehmet Selçuk Uluer , Mehmet Sargın , Faruk Çiçekci

https://doi.org/10.54005/geneltip.1525625

Öz

Amaç: Adet döngüsünün ana hormonları olan östradiol ve progesteron, anksiyete ve korku düzenlemesinin nöral mekanizmaları üzerinde modüle edici etkilere sahiptir. Anksiyete, girişimsel tıbbi prosedürler uygulanan hastalarda yaygın bir sorundur. Bu nedenle girişimsel işlemler çoğunlukla sedasyon altında gerçekleştirilmektedir. Kadınlarda günlük yaşamdaki anksiyete düzeyinin menstrüel siklusun evrelerine bağlı olarak değiştiğini bildiren çalışmalar mevcuttur. Bu çalışmada, sedasyon uygulanacak hastalarda menstrüel siklusun girişimsel işlemle ilgili anksiyete düzeyine etkisini belirlemeyi amaçladık.
Gereç ve Yöntemler: Sedasyon altında girişimsel işlem yapılması planlanan 18-40 yaş arası, düzenli menstrüel siklusları olan (23-35 günde bir siklus) ASA I-II kadın hastalar çalışmaya dahil edilmiştir. Hastalara son adet dönemleri sorulmuş ve adet döngüsünün 1-10. günlerinde olanlar foliküler faz, 18-24. günlerinde olanlar ise luteal faz olarak gruplandırılmıştır. Anksiyete düzeyleri, State–Trait Anxiety Inventory (STAI-X1) ile değerlendirilmiş ve foliküler ve luteal fazdaki hastaların STAI –X1 skorları karşılaştırılmıştır.
Bulgular: Çalışma 86 hasta ile tamamlanmıştır. Elli sekiz hasta foliküler fazda ve 28 hasta luteal fazdadır. Kadınların ortalama siklus sıklığı foliküler fazda 27.93 ± 3.30 gün ve luteal fazda 27.29 ± 3.15 gün olup iki grup arasında anlamlı bir fark yoktu (p= 0.39). Foliküler fazda olanların STAI-X1 skoru 44.81 iken, luteal fazda olanların skoru 40.71 idi ve iki grup arasında anlamlı bir fark bulunamadı (p= 0.11). Sedoanaljezide kullanılan anestezik ilaç dozları iki grup arasında benzerdi (p= 0.96).
Sonuçlar: Menstrüel siklusun foliküler ve luteal evrelerindeki hastaların işlem öncesi anksiyete düzeyleri benzerdir.

Anahtar Kelimeler

Foliküler faz , işlem öncesi anksiyete , luteal faz , menstrüel döngü , sedoanaljezi

The Effect of Menstrual Cycle on Preprocedural Anxiety in Patients Undergoing Interventional Procedures Under Sedoanalgesia

Öz

Abstract
Aim: Estradiol and progesterone, the main hormones of the menstrual cycle, have modulating effects on neural mechanisms of anxiety and fear regulation. Anxiety is a common problem in patients undergoing interventional medical procedures. Therefore, interventional procedures are mostly performed under sedation. There are studies reporting that the level of anxiety in daily life varies in women depending on the phases of the menstrual cycle. In this study, we aimed to determine the effect of menstrual cycle on the level of anxiety related to the interventional procedure in patients to be sedated.
Methods: ASA I- II female patients between the ages of 18-40, with regular menstrual cycles (one cycle every 23-35 days), who were planned to undergo interventional procedures under sedation, were included in the study. Patients were asked about their last menstrual period, and those on the 1-10th day of the menstrual cycle were grouped as the follicular phase, and those on the 18-24th day were grouped as the luteal phase. Anxiety levels were assessed with the State-Trait Anxiety Inventory (STAI-X1) and compared between follicular and luteal phase patients.
Results: The study was completed with 86 patients. Fifty-eight patients were in the follicular phase and 28 in the luteal phase. The mean cycle frequency of women was 27.93 ± 3.30 days in the follicular phase and 27.29 ± 3.15 days in the luteal phase with no significant difference between the two groups (p= 0.39). While the STAI-X1 score of those in the follicular phase was 44.81, the score of those in the luteal phase was 40.71 and no significant difference was found between the two groups (p= 0.11). Anesthetic drug doses used in sedoanalgesia were similar between the two groups (p= 0.96).
Conclusion: Patients in the follicular and luteal phases of the menstrual cycle have similar levels of pre-procedural anxiety.

Anahtar Kelimeler

Menstrual Cycle , Follicular phase , Luteal phase , Preprocedural Anxiety , Sedoanalgesia

Etik Beyan

Ethics committee approval of the study was obtained from Selçuk University Faculty Of Medicine Local Ethics Committee (Approval no: 2020/528).

Kaynakça

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