İntrakranial Menenjiomlar: 41 Vakanın Analizi

Öz

Amaç: Kliniğimizdeki 2013-2018 yılları arasında intrakranial menenjiom tanısı almış 41 hasta retrospektif olarak incelendi. Olguların cinsiyet, tümör yerleşimleri, cerrahi olarak rezeksiyon miktarları ve histopatolojik tanıları değerlendirildi. Yöntem ve Gereç: Olguların tümör yerleşimleri radyolojik görüntüler incelenerek, cerrahi rezeksiyon miktarları Simpson sınıflamasına göre ve histopatolojik tiplerde WHO sınıflamasına göre değerlendirilmiştir. Bulgular: Olguların 31 (%75,6)’i kadın, 10 (%24,4)’u erkekti. Yerleşim yerleri: konveksite 19 (%41,4), sfenoid kanat 7 (%17,1), falks 6 (%14,6) , tentorial 4 (%9,8), serebello-pontin köşe 2 (%4,9) ve olfaktör oluk 2 (%4,9) olarak tespit edildi. Rezeksiyon miktarları Simpson’a göre gradelendi ve 28 (%68,2)’inin grade 1,4 (%9,8)’ünün grade 2,9 (%22)’unun grade 4 olduğu gözlendi. Olguların histopatolojik tanıları ise %43,9’u meningotelyomatöz, %26,8 transisyonel, %14,7 fibroblastik, %7,4 atipik, %2,4 psammomatöz, %2,4 sekretuar, %2,4 miksoid tip olarak saptandı. Sonuç: Menengiomalar benign ekstraaksiyel tümörlerdir. Menengioma tedavisinde karar tümör büyüklüğü ve semptomlara bağlıdır. Semptomatik olduklarında total rezeksiyonla tam kür sağlanabilir. Kavernöz sinüs gibi tehlikeli yerleşimli tümörlerde subtotal rezeksiyon uygulanmakla birlikte, subtotal rezeksiyon ve/veya nükslerde radyoterapinin tedavide yeri bulunmaktadır.

Anahtar Kelimeler

• İntrakranial menengiomlar
• Lokalizasyon
• Histopatoloji

Intracranial Meningiomas: Analysis of 41 Cases

Öz

Objectıve: 41 patients diagnosed with intracranial meningioma in our clinic between 2013 and 2018 were retrospectively analyzed. Gender, tumor location, amount of surgical resection, and histopathological diagnosis of the cases were evaluated. Materıal and Methods: Tumor locations of the cases were evaluated by examining radiological images, surgical resection amounts were evaluated according to Simpson classification and WHO classification for histopathological types. Results: 31 (75.6%) of the cases were female and 10 (24.4%) were male. Locations: convexity 19 (41.4%), sphenoid wing 7 (17.1%), falx 6 (14.6%), tentorial 4 (9.8%), cerebellopontine corner 2 (4.9%), and olfactory groove 2 (4.9%) detected. The amount of resection was graded according to Simpson, and it was observed that 28 (68.2%) were grade 1, 4 (9.8%) were grade 2, and 9 (22%) were grade 4. Histopathological diagnoses of the cases were meningotheliomatous in 43.9%, transitional type in 26.8%, fibroblastic in 14.7%, atypical in 7.4%, psammomatous in 2.4%, secretory type in 2.4%, myxoid type in 2.4%. Conclusıon: Meningiomas are benign extraaxial tumors. The decision to treat meningioma depends on tumor size and symptoms. When they are symptomatic, complete cure can be achieved with total resection. Although subtotal resection is performed in dangerous localized tumors such as cavernous sinus, radiotherapy has a place in the treatment of subtotal resection and/or recurrences. Keywords:

Anahtar Kelimeler

• Intracranial meningiomas
• Localization
• Histopathology

Kaynakça

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