2-Hidroksinaftaldehit Pentaflorofenil Hidrazon Bileşiğinin Sentezi, Karakterizasyonu ve Silico ADME Çalışmaları

Abstract

Bu çalışmada pentaflorofenil hidrazin ile 2-hidroksi-naftaldehit bileşiklerinin kondenzasyon tepkimesi sonucu 2-hidroksi-naftaldehit pentaflorofenilhidrazon Schiff bazı sentezlendi. Sentezlenen bileşiğin yapısı, 1H NMR, 13C NMR, 19F NMR, FT-IR ve elemental analiz yöntemleri ile karakterize edildi. Daha sonra, elde edilen bileşiğin ilaç olarak göstereceği aktivitenin belirlenmesi amacıyla ADME çalışması yapıldı.

Keywords

• Hidrazon bileşikleri
• Schiff bazı
• ADME

Kaynakça

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