Stronsiyum Katkılı Biyocam ve Bakır Nanoparçacıklarından 3D Kompozit Yapı İskelesi Üretimi

Yıl 2018, Cilt: 6 Sayı: 3, 558 - 569, 30.09.2018

Ayşe Özyuğuran-arifoğlu

https://doi.org/10.29109/gujsc.386381

Cited By: 1

Öz

Bu çalışmada, çözücü
döküm ve tanecik uzaklaştırma yöntemi kullanılarak, çok işlevli yapı
iskelelerinin geliştirilmesi için ilgili iyonlarla BG / polimer 3D kompozit
yapı iskelelerinin üretilmesi amaçlanmıştır. Gözenekli yapıya sahip yapı
iskeleleri başarıyla sentezlenmiş ve yapı iskelelerinin mikroyapısında iyi bir
gözenek bağlantısının bulunduğu gözlemlenmiştir. Kompozit yapı iskelelerinin in
vitro biyoaktivitesi; Taramalı Elektron Mikroskopisi (SEM), X-ışını kırınımı ve
Fourier-Dönüşümlü Kızılötesi Spektroskopi ölçümleri ile teyit edilmiştir. Bunun
dışında, terapötik iyonların salınımının; SBF'de kalma sürelerinin bir
fonksiyonu olarak, stronsiyum ve bakır iyonları için sırasıyla 1.27-5.36 ppm ve
1.53-5.42 ppm aralığında değiştiği belirlenmiştir. Bu sonuç yapı iskelelerinin,
kemik dokusu rejenerasyonunun belirleyicisi olan SBF ortamına, stronsiyum ve
bakır dozlarının kontrollü olarak verebileceğini göstermiştir.

Anahtar Kelimeler

: Kompozit Yapı İskelesi, Biyoaktif Cam, Terapötik İyonlar

Kaynakça

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