Bridging Green Chemistry and Biomedicine: Biological Activity and Catalytic Efficacy of Polymer-Derived Nanoparticles

Öz

Green polymeric matrices, encompassing both natural biopolymers and biodegradable synthetic counterparts, have emerged as a pivotal platform in the advancement of sustainable nanotechnology, offering a versatile foundation for the engineering of high-performance nanomaterials. Leveraging their intrinsic biocompatibility, biodegradability, and superior surface area-to-volume ratios, this study investigates the biological functionalities of nanoparticles derived from these eco-friendly polymers, specifically targeting their antimicrobial and antioxidant efficacies, alongside their potential as targeted drug delivery vectors. Beyond biomedical domains, the research extends to the utilization of these biocompatible matrices within the realm of green chemistry. Herein, these polymers serve a dual role as eco-friendly stabilizers and, particularly in the case of polysaccharides, as intrinsic reducing agents in the synthesis of metallic nanoparticles (MNPs). These polymer-supported MNPs are subsequently evaluated as highly efficient, recyclable heterogeneous catalysts for diverse organic transformations, offering a more atom-economical and low-waste alternative to conventional catalytic protocols. Ultimately, by bridging therapeutic applications with green catalytic synthesis, this work establishes green polymer-based nanomaterials as a dual functional, sustainable platform for both medicinal and chemical sciences. 

Anahtar Kelimeler

• Green polymers
• Natural Polymers
• Nanoparticles
• Green Chemistry
• Catalytic and Biological Activities

Destekleyen Kurum

No

Etik Beyan

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Teşekkür

The authors would like to thank to Duzce University.

Yeşil Kimya ve Biyomedikal Arasındaki Köprü: Polimer Türevli Nanopartiküllerin Biyolojik Aktivitesi ve Katalitik Etkinliği

Öz

Hem doğal biyopolimerleri hem de biyolojik olarak parçalanabilir sentetik muadillerini kapsayan yeşil polimerik matrisler, sürdürülebilir nanoteknolojinin ilerlemesinde önemli bir platform olarak ortaya çıkmış ve yüksek performanslı nanomalzemelerin mühendisliği için çok yönlü bir temel sunmuştur. Bu çalışma, bu çevre dostu polimerlerden türetilen nanopartiküllerin biyolojik işlevlerini, özellikle antimikrobiyal ve antioksidan etkinliklerini ve hedeflenmiş ilaç dağıtım vektörleri olarak potansiyellerini hedefleyerek araştırmaktadır. Biyomedikal alanların ötesinde, araştırma bu biyolojik olarak uyumlu matrislerin yeşil kimya alanındaki kullanımına da uzanmaktadır. Burada, bu polimerler, özellikle polisakkaritler söz konusu olduğunda, metalik nanopartiküllerin (MNP'ler) sentezinde çevre dostu stabilizatörler ve doğal indirgeyici ajanlar olarak ikili bir rol oynamaktadır. Bu polimer destekli MNP'ler daha sonra çeşitli organik dönüşümler için son derece verimli, geri dönüştürülebilir heterojen katalizörler olarak değerlendirilmekte ve geleneksel katalitik protokollere göre daha atom ekonomisine dayalı ve düşük atık üreten bir alternatif sunmaktadır. Sonuç olarak, terapötik uygulamaları yeşil katalitik sentezle birleştirerek, bu çalışma yeşil polimer bazlı nanomalzemeleri hem tıp hem de kimya bilimleri için çift işlevli, sürdürülebilir bir platform olarak ortaya koymaktadır. 

Anahtar Kelimeler

• Yeşil polimerler
• Doğal Polimerler
• Nanoparçacıklar
• Yeşil Kimya
• Katalitik ve Biyolojik Aktiviteler

Destekleyen Kurum

Yok

Etik Beyan

Yazarlar, bu makalede bildirilen çalışmayı etkileyebilecek bilinen herhangi bir rekabet eden mali çıkarlarının veya kişisel ilişkilerinin olmadığını beyan etmektedirler.

Teşekkür

Yazarlar Düzce Üniversitesi'ne teşekkürlerini sunarlar.

Kaynakça

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