Isolated Laryngeal Involvement in Mucosal Membrane Pemphigoid: Diagnostic and Surgical Treatment Approach

Yıl 2025, Cilt: 35 Sayı: 5, 1041 - 1045, 28.10.2025

Bülent Ulusoy , Hürü Beyza Cerit , Gülcan Saylam Kurtipek

https://doi.org/10.54005/geneltip.1771684

Öz

Mucous membrane pemphigoid (MMP) is a chronic autoimmune subepithelial blistering disorder that primarily affects mucosal surfaces. Laryngeal involvement is uncommon but clinically important, as it may result in progressive scarring and severe airway obstruction. Because of its rarity, the diagnosis can be easily overlooked, and the number of reported cases in the literature remains limited. In this case report, we present the clinical findings, diagnostic approach, treatment strategy, and follow-up of a patient with laryngeal MMP. By sharing this case, we aim to contribute to the limited body of evidence on this rare presentation and highlight the importance of early recognition and appropriate management in preventing life-threatening complications.

Anahtar Kelimeler

Pemphigoid , Autoimmune Diseases , Laryngeal Mucosa , Lasers

Mukozal Membran Pemfigoidinde İzole Larenks Tutulumu: Tanısal ve Cerrahi Tedavi Yaklaşımı

Öz

Mukoza zarı pemfigoidi (MMP), öncelikli olarak mukozal yüzeyleri etkileyen kronik bir otoimmün subepitelyal büllöz hastalıktır. Larenks tutulumu nadirdir, ancak klinik açıdan önemlidir, çünkü ilerleyici skarlaşma ve ciddi hava yolu tıkanıklığına neden olabilir. Nadir görülmesi nedeniyle tanı kolayca gözden kaçabilir ve literatürde bildirilen vaka sayısı sınırlıdır. Bu olgu sunumunda, larengeal MMP'li bir hastanın klinik bulgularını, tanı yaklaşımını, tedavi stratejisini ve takibini sunuyoruz. Bu vakayı paylaşarak, bu nadir tabloya ilişkin sınırlı sayıdaki kanıta katkıda bulunmayı ve yaşamı tehdit eden komplikasyonları önlemede erken tanı ve uygun tedavinin önemini vurgulamayı amaçlıyoruz.

Anahtar Kelimeler

Pemfigus , Otoimmün Hastalıklar , Laryngeal Mukoza , Lazer

Kaynakça

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