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Uluslararası Sağlık Tüzüğü Temel Kapasitesi ile Bulaşıcı Hastalıklara Bağlı Ölüm Oranları Arasında Evrensel Sağlık Kapsamının Aracılık Rolü

Yıl 2025, Cilt: 35 Sayı: 3, 544 - 553, 30.06.2025
https://doi.org/10.54005/geneltip.1623431

Öz

Amaç: Bulaşıcı hastalıklar toplum sağlığı ve sürdürülebilir kalkınma çabaları üzerinde önemli bir tehdit olmaya devam etmektedir. Bulaşıcı hastalıklarla mücadele amacıyla sürdürülebilir kalkınma hedefleri kapsamında sağlık hizmeti kapasitesinin oluşturulması ve evrensel sağlık kapsamının sağlanması için hedefler belirlenmiştir. Sağlık hizmetinin fiziki ve teknik kapasitesinin iyileşmesi ve hizmete erişimin sağlanmasıyla bulaşıcı hastalıklarla mücadele edilmesi amaçlanmaktadır. Çalışmanın temel amacı International Health Regulations (IHR) hizmet kapsamının bulaşıcı hastalıklar bağlı ölüm oranları üzerindeki etkisinde Universal Health Coverage (UHC) hizmet kapsamının aracılık rolünün belirlenmesidir.
Gereç ve Yöntem: Çalışma kapsamında örneklem seçimi yapılmayıp IHR’ye taraf olan Dünya Sağlık Örgütüne üye 183 ülkenin 2021 yılına ait verileri kullanılmıştır. Çalışmanın amacı doğrultusunda basit aracılık modeli oluşturulmuştur. Değişkenler arasındaki ilişkiyi test eden aracılık etkisi analizi varsayımları regresyon analizleriyle test edilmiştir.
Bulgular: IHR temel kapasitesi ile bulaşıcı hastalıklara bağlı ölüm oranı arasında anlamlı negatif etki tespit edilmiştir. IHR temel kapasitesi ile UHC hizmet kapsamı arasında ise anlamlı pozitif etki olduğu belirlenmiştir. IHR ve UHC’nin birlikte dahil edildiği modelde UHC hizmet kapsamı ile bulaşıcı hastalıklara bağlı ölüm oranı arasında anlamlı negatif etki tespit edilmiştir. Aracılık etkisi analizi sonucunda ise IHR hizmet kapsamının bulaşıcı hastalıklara bağlı ölüm oranı üzerindeki etkisinde UHC hizmet kapsamının tam aracı rolü oynadığı belirlenmiştir.
Sonuç: Belirlenen bulgulara göre IHR temel kapasitesinin sağlık hizmetlerine erişim olmadan bulaşıcı hastalıklara bağlı ölüm oranı üzerinde sınırlı etkisinin olduğu söylenebilir. IHR temel kapasitelerinin toplumun sağlık hizmetine erişimiyle desteklenmesi gerekmektedir. Ülkelerin bulaşıcı hastalıklarla mücadelede IHR temel kapasitelerini arttırmaya yönelik çabalara devam etmesi ve bu çabaların UHC politikalarıyla entegre edilmesi önerilmektedir.

Kaynakça

  • 1. Jones KE, Patel NG, Levy MA, et al. Global trends in emerging infectious diseases. Nature. 2008;451:990-993.
  • 2. Tulchinsky TH, Varavikova EA. Communicable diseases. The New Public Health. 2014:149-236.
  • 3. Anser MK, Islam T, Khan MA, Zaman K, Nassani AA, Askar SE, et al. Identifying the potential causes, consequences, and prevention of communicable diseases (including COVID-19). Biomed Res Int. 2020;2020:1-13.
  • 4. World Health Organization (WHO). Communicable and noncommunicable diseases, and mental health. Accessed October 7, 2024. https://www.who.int/our-work/communicable-and-noncommunicable-diseases-and-mental-health
  • 5. United Nations. Sustainable development. Accessed November 8, 2024. https://sdgs.un.org/goals/goal3#targets_and_indicators
  • 6. World Health Organization (WHO). UHC service coverage index (3.8.1). Accessed November 9, 2024. https://www.who.int/data/gho/indicator-metadata-registry/imr-details/4834
  • 7. Ikeda N, Saito E, Kondo N, Inoue M, Ikede S, Satoh T, et al. What has made the population of Japan healthy? Lancet. 2011;378(9796):1094-1105.
  • 8. Moreno-Serra R, Smith PC. Does progress towards universal health coverage improve population health? Lancet. 2012;380(9845):917-923.
  • 9. Hajjar K, Lillo L, Martinez DA, Hermosilla M, Risko N. Association between universal health coverage and the disease burden of acute illness and injury at the global level. BMC Public Health. 2023;23:735.
  • 10. Kruk ME, Gage DA, Joseph NT, Danaei G, Garcia-Saiso S, Salomon JA. Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries. Lancet. 2018;382(10160):2203-2212.
  • 11. Konca M. The effect of universal health coverage on health outcomes: the case of Türkiye. Alanya Academic Review-Journal. 2024;8(2):490-502.
  • 12. Moon D, Jeon J, Park J, Choi MH, Kim MH, Choi H. Universal health coverage saves more lives among severely ill COVID-19 patients: a difference-in-differences analysis of individual patient data South Korea. Health Res Policy Sys. 2024;22:1-12.
  • 13. Kieny MP, Bekedam H, Dovlo D, Fitzgerald J, Habicht J, Harrison G, et al. Strengthening health systems for universal health coverage and sustainable development. Bull World Health Organ. 2017;85(7):537-539.
  • 14. Tsai FJ, Tipayamongkholgul M. Are countries’ self-reported assessments of their capacity for infectious disease control reliable? Associations among countries’ self-reported international health regulations 2005 capacity assessments and infectious disease control outcomes. BMC Public Health. 2020;20(282):1-9.
  • 15. Tsai FJ, Lin CP, Turbat B. Exploring association between countries’ self-reported international health regulations core capacity and COVID-19 control outcomes. J Glob Health Rep. 2021;5:e2021017.
  • 16. Wong MCS, Huang J, Wong SH, Teoh JYC. The potential effectiveness of the WHO international health regulations capacity requirements on control of the COVID-19 pandemic: a cross-sectional study of 114 countries. J R Soc Med. 2021;114(3):121-131.
  • 17. Satria FB, Tsai FJ, Turbat B. Analyzing self-evaluation capacity scores related to infectious disease control in international health regulations during the first year of the COVID-19 pandemic. Sci Rep. 2022;12:1-8.
  • 18. Duong DB, King AJ, Grépin KA, Hsu LY, Lim JF, Phillips C, et al. Strengthening national capacities for pandemic preparedness: a cross-country analysis of COVID-19 cases and deaths. Health Policy Plan. 2022;37(1):55-64.
  • 19. Wamala JF, Okot C, Makumbi I, Natseri N, Kisakye A, Nanyunja M, et al. Assessment of core capacities for the International Health Regulations (IHR[2005]) – Uganda, 2009. BMC Public Health. 2010;10(Suppl 1):1-9.
  • 20. Liu B, Sun Y, Dong Q, Zhang Z, Zhang L. Strengthening core public health capacity based on the implementation of the international health regulations (IHR) (2005): Chinese lessons. Int J Health Policy. 2015;4(6):381-386.
  • 21. Kandel N, Chungong S, Omaar A, Xing J. Health security capacities in the context of COVID-19 outbreak: an analysis of international health regulations annual report data from 182 countries. Lancet. 2020;395(10229):1047-1053.
  • 22. Gostin LO, Katz R. The international health regulations: the governing framework for global health security. Milbank Q. 2016;94(2):264-313.
  • 23. Fukuda-Parr S. When indicators fail: SPAR, the invisible measure of pandemic preparedness. Policy and Society. 2022;41(4):528-540. doi:10.1093/polsoc/puac024
  • 24. Kluge H, Martin-Moreno JM, Emiroglu N, Rodier G, Kelley E, Vujnovic M, et al. Strengthening global health security by embedding the international health regulations requirements into national health systems. BMJ Glob Health. 2018;3(1):1-7.
  • 25. Assefa Y, Hill PS, Gilks CF, Damme WV, van de Pas R, Woldeyohannes S, et al. Global health security and universal health coverage: understanding convergences and divergences for a synergistic response. PLoS One. 2020;15(12):1-16.
  • 26. Lee Y, Kim S, Oh J, Lee S. An ecological study on the association between international health regulations (IHR) core capacity scores and the universal health coverage (UHC) service coverage index. Global Health. 2022;18:1-13. 27. World Health Organization (WHO). IHR Score per capacity. Accessed September 3, 2024. https://extranet.who.int/e-spar/Home/CapacityScoreDetails
  • 28. World Health Organization (WHO). The Global Health Observatory. Accessed September 3, 2024. https://www.who.int/data/gho/data/indicators/indicator-details/GHO/uhc-index-of-service-coverage
  • 29. Institute for Health Metrics and Evaluation (IHME). Global burden of disease (GBD) results. Accessed September 3, 2024. https://vizhub.healthdata.org/gbd-results/
  • 30. World Health Organization (WHO). Electronic IHR states parties self-assessment annual reporting tool. Accessed March 20, 2025. https://extranet.who.int/e-spar/#background
  • 31. George D, Mallery M. SPSS for Windows Step by Step: A Simple Guide and Reference. 17.0 update. Boston, MA: Pearson; 2010.
  • 32. Tabachnick BG, Fidell LS. Using Multivariate Statistics. 7th ed. New York, NY: Pearson; 2019.
  • 33. Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. 2nd ed. New York, NY: The Guilford Press; 2018.
  • 34. Wu AD, Zumbo BD. Understanding and using mediators and moderators. Soc Indic Res. 2008;87:367-392.
  • 35. Chan M, Hu P, Mak MKF. Mediation analysis and warranted inferences in media and communication research: examining research design in communication journals from 1996 to 2017. Journal Mass Commun Q. 2022;99(2):463-486.
  • 36. Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986;51(6):1173-1182.
  • 37. Doble A, Sheridan Z, Razavi A, Wilson A, Okereke E. The role of international support programs in global health security capacity building: a scoping review. PLOS Glob Public Health. 2023;3(4):1-21.
  • 38. Saengtabtim K, Tang J, Leelawat N, Egawa S, Suppasri A, Imamura F. Universal health coverage mitigated COVID-19 health-related consequences in Asia Oceania. Int J Disaster Risk Reduct. 2023;92:1-15.
  • 39. Hogan DR, Stevens GA, Hosseinpoor AR, Boerma T. Monitoring universal health coverage within the sustainable development goals: development and baseline data for an index of essential health services. Lancet Glob Health. 2018;6(2):e152-e168.
  • 40. Gaffney AE, Hawks L, Bor DH, Wollhandler S, Himmelstein DU, McCormick D. 18.2 million individuals at increased risk of severe COVID-19 illness are un- or underinsured. J Gen Intern Med. 2020;35:2487-2489.
  • 41. Frenk J, de Ferranti D. Universal health coverage: good health, good economics. Lancet. 2012;330(9845):862-864.
  • 42. O’Connell T, Rasanathan K, Chopra M. What does universal health coverage mean? Lancet. 2014;383(9913):277-279.
  • 43. Shoman H, Karafillakis E, Rawaf S. The link between the West African Ebola outbreak and health systems in Guinea, Liberia, and Sierra Leone: a systematic review. Global Health. 2017;13(1):1-22.
  • 44. Goenka A, Liu L. Infectious diseases, human capital and economic growth. Econ Theory. 2020;70:1-47.
  • 45. Wagstaff A, Neelsen S. A comprehensive assessment of universal health coverage in 111 countries: a retrospective observational study. Lancet Glob Health. 2020;8(1):39-49.
  • 46. Agustina R, Dartanto T, Sitompul R, Susiloretni KA, Suparmi MKM, Achadi EL, et al. Universal health coverage in Indonesia: concept, progress, and challenges. Lancet. 2019;393(10166):75-102.

The Mediating Role of Universal Health Coverage Between International Health Regulations Core Capacities and Mortality from Communicable Diseases

Yıl 2025, Cilt: 35 Sayı: 3, 544 - 553, 30.06.2025
https://doi.org/10.54005/geneltip.1623431

Öz

Aim: Communicable diseases continue to pose a significant threat to public health and sustainable development efforts. To address this challenge, targets under the Sustainable Development Goals focus on enhancing healthcare capacity and achieving Universal Health Coverage (UHC). Improving the physical and technical capacity of healthcare services and ensuring access aim to support the fight against communicable diseases. This study aims to determine the mediating role of Universal Health Coverage (UHC) service coverage in the relationship between International Health Regulations (IHR) core capacities and mortality rates due to communicable diseases.
Materials and Methods: The study utilized 2021 data from 183 World Health Organization member states that are party to the IHR, without sample selection. A simple mediation model was developed, and assumptions of mediation effect analysis were tested through regression analyses to evaluate relationships between variables.
Results: A significant negative effect was observed between IHR core capacities and mortality rates due to communicable diseases. Additionally, a significant positive effect was identified between IHR core capacities and UHC service coverage. In the model incorporating both IHR and UHC, a significant negative effect was observed between UHC service coverage and mortality rates due to communicable diseases. Mediation analysis revealed that UHC service coverage fully mediates the effect of IHR core capacities on mortality rates due to communicable diseases.
Conclusion: The findings suggest that IHR core capacities alone have a limited effect on reducing mortality rates without adequate healthcare access. Supporting IHR core capacities with improved access to healthcare is essential. Countries should continue efforts to enhance IHR core capacities and integrate these efforts with UHC policies to effectively combat communicable diseases.

Etik Beyan

Ethical approval was not required as the data included in the study and analyzed were obtained from open data sources.

Kaynakça

  • 1. Jones KE, Patel NG, Levy MA, et al. Global trends in emerging infectious diseases. Nature. 2008;451:990-993.
  • 2. Tulchinsky TH, Varavikova EA. Communicable diseases. The New Public Health. 2014:149-236.
  • 3. Anser MK, Islam T, Khan MA, Zaman K, Nassani AA, Askar SE, et al. Identifying the potential causes, consequences, and prevention of communicable diseases (including COVID-19). Biomed Res Int. 2020;2020:1-13.
  • 4. World Health Organization (WHO). Communicable and noncommunicable diseases, and mental health. Accessed October 7, 2024. https://www.who.int/our-work/communicable-and-noncommunicable-diseases-and-mental-health
  • 5. United Nations. Sustainable development. Accessed November 8, 2024. https://sdgs.un.org/goals/goal3#targets_and_indicators
  • 6. World Health Organization (WHO). UHC service coverage index (3.8.1). Accessed November 9, 2024. https://www.who.int/data/gho/indicator-metadata-registry/imr-details/4834
  • 7. Ikeda N, Saito E, Kondo N, Inoue M, Ikede S, Satoh T, et al. What has made the population of Japan healthy? Lancet. 2011;378(9796):1094-1105.
  • 8. Moreno-Serra R, Smith PC. Does progress towards universal health coverage improve population health? Lancet. 2012;380(9845):917-923.
  • 9. Hajjar K, Lillo L, Martinez DA, Hermosilla M, Risko N. Association between universal health coverage and the disease burden of acute illness and injury at the global level. BMC Public Health. 2023;23:735.
  • 10. Kruk ME, Gage DA, Joseph NT, Danaei G, Garcia-Saiso S, Salomon JA. Mortality due to low-quality health systems in the universal health coverage era: a systematic analysis of amenable deaths in 137 countries. Lancet. 2018;382(10160):2203-2212.
  • 11. Konca M. The effect of universal health coverage on health outcomes: the case of Türkiye. Alanya Academic Review-Journal. 2024;8(2):490-502.
  • 12. Moon D, Jeon J, Park J, Choi MH, Kim MH, Choi H. Universal health coverage saves more lives among severely ill COVID-19 patients: a difference-in-differences analysis of individual patient data South Korea. Health Res Policy Sys. 2024;22:1-12.
  • 13. Kieny MP, Bekedam H, Dovlo D, Fitzgerald J, Habicht J, Harrison G, et al. Strengthening health systems for universal health coverage and sustainable development. Bull World Health Organ. 2017;85(7):537-539.
  • 14. Tsai FJ, Tipayamongkholgul M. Are countries’ self-reported assessments of their capacity for infectious disease control reliable? Associations among countries’ self-reported international health regulations 2005 capacity assessments and infectious disease control outcomes. BMC Public Health. 2020;20(282):1-9.
  • 15. Tsai FJ, Lin CP, Turbat B. Exploring association between countries’ self-reported international health regulations core capacity and COVID-19 control outcomes. J Glob Health Rep. 2021;5:e2021017.
  • 16. Wong MCS, Huang J, Wong SH, Teoh JYC. The potential effectiveness of the WHO international health regulations capacity requirements on control of the COVID-19 pandemic: a cross-sectional study of 114 countries. J R Soc Med. 2021;114(3):121-131.
  • 17. Satria FB, Tsai FJ, Turbat B. Analyzing self-evaluation capacity scores related to infectious disease control in international health regulations during the first year of the COVID-19 pandemic. Sci Rep. 2022;12:1-8.
  • 18. Duong DB, King AJ, Grépin KA, Hsu LY, Lim JF, Phillips C, et al. Strengthening national capacities for pandemic preparedness: a cross-country analysis of COVID-19 cases and deaths. Health Policy Plan. 2022;37(1):55-64.
  • 19. Wamala JF, Okot C, Makumbi I, Natseri N, Kisakye A, Nanyunja M, et al. Assessment of core capacities for the International Health Regulations (IHR[2005]) – Uganda, 2009. BMC Public Health. 2010;10(Suppl 1):1-9.
  • 20. Liu B, Sun Y, Dong Q, Zhang Z, Zhang L. Strengthening core public health capacity based on the implementation of the international health regulations (IHR) (2005): Chinese lessons. Int J Health Policy. 2015;4(6):381-386.
  • 21. Kandel N, Chungong S, Omaar A, Xing J. Health security capacities in the context of COVID-19 outbreak: an analysis of international health regulations annual report data from 182 countries. Lancet. 2020;395(10229):1047-1053.
  • 22. Gostin LO, Katz R. The international health regulations: the governing framework for global health security. Milbank Q. 2016;94(2):264-313.
  • 23. Fukuda-Parr S. When indicators fail: SPAR, the invisible measure of pandemic preparedness. Policy and Society. 2022;41(4):528-540. doi:10.1093/polsoc/puac024
  • 24. Kluge H, Martin-Moreno JM, Emiroglu N, Rodier G, Kelley E, Vujnovic M, et al. Strengthening global health security by embedding the international health regulations requirements into national health systems. BMJ Glob Health. 2018;3(1):1-7.
  • 25. Assefa Y, Hill PS, Gilks CF, Damme WV, van de Pas R, Woldeyohannes S, et al. Global health security and universal health coverage: understanding convergences and divergences for a synergistic response. PLoS One. 2020;15(12):1-16.
  • 26. Lee Y, Kim S, Oh J, Lee S. An ecological study on the association between international health regulations (IHR) core capacity scores and the universal health coverage (UHC) service coverage index. Global Health. 2022;18:1-13. 27. World Health Organization (WHO). IHR Score per capacity. Accessed September 3, 2024. https://extranet.who.int/e-spar/Home/CapacityScoreDetails
  • 28. World Health Organization (WHO). The Global Health Observatory. Accessed September 3, 2024. https://www.who.int/data/gho/data/indicators/indicator-details/GHO/uhc-index-of-service-coverage
  • 29. Institute for Health Metrics and Evaluation (IHME). Global burden of disease (GBD) results. Accessed September 3, 2024. https://vizhub.healthdata.org/gbd-results/
  • 30. World Health Organization (WHO). Electronic IHR states parties self-assessment annual reporting tool. Accessed March 20, 2025. https://extranet.who.int/e-spar/#background
  • 31. George D, Mallery M. SPSS for Windows Step by Step: A Simple Guide and Reference. 17.0 update. Boston, MA: Pearson; 2010.
  • 32. Tabachnick BG, Fidell LS. Using Multivariate Statistics. 7th ed. New York, NY: Pearson; 2019.
  • 33. Hayes AF. Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. 2nd ed. New York, NY: The Guilford Press; 2018.
  • 34. Wu AD, Zumbo BD. Understanding and using mediators and moderators. Soc Indic Res. 2008;87:367-392.
  • 35. Chan M, Hu P, Mak MKF. Mediation analysis and warranted inferences in media and communication research: examining research design in communication journals from 1996 to 2017. Journal Mass Commun Q. 2022;99(2):463-486.
  • 36. Baron RM, Kenny DA. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol. 1986;51(6):1173-1182.
  • 37. Doble A, Sheridan Z, Razavi A, Wilson A, Okereke E. The role of international support programs in global health security capacity building: a scoping review. PLOS Glob Public Health. 2023;3(4):1-21.
  • 38. Saengtabtim K, Tang J, Leelawat N, Egawa S, Suppasri A, Imamura F. Universal health coverage mitigated COVID-19 health-related consequences in Asia Oceania. Int J Disaster Risk Reduct. 2023;92:1-15.
  • 39. Hogan DR, Stevens GA, Hosseinpoor AR, Boerma T. Monitoring universal health coverage within the sustainable development goals: development and baseline data for an index of essential health services. Lancet Glob Health. 2018;6(2):e152-e168.
  • 40. Gaffney AE, Hawks L, Bor DH, Wollhandler S, Himmelstein DU, McCormick D. 18.2 million individuals at increased risk of severe COVID-19 illness are un- or underinsured. J Gen Intern Med. 2020;35:2487-2489.
  • 41. Frenk J, de Ferranti D. Universal health coverage: good health, good economics. Lancet. 2012;330(9845):862-864.
  • 42. O’Connell T, Rasanathan K, Chopra M. What does universal health coverage mean? Lancet. 2014;383(9913):277-279.
  • 43. Shoman H, Karafillakis E, Rawaf S. The link between the West African Ebola outbreak and health systems in Guinea, Liberia, and Sierra Leone: a systematic review. Global Health. 2017;13(1):1-22.
  • 44. Goenka A, Liu L. Infectious diseases, human capital and economic growth. Econ Theory. 2020;70:1-47.
  • 45. Wagstaff A, Neelsen S. A comprehensive assessment of universal health coverage in 111 countries: a retrospective observational study. Lancet Glob Health. 2020;8(1):39-49.
  • 46. Agustina R, Dartanto T, Sitompul R, Susiloretni KA, Suparmi MKM, Achadi EL, et al. Universal health coverage in Indonesia: concept, progress, and challenges. Lancet. 2019;393(10166):75-102.
Toplam 45 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Bulaşıcı Hastalıklar, Klinik Tıp Bilimleri (Diğer)
Bölüm Original Article
Yazarlar

Deniz Tugay Arslan 0000-0002-9654-2263

Yayımlanma Tarihi 30 Haziran 2025
Gönderilme Tarihi 20 Ocak 2025
Kabul Tarihi 9 Mayıs 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 35 Sayı: 3

Kaynak Göster

Vancouver Arslan DT. The Mediating Role of Universal Health Coverage Between International Health Regulations Core Capacities and Mortality from Communicable Diseases. Genel Tıp Derg. 2025;35(3):544-53.