BAZI YENİLEBİLİR ASTERACEAE ÜYELERİNİN ANTİMİKROBİYAL, ANTİBİYOFİLM, ANTİ-QUORUM SENSİNG VE ANTİOKSİDAN AKTİVİTELERİ

Öz

Bu çalışmada, S. oleraceus, T. scaturiginosum, T. bithynicum ve L. tuberosus’un antimikrobiyal, antioksidan ve anti-quorum sensing aktivitesi araştırılmıştır. T. scaturiginosum ve T. bithynicum antimikrobiyal aktivite açısından etkili bulunmuştur. En yüksek antibiyofilm inhibisyonunu P. aeruginosa ATCC 27853 üzerinde S. oleraceus’un %33.30’luk sulu ekstraktı göstermiştir. S. oleraceus sulu ekstraktı %35.32 viyolasin inhibisyonu gösterirken, T. bithynicum quorum sensing inhibisyonu için 13 mm’lik zon çapı göstermiştir. L. tuberosus etanol ekstraktı, %52.5 anti-swarming aktivitesi ile dikkat çekici bulunmuştur. Antioksidan aktivite açısından en etkili bitki L. tuberosus olarak tespit edilmiştir. Bu değer DPPH için 4.36 mg/mL IC50 ve FTC aktivitesi için %67.64’tür. Elde edilen bulgular yenilebilir bitkilerin mikroorganizma direncinin azaltılması ve hastalıkların tedavisinde kullanılması için uygun adaylar olabileceği göstermiştir.

Anahtar Kelimeler

• Antimikrobiyal
• antibiyofilm
• anti-quorum sensing
• antioksidan
• yenilebilir bitkiler

ANTIMICROBIAL, ANTIBIOFILM, ANTI-QUORUM SENSING AND ANTIOXIDANT ACTIVITIES OF SOME EDIBLE ASTERACEAE MEMBERS

Öz

In this study, antimicrobial, antioxidant and anti-quorum sensing activities of S. oleraceus, T. scaturiginosum, T. bithynicum and L. tuberosus were investigated. T. scaturiginosum and T. bithynicum were effective in terms of antimicrobial activity. The highest antibiofilm inhibition was shown by 33.30% aqueous extract of S. oleraceus on P. aeruginosa ATCC 27853. While S. oleraceus aqueous extract showed 35.32% violacein inhibition, T. bithynicum had a zone diameter of 13 mm for quorum sensing inhibition. L. tuberosus ethanol extract was found remarkable with its 52.5% anti-swarming activity. The most effective plant in terms of antioxidant activity was determined as L. tuberosus. This value is IC50 4.36 mg/mL for DPPH and 67.64% for FTC activity. It has been shown that these edible plants may be suitable candidates for reducing microorganismal resistance and using them in the treatment of diseases.

Anahtar Kelimeler

• Antimicrobial
• antibiofilm
• antiquorum sensing
• antioxidant
• edible plants

Kaynakça

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