Evaluation of the Relationship Between Postprandial Hypotension and Carotid Intima Thickness in Peritoneal Dialysis Patients/ Periton Diyaliz Hastalarında Postprandiyal Hipotansiyon ve Karotid İntima Kalınlığının Arasındaki İlişkinin Değerlendirilmesi

Öz

Aim: Postprandial hypotension is recognized as a common cause of syncope and falls. This study aimed to determine the frequency of postprandial hypotension in patients undergoing peritoneal dialysis and to investigate the relationship between postprandial hypotension and carotid intima thickness. Materials and Methods: The study was conducted at the Peritoneal Dialysis Unit of Hatay Training and Research Hospital and was designed as a retrospective study. A total of 28 patients on peritoneal dialysis were included. Inclusion criteria were patients older than 18 years of age who had been on peritoneal dialysis for at least three months. Patients wore an ambulatory blood pressure Holter device, and carotid Doppler ultrasonography was performed. Results: The study included 28 patients with a mean age of 48 ± 14.04 years (range: 18–68); 14 were male and 14 were female. The mean systolic blood pressure was 131.2 ± 23.4 mmHg (range: 81–178), and the mean diastolic blood pressure was 75.7 ± 14.2 mmHg (range: 48–99). Ambulatory blood pressure was normal in 12 patients, while 16 patients were hypertensive. Hypertension was present in 25 patients (89.3%). Carotid intima thickness was evaluated in 26 patients, and increased thickness was detected in 10 of them (35.7%). Postprandial hypotension was observed in six patients (21.4%), all of whom had a history of hypertension. Conclusion: In this study, the prevalence of hypertension was 89.3%, and the frequency of postprandial hypotension was 21.4%. Increased carotid intima thickness was identified in 35.7% of the patients. No significant correlation was observed between postprandial hypotension and carotid intima thickness.

Anahtar Kelimeler

• Carotid Intima Thickness
• Hypertension
• Peritoneal Dialysis
• Postprandial Hypotension

Etik Beyan

The approval of the ethics committee for this study was obtained from the Ethics Committee of Mustafa Kemal University (Date and no: 12.10.2023; 19).

Periton Diyaliz Hastalarında Postprandiyal Hipotansiyon ve Karotid İntima Kalınlığının Arasındaki İlişkinin Değerlendirilmesi

Öz

Amaç: Postprandiyal hipotansiyon, senkop ve düşmelerin yaygın bir nedeni olarak kabul edilmektedir. Bu çalışmada, periton diyalizi hastalarında postprandiyal hipotansiyon sıklığını belirlemeyi ve karotid intima kalınlığı ile olan ilişkisini araştırmayı amaçladık. Gereç ve Yöntem: Çalışma, Hatay Eğitim ve Araştırma Hastanesi Periton Diyalizi Merkezi'nde yürütülmüş olup, retrospektif tasarıma sahip bir araştırmadır. Çalışmaya toplam 28 periton diyalizi hastası dahil edildi. Çalışmaya 18 yaşından büyük ve en az üç aydır periton diyalizi yapılan hastalar dahil edildi. Hastalara ambulatuvar kan basıncı holter cihazı takıldı ve karotid doppler yapıldı. Bulgular: Çalışmaya toplam 28 hasta dahil edildi. Hastaların yaş ortalaması 48 ±14,04 (18-68 arası) idi. Hastaların 14'ü erkek, 14'ü kadındı. Ortalama sistolik kan basıncı 131.2±23,4 mmHg (81-178 arası), ortalama diyastolik kan basıncı ise 75,7±14,2 mmHg (48-99 arası) idi. 12 hastada ambulatuvar kan basıncı normal, 16 hastada ise hipertansiyon saptandı. Hastaların 25'inde (%89,3) hipertansiyon mevcuttu. Toplam 26 hastada karotid intima kalınlığı incelendi ve hastaların %35,7’sinde (10 hasta) kalınlık tespit edildi. Postprandiyal hipotansiyon altı hastada (%21,4) saptandı. Postprandiyal hipotansiyon olan tüm hastaların hipertansiyon öyküsü vardı. Sonuç: Çalışmamızda hipertansiyon prevalansı %89,3 olarak bulundu. Postprandiyal hipotansiyon sıklığı %21,4 idi. Hastaların %35,7'sinde (26 hastadan) karotid intima kalınlığı artışı saptandı. Postprandiyal hipotansiyon ile karotid intima kalınlığı arasında bir ilişki tespit edilmedi.

Anahtar Kelimeler

• Karotid İntima Kalınlaşması
• Hipertansiyon
• Periton Diyalizi
• Postprandiyal Hipotansiyon

Kaynakça

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