Erzurum İli Huzursuz Bacak Sendromu Prevelansının Araştırılması ve Sosyodemografik Özelliklerin İncelenmesi

Öz

Giriş: HBS epidemiyoloji çalışmalarında %0.9-10 gibi farklı prevelans oranları bildirilmiştir. HBS hastalarında cinsiyet, yaş, genetik yatkınlık, anemi, hipertansiyon, diyabet, hiperkolesterolemi, depresif bozukluk, tiroid, akciğer ve böbrek hastalıkları gibi eşlik eden komorbid durumlarla ilişkisi araştırılmış ve bazı yerleşkelerde bu özellikler için farklı sonuçlar bildirilmiştir. Çalışmamızda, Erzurum ili HBS prevelansını, sosyodemografik özelliklerini ve komorbid durumlar ile ilişkisini incelemeyi amaçladık.

Gereç-Yöntem: Bu çalışma, Atatürk Üniversitesi Tıp Fakültesi Nöroepidemiyoloji Çalışma Grubu tarafından Sağlık müdürlüğüne bağlı olan aile hekimlerinin nüfus kayıtları kullanılarak, kapı kapı gezilerek yapıldı. Her bireyin sosyodemografik özelliklerini ve HBS’ yi belirlemek için iki farklı anket uygulandı. HBS tespit edilen hastalara IRLSSGRS anketi uygulandı. Hastalığın prevalans oranı, yaşa, cinsiyete göre dağılımı ve ilişkili durumlar araştırıldı. İstatistiksel değerlendirmede p≤0.05’ ten küçük olan durumlar anlamlı kabul edildi.

Bulgular: 4093 birey değerlendirildi ve 282 (%6.9) HBS’ li olgu tespit edildi. Olguların yaş cinsiyet, sosyodemografik özellikleri ve komorbid durumlar ile ilişkisi araştırıldı (Tablo I). HBS ile komorbid durumların arasında ilişki incelendiğinde tiroid hastalığı haricinde diğer durumlarla HBS arasında anlamlı istatistiksel fark tespit edildi (Tablo I). Vakaların %34.4’ ünde en az bir akrabasında benzer şikâyetleri olduğu tespit edildi. Başlangıç yaşı ≤40 olan olguların oranı daha fazlaydı ve istatistiksel olarak anlamlı fark tespit edildi. HBS semptomlarının orta ve ciddi olduğu gruplarda olgu sayısı fazlaydı (Tablo II).

Sonuç: Çalışmamızda 15–80 yaş arası popülâsyonda HBS görülme sıklığını %6.9 tespit ettik. Vakaların yaş gruplarına göre dağılımlarında ise anlamlı farklılık yoktu. HBS ile cinsiyet arasında istatistiksel olarak anlamlı farklılık vardı (p=0.048). Eğitim, ekonomik durum ve meslek ile hastalık arasında ilişki yoktu. HBS’ in sigara ve alkol kullanımı ile ilişkisi yoktu ve komorbid durumlardan tiroid hastalığı haricinde sorgulanan diğer hastalıklarla HBS arasında anlamlı istatistiksel farklılık tespit ettik. Vakaların üçte birinde üst ekstremite tutulumu ve aile öyküsü pozitif olduğu görüldü. Vakaların yarısından fazlasında semptomlar 40 yaşından önce başlamıştı.Tespitlerimiz HBS’ nin sık görüldüğünü, yüksek rakımla sıklığının artabileceğini göstermesi açısından önemlidir.

Anahtar Kelimeler

• Huzursuz Bacak Sendromu,Prevalans,Demografik Faktörler

Investigation of Restless Leg Syndrome Prevalence and Assosiated Sociodemographic Features in Province of Erzurum

Öz

Abstract

Introduction: Prevalence of Restless leg syndrome (RLS) is reported between 0.9%-10% in epidemiologic studies. Associations of sex, age, genetic predisposition, anemia, hypertension, diabetes, hypercholesterolemia, depression disorders, thyroid disorders, lung and kidney diseases with RLS were researched and different results were found in different locations. In this study, we aim to investigate the prevalence, sociodemographic features and association of comorbid situations of RLS in the province of Erzurum.

Material and Methods: This study was conducted by face-to-face interviews performed by neuroepidemiology study group of Faculty of Medicine of Ataturk University using the records of family doctors abide by health directorate. Two different questionnaires were asked to each contributor to determine the sociodemographic status and RLS consecutively. IRLSSGRS survey was performed to contributors to whom RLS was detected. Prevalence, stratifications for sex and age along with comorbid situations were investigated. A p value lower than 0.05 was accepted as significant in statistical analyzes.

Results: Four thousand and ninety-three individuals were investigated and 282 (6.9%) patients with RLS were detected. Data belong to individuals regarding age, sex, sociodemographic features and comorbid situations were obtained (Table I). Regarding the association of comorbid situations, all investigated comorbid situations other than thyroid disorders were associated with RLS (Table I). At least one relative had similar symptoms in 34.4% of the patients. Cases were significantly more frequent under 40 years of age. Number of cases with mild and severe RLS symptoms were higher (Table II).

Discussion: In this study, we found the prevalence of RLS 6.9% in the population aged between 15–80 years. There was no statistically significant difference of distribution by means of age groups. There was statistically significant difference by means of gender distribution (p:0.048). There was no connection between disease and education status, economic status and occupation. RLS was not associated with smoking or alcohol consumption. RLS was associated with all investigated comorbid situations other than thyroid disorders. One third of the cases had upper extremity involvement and positive family history. More than half of the cases, symptoms started before the age of 40. Our findings were important in terms of high prevalence and increased disease frequency with high altitude.

Anahtar Kelimeler

• Restless Legs Syndrome,Prevalence,Demographic Factors

Kaynakça

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