Effects of Noninvasive Mechanical Ventilation in COVID-19 Patients

Yıl 2023, , 534 - 540, 18.06.2023

Yesim Yaman Aktaş , Neziha Karabulut , Sedanur Çatal , Hatice Oğuzhan

https://doi.org/10.37989/gumussagbil.1228533

Öz

The aim of this study was to examine the results of NIMV applied with a full face mask in COVID-19 patients. A descriptive and cross-sectional study. The study was conducted in the 1st level COVID-19 Intensive Care Unit of a university training and research hospital between August 15 and November 15, 2021. The study included 31 critical care patients who agreed to participate in the study and met the sampling criteria. The data was collected by the third researcher using the questionnaire based on the literature. The mean age of patients was 68.90±9.97 (41-82) years. In the measurements before NIMV, after the first application and after 24-h, a statistically significant difference was found between measurements in terms of SpO2 scores (p<0.001). In venous blood gas measurements before and 24-h after NIMV, a statistically significant difference was found between the measurements in terms of PCO2 scores (p<0.05). The study findings showed that NIMV was effective in terms of SpO2 and venous PCO2 scores in COVID-19 patients. It can be used as an effective option in the management of acute hypoxemic respiratory failure in COVID-19 patients.

Anahtar Kelimeler

COVID-19, noninvasive mechanical ventilation, critical care, patient

COVID-19 Hastalarında Noninvazif Mekanik Ventilasyonun Etkileri

Öz

Bu çalışmanın amacı, COVID-19 hastalarında tam yüz maskesi ile uygulanan NIMV sonuçlarının incelenmesidir. Tanımlayıcı ve kesitsel bir çalışmadır. Bu çalışma bir üniversite eğitim ve araştırma hastanesinin 1. basamak COVID-19 Yoğun Bakım Ünitesinde 15 Ağustos-15 Kasım 2021 tarihleri arasında yapıldı. Araştırmanın örneklemini araştırmaya katılmayı kabul eden ve örneklem kriterlerine uyan 31 yoğun bakım hastası oluşturdu. Veriler literatür doğrultusunda hazırlanan anket kullanılarak üçüncü araştırmacı tarafından toplandı. Bulgular: Hastaların yaş ortalaması 68.90±9.97 (41-82) idi. NIMV öncesi, ilk uygulama sonrası ve 24 saat sonra yapılan ölçümlerde SpO2 skorları açısından ölçümler arasında istatistiksel olarak anlamlı fark bulundu (p<0.001). NIMV öncesi ve 24 saat sonra venöz kan gazı ölçümlerinde PCO2 skorları açısından ölçümler arasında istatistiksel olarak anlamlı fark bulundu (p<0.05). Çalışma bulguları, NIMV'nin COVID-19 hastalarında SpO2 ve venöz PCO2 skorları açısından etkili olduğunu göstermiştir. COVID-19 hastalarında akut hipoksemik solunum yetmezliğinin tedavisinde etkili bir seçenek olarak kullanılabilir.

Anahtar Kelimeler

COVID-19, noninvazif mekanik ventilasyon, yoğun bakım, hasta

Kaynakça

• 1. Wu, Z., & McGoogan, J. M. (2020). Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA, 323(13), 1239-1242. https://doi.org/10.1001/jama.2020.2648
• 2. Rollas, K., & Şenoğlu, N. (2020). Management of Covid-19 patients ın ıntensive care unit. Tepecik Eğitim ve Araştırma Hastanesi Dergisi, 30, 142-55. https://doi.org/10.5222/terh.2020.77044
• 3. Turkish Ministry of Health General Directorate of Public Health COVID-19 (SARS-CoV-2 Infection) Guide (Scientific committee study), https://covid19bilgi.saglik.gov.tr [date of Access: 14 September 2022].
• 4. Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., ... & Cao, B. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet, 395(10229), 1054-1062. https://doi.org/10.1016/S0140-6736(20)30566-3
• 5. Turkish Internal and Surgical Intensive Care Association COVID-19 disease follow-up recommendations, https://www.dcyogunbakim.org.tr/tdcy-covid-19-hastaligi-follow-onerileri/ [date of Access: 14 September 2022].
• 6. Carter, C., Aedy, H., & Notter, J. (2020). COVID-19 disease: Non-Invasive Ventilation and high frequency nasal oxygenation. Clinics in Integrated Care, 1, 100006. https://doi.org/10.1016/j.intcar.2020.100006
• 7. Ashraf-Kashani, N., & Kumar, R. (2017). High-flow nasal oxygen therapy. BJA Education, 17(2), 63-67. https://doi.org/10.1093/bjaed/mkw041
• 8. Avdeev, S. N., Yaroshetskiy, A. I., Tsareva, N. A., Merzhoeva, Z. M., Trushenko, N. V., Nekludova, G. V., & Chikina, S. Y. (2021). Noninvasive ventilation for acute hypoxemic respiratory failure in patients with COVID-19. The American Journal of Emergency Medicine, 39, 154-157. https://doi.org/10.1016/j.ajem.2020.09.075
• 9. Ferrer, M., Esquinas, A., Leon, M., Gonzalez, G., Alarcon, A., & Torres, A. (2003). Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. American Journal of Respiratory and Critical Care Medicine, 168(12), 1438-1444. https://doi.org/10.1164/rccm.200301-072OC
• 10. Wang, Z., Wang, Y., Yang, Z., Wu, H., Liang, J., Liang, H., ... & Li, S. (2021). The use of non-invasive ventilation in COVID-19: a systematic review. International Journal of Infectious Diseases, 106, 254-261. https://doi.org/10.1016/j.ijid.2021.03.078
• 11. Ferioli, M., Cisternino, C., Leo, V., Pisani, L., Palange, P., & Nava, S. (2020). Protecting healthcare workers from SARS-CoV-2 infection: practical indications. European Respiratory Review, 29(155), 200068. https://doi.org/10.1183/16000617.0068-2020
• 12. Radovanovic, D., Rizzi, M., Pini, S., Saad, M., Chiumello, D. A., & Santus, P. (2020). Helmet CPAP to treat acute hypoxemic respiratory failure in patients with COVID-19: a management strategy proposal. Journal of Clinical Medicine, 9(4), 1191. https://doi.org/10.3390/jcm9041191
• 13. Vitacca, M., Nava, S., Santus, P., & Harari, S. (2020). Early consensus management for non-ICU acute respiratory failure SARS-CoV-2 emergency in Italy: from ward to trenches. European Respiratory Journal, 55(5), 2000632. https://doi.org/10.1183/13993003.00632-2020
• 14. Garcés, H. H., Muncharaz, A. B., & Crespo, R. Z. (2020). Noninvasive mechanical ventilation and COVID-19. Minimizing dispersion. Medicina Intensiva, 44(8), 520. https://doi.org/10.1016/j.medin.2020.03.015
• 15. Brambilla, A. M., Aliberti, S., Prina, E., Nicoli, F., Forno, M. D., Nava, S., ... & Cosentini, R. (2014). Helmet CPAP vs. oxygen therapy in severe hypoxemic respiratory failure due to pneumonia. Intensive Care Medicine, 40(7), 942-949. https://doi.org/10.1007/s00134-014-3325-5
• 16. Cosentini, R., Brambilla, A. M., Aliberti, S., Bignamini, A., Nava, S., Maffei, A., ... & Pelosi, P. (2010). Helmet continuous positive airway pressure vs oxygen therapy to improve oxygenation in community-acquired pneumonia: a randomized, controlled trial. Chest, 138(1), 114-120. https://doi.org/10.1378/chest.09-2290
• 17. Xu, X. P., Zhang, X. C., Hu, S. L., Xu, J. Y., Xie, J. F., Liu, S. Q., ... & Qiu, H. B. (2017). Noninvasive ventilation in acute hypoxemic nonhypercapnic respiratory failure: a systematic review and meta-analysis. Critical Care Medicine, 45(7), e727. https://doi.org/10.1097/CCM.0000000000002361
• 18. Akbudak, İ. H. (2021). Retrospective evaluation of critical patients followed in intensive care with the diagnosis of COVID-19 infection: single center experience. Pamukkale Medical Journal, 14(2), 438-442. https://dx.doi.org/10.31362/patd.848721
• 19. Aliberti, S., Radovanovic, D., Billi, F., Sotgiu, G., Costanzo, M., Pilocane, T., ... & Blasi, F. (2020). Helmet CPAP treatment in patients with COVID-19 pneumonia: a multicentre cohort study. European Respiratory Journal, 56(4), 2001935. https://doi.org/10.1183/13993003.01935-2020
• 20. Bellani, G., Grasselli, G., Cecconi, M., Antolini, L., Borelli, M., De Giacomi, F., ... & Foti, G. (2021). Noninvasive ventilatory support of patients with COVID-19 outside the intensive care units (WARd-COVID). Annals of the American Thoracic Society, 18(6), 1020-1026. https://doi.org/10.1513/AnnalsATS.202008-1080OC
• 21. Chen, R., Liang, W., Jiang, M., Guan, W., Zhan, C., Wang, T., ... & for COVID, M. T. E. G. (2020). Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a nationwide analysis in China. Chest, 158(1), 97-105. https://doi.org/10.1016/j.chest.2020.04.010
• 22. Alhazzani, W., Møller, M. H., Arabi, Y. M., Loeb, M., Gong, M. N., Fan, E., ... & Rhodes, A. (2020). Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19). Intensive Care Medicine, 46(5), 854-887. https://doi.org/10.1007/s00134-020-06022-5
• 23. Kluge, S., Janssens, U., Welte, T., Weber-Carstens, S., Marx, G., & Karagiannidis, C. (2020). German recommendations for critically ill patients with COVID‑19. Medizinische Klinik-Intensivmedizin und Notfallmedizin, 115(3), 111-114. https://doi.org/10.1007/s00063-020-00689-w
• 24. Bakoğlu, E., Kebapçıoğlu, A. S., Ak, A., Girişgin, A. S., & Zararsız, İ. (2013). Investigation of the utility of peripheral venous blood gas ınstead of arterial blood gas in the emergency department. European Journal of Basic Medical Science, 3(2), 29-33.
• 25. Çırak, A. K., Cireli, E., Mertoğlu, A., Deniz, S., Tekgül, S., Varol, Y., ... & Yalnız, E. The feasibility of venous blood gas instead of arterial blood gas in patients hospitalized for chronic obstructive pulmonary diseases acute exacerbation. Journal of İzmir Chest Hospital, 36(1), 28-32. https://doi.org/10.14744/IGH.2022.40469
• 26. Parlak, E. Ş., Pempeci, S., Karalezli, A., & Hasanoglu, H. C. (2019). Can venous blood gases be used instead of arterial blood gases in department of chest diseases? Ankara Medical Journal, 19(1), 157-163. https://doi.org/10.17098/amj.542129
• 27. Menzella, F., Barbieri, C., Fontana, M., Scelfo, C., Castagnetti, C., Ghidoni, G., ... & Facciolongo, N. (2021). Effectiveness of noninvasive ventilation in COVID‐19 related‐acute respiratory distress syndrome. The Clinical Respiratory Journal, 15(7), 779-787. https://doi.org/10.1111/crj.13361
• 28. NHS (NIV). Guidance for the role and use of non-invasive respiratory support in adult patients with COVID-19 (confirmed or suspected), https:// wwwenglandnhsuk/coronavirus/wp-content/uploads/sites/52/2020/03/specialty-guide-NIV-respiratory-support-and-coronavirus-v3pdf [date of access 01 November 2022].
• 29. Mukhtar, A., Lotfy, A., Hasanin, A., El-Hefnawy, I., & El Adawy, A. (2020). Outcome of non-invasive ventilation in COVID-19 critically ill patients: a retrospective observational study. Anaesthesia, Critical Care & Pain Medicine, 39(5), 579. https://doi.org/10.1016/j.accpm.2020.07.012