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Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu

Yıl 2018, Cilt: 10 Sayı: 3, 128 - 137, 01.09.2018

Öz

Oral kavite kanserleri baş boyun bölgesi kanserlerinin önemli bir kısmını oluşturmaktadır. Bu bölge kanserlerinin % 90’ından fazlası skuamöz hücreli kanserdir ve %50’nin altında 5 yıllık sağ kalım ve yüksek morbidite oranları ile dünya çapında mercek altında tutulan kanser türlerindendir. Bu yazıda, 20 gün içerisinde radyolojik olarak 2,5 kat büyüklüğe ulaşan, çok agresif seyreden, üst gingival yerleşimli skuamöz hücreli kanser olgusu sunulacaktır. Olguya uygulanan multidisipliner tedavi yaklaşımı ışığında, oral kavite kanserlerindeki prognostik faktörler tartışılacaktır.

Kaynakça

  • 1. Murthy V, Agarwal J, Laskar S, Gupta T, Budrukkar A, Pai P, et al. Analysis of prognostic factors in 1180 patients with oral cavity primary cancer treated with definitive or adjuvant radiotherapy. J Cancer Res Ther. 2010;6(3):282–9.
  • 2. De Paz D, Kao HK, Huang Y, Chang KP. Prognostic Stratification of Patients With Advanced Oral Cavity Squamous Cell Carcinoma. Curr Oncol Rep. 2017;19(10):65
  • 3. Forster G, Cooke TG, Cooke LD, Stanton PD, Bowie G, Stell PM. Tumour growth rates in squamous carcinoma of the head and neck measured by in vivo bromodeoxyuridine incorporation and flow cytometry. Br J Cancer. 1992;65(5):698-702.
  • 4. C. Scullyand J. Bagan, “Oral Squamous Cell Carcinoma Overview,” Oral Oncology. 2009;45(4):301-8.
  • 5. Marur S, Forastiere AA. Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc. 2008;83(4):489–501.
  • 6. Oliver AJ, Helfrick JF, Gard D. Primary oral squamous cell carcinoma: a review of 92 cases. Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons. 1996;54(8):949–954; discussion 55.
  • 7. AJCC Cancer Staging Manual, 8th Edition. American Joint Comitee On Cancer, Executive Office, 633 North Saint Clair Street Chicago IL 60611-3211 (2018).
  • 8. Rahima B, Shingaki S, Nagata M, Saito C. Prognostic significance of perineural invasion in oral and oropharyngeal carcinoma. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2004;97(4):423–31.
  • 9. Fagan JJ, Collins B, Barnes L, D'Amico F, Myers EN, Johnson JT. Perineural invasion in squamous cell carcinoma of the head and neck. Archives of otolaryngology–head & neck surgery. 1998;124(6):637–40.
  • 10. Garzino-Demo P, Dell'Acqua A, Dalmasso P, Fasolis M, La Terra Maggiore GM, Ramieri G, et al. Clinicopathological parameters and outcome of 245 patients operated for oral squamous cell carcinoma. Journal of cranio-maxillo-facial surgery: official publication of the European Association for Cranio-Maxillo-Facial Surgery. 2006;34(6):344–50.
  • 11. Swiecicki PL, Brennan JR, Mierzwa M, Spector ME, Brenner JC. Head and Neck Squamous Cell Carcinoma Detection and Surveillance: Advances of Liquid Biomarkers. Laryngoscope. 2018 Dec 20. doi: 10.1002/lary.27725. [Epub ahead of print] PubMed PMID: 30570748.
  • 12. Nasry WHS, Rodriguez-Lecompte JC, Martin CK. Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma. Cancers (Basel). 2018 Sep22;10(10). pii: E348. doi: 10.3390/cancers10100348. Review. PubMed PMID: 30248985; PubMed Central PMCID: PMC6211032.
  • 13. Pang X, Tang YL, Liang XH. Transforming growth factor-β signaling in head and neck squamous cell carcinoma: Insights into cellular responses. Oncol Lett. 2018 Oct;16(4):4799-4806.
  • 14. Ibrahim MY, Nunez MI, Harun N, Lee JJ, El-Naggar AK, Ferrarotto R, Wistuba I, Myers J, Glisson BS, William WN Jr. PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.Head Neck. 2018 Dec 16. doi: 10.1002/hed.25350. [Epub ahead of print]
  • 15. Zhong L, Liu Y, Wang K, He Z, Gong Z, Zhao Z, Yang Y, Gao X, Li F, Wu H, Zhang S, Chen L. Biomarkers: paving stones on the road towards the personalized precision medicine for oral squamous cell carcinoma. BMC Cancer. 2018 Sep 21;18(1):911. doi: 10.1186/s12885-018-4806-7.

Upper Gingival Squamous Cell Carcinoma Case with Very Aggressive Clinical Course

Yıl 2018, Cilt: 10 Sayı: 3, 128 - 137, 01.09.2018

Öz

Oral cavity cancers constitute an
important part of cancers of the head and neck. More than 90% of these cancers
are squamous cell carcinoma and are among the world's most popular cancer types
with a 5-year survival rate of less than 50% and high morbidity rates. In this
article, a case of squamous cell carcinoma located in the upper gingival
region, radiologically reaching 2.5 times in 20 days, will be presented. In the
light of multidisciplinary treatment approach, prognostic factors in oral
cavity cancers will be discussed.

Kaynakça

  • 1. Murthy V, Agarwal J, Laskar S, Gupta T, Budrukkar A, Pai P, et al. Analysis of prognostic factors in 1180 patients with oral cavity primary cancer treated with definitive or adjuvant radiotherapy. J Cancer Res Ther. 2010;6(3):282–9.
  • 2. De Paz D, Kao HK, Huang Y, Chang KP. Prognostic Stratification of Patients With Advanced Oral Cavity Squamous Cell Carcinoma. Curr Oncol Rep. 2017;19(10):65
  • 3. Forster G, Cooke TG, Cooke LD, Stanton PD, Bowie G, Stell PM. Tumour growth rates in squamous carcinoma of the head and neck measured by in vivo bromodeoxyuridine incorporation and flow cytometry. Br J Cancer. 1992;65(5):698-702.
  • 4. C. Scullyand J. Bagan, “Oral Squamous Cell Carcinoma Overview,” Oral Oncology. 2009;45(4):301-8.
  • 5. Marur S, Forastiere AA. Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc. 2008;83(4):489–501.
  • 6. Oliver AJ, Helfrick JF, Gard D. Primary oral squamous cell carcinoma: a review of 92 cases. Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons. 1996;54(8):949–954; discussion 55.
  • 7. AJCC Cancer Staging Manual, 8th Edition. American Joint Comitee On Cancer, Executive Office, 633 North Saint Clair Street Chicago IL 60611-3211 (2018).
  • 8. Rahima B, Shingaki S, Nagata M, Saito C. Prognostic significance of perineural invasion in oral and oropharyngeal carcinoma. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2004;97(4):423–31.
  • 9. Fagan JJ, Collins B, Barnes L, D'Amico F, Myers EN, Johnson JT. Perineural invasion in squamous cell carcinoma of the head and neck. Archives of otolaryngology–head & neck surgery. 1998;124(6):637–40.
  • 10. Garzino-Demo P, Dell'Acqua A, Dalmasso P, Fasolis M, La Terra Maggiore GM, Ramieri G, et al. Clinicopathological parameters and outcome of 245 patients operated for oral squamous cell carcinoma. Journal of cranio-maxillo-facial surgery: official publication of the European Association for Cranio-Maxillo-Facial Surgery. 2006;34(6):344–50.
  • 11. Swiecicki PL, Brennan JR, Mierzwa M, Spector ME, Brenner JC. Head and Neck Squamous Cell Carcinoma Detection and Surveillance: Advances of Liquid Biomarkers. Laryngoscope. 2018 Dec 20. doi: 10.1002/lary.27725. [Epub ahead of print] PubMed PMID: 30570748.
  • 12. Nasry WHS, Rodriguez-Lecompte JC, Martin CK. Role of COX-2/PGE2 Mediated Inflammation in Oral Squamous Cell Carcinoma. Cancers (Basel). 2018 Sep22;10(10). pii: E348. doi: 10.3390/cancers10100348. Review. PubMed PMID: 30248985; PubMed Central PMCID: PMC6211032.
  • 13. Pang X, Tang YL, Liang XH. Transforming growth factor-β signaling in head and neck squamous cell carcinoma: Insights into cellular responses. Oncol Lett. 2018 Oct;16(4):4799-4806.
  • 14. Ibrahim MY, Nunez MI, Harun N, Lee JJ, El-Naggar AK, Ferrarotto R, Wistuba I, Myers J, Glisson BS, William WN Jr. PI3-kinase pathway biomarkers in oral cancer and tumor immune cells.Head Neck. 2018 Dec 16. doi: 10.1002/hed.25350. [Epub ahead of print]
  • 15. Zhong L, Liu Y, Wang K, He Z, Gong Z, Zhao Z, Yang Y, Gao X, Li F, Wu H, Zhang S, Chen L. Biomarkers: paving stones on the road towards the personalized precision medicine for oral squamous cell carcinoma. BMC Cancer. 2018 Sep 21;18(1):911. doi: 10.1186/s12885-018-4806-7.
Toplam 15 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Klinik Tıp Bilimleri
Bölüm Olgu Sunumu
Yazarlar

İbrahim Aladağ

Mustafa Yazır Bu kişi benim

Murat Songu Bu kişi benim

Hale Arslan Bu kişi benim

Yayımlanma Tarihi 1 Eylül 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 10 Sayı: 3

Kaynak Göster

APA Aladağ, İ., Yazır, M., Songu, M., Arslan, H. (2018). Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi, 10(3), 128-137.
AMA Aladağ İ, Yazır M, Songu M, Arslan H. Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu. Gaziosmanpaşa Tıp Dergisi. Eylül 2018;10(3):128-137.
Chicago Aladağ, İbrahim, Mustafa Yazır, Murat Songu, ve Hale Arslan. “Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu”. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi 10, sy. 3 (Eylül 2018): 128-37.
EndNote Aladağ İ, Yazır M, Songu M, Arslan H (01 Eylül 2018) Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi 10 3 128–137.
IEEE İ. Aladağ, M. Yazır, M. Songu, ve H. Arslan, “Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu”, Gaziosmanpaşa Tıp Dergisi, c. 10, sy. 3, ss. 128–137, 2018.
ISNAD Aladağ, İbrahim vd. “Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu”. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi 10/3 (Eylül 2018), 128-137.
JAMA Aladağ İ, Yazır M, Songu M, Arslan H. Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu. Gaziosmanpaşa Tıp Dergisi. 2018;10:128–137.
MLA Aladağ, İbrahim vd. “Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu”. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi, c. 10, sy. 3, 2018, ss. 128-37.
Vancouver Aladağ İ, Yazır M, Songu M, Arslan H. Çok Agresif Seyirli Üst Gingival Skuamöz Hücreli Karsinom Olgusu. Gaziosmanpaşa Tıp Dergisi. 2018;10(3):128-37.

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